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Amonafide Targeting NTSR1-PI3K/AKT/mTOR Signaling Attenuates Vascular Remodeling in Pulmonary Arterial Hypertension

Yong‐Jian Zhu, Jie‐Jian Kou, Ya‐Cong Bo, Meng‐Jie Zhang, Xin Fan, Lu‐Ling Zhao, Yi Yan, Hong Da Zhang, Wen‐Hui Wu, Ping Yuan, Yan Liu, Jun‐Zhuo Shi, Xiao‐Bin Pang, Yang‐Yang HeFirst Affiliated Hospital of Zhengzhou University. Huaihe Hospital and Henan University. Zhengzhou University. Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Fuwai Hospital and Peking Union Medical College. Shanghai Pulmonary Hospital and School of Medicine Tongji University. China Journal of the American Heart AssociationJ Am Heart Assoc […]

Amonafide Targeting NTSR1-PI3K/AKT/mTOR Signaling Attenuates Vascular Remodeling in Pulmonary Arterial Hypertension Read More »

Diagnosis of a Right Congenital Diaphragmatic Hernia in a Neonate with POCUS

Alyssa DaVolio, Brandon S. Hays, Matthew O. Thompson, Michael J. Walsh, Parvesh M. Garg, Ricardo J. RodriguezAtrium Health Wake Forest Baptist, Brenner Children’s Hospital and Wake Forest University School of Medicine.United States Point of Care Ultrasound JournalPOCUS J 2026; 11: 121-125DOI: 10.24908/pocusj.v11i01.19486 AbstractPoint of care ultrasound (POCUS) can be used to diagnose neonatal lung diseases, especially

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Descriptive study of the effects of treprostinil and/or epoprostenol in newborn infants with inhaled NO refractory persistent pulmonary hypertension of the newborn (PPHN)

Charlotte Mazepa, Sébastien Mur, Géraldine Gascoind, Laurent Storme, Nicolas Joram, Caroline Viard, Yves Dulac, Marine Butini, Sophie BreinigChildren’s Hospital, CHU de Toulouse and Université de Toulouse. Lille University Hospital. Jeanne-de-Flandre Hospital and CHU de Lille. Nantes University Hospital. Hôpital Femme-Mère-Enfant, Hospices civils de Lyon and Université Claude-Bernard-Lyon. France TherapeuticsTherapie 2026; DOI: 10.1016/j.therap.2026.03.001 AbstractBackground: Epoprostenol and treprostinil, prostacyclin

Descriptive study of the effects of treprostinil and/or epoprostenol in newborn infants with inhaled NO refractory persistent pulmonary hypertension of the newborn (PPHN) Read More »

Fetal Intervention Using an Everolimus-Eluting Stent in HLHS With Intact Atrial Septum

Iris Scharnreitner, Julian Hochpöchler, Felix Mögel, Florian Putre, Judith Rittenschober-Böhm, Georg Grüßenberger, Simona Anna Marcora, Peter Oppelt, Gerald Tulzer, Andreas TulzerKepler University Hospital and Johannes Kepler University Linz. ASST Grande Ospedale Metropolitano Niguarda.Austria and Italy Journal of the American College of Cardiology Case ReportsJACC Case Rep 2026;DOI: 10.1016/j.jaccas.2026.108155 AbstractBackground: In utero stenting of the atrial septum has

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Does preservation of antegrade pulmonary blood flow reduce pulmonary arteriovenous malformations after bidirectional Glenn? A retrospective observational study

Sachin Talwar, Tanvi Sunil Kumar, Vishal Vinayak Bhende, Mathangi KrishnakumarAll India Institute of Medical Sciences. Sri Sathya Sai Sanjeevani Centre for Child Heart Care and Training in Pediatric Cardiac Skills. St. John’s Medical College Hospital.India Cardiology in the YoungCardiol Young 2026; DOI: 10.1017/S1047951126112232 AbstractBackground: Pulmonary arteriovenous malformations (PAVMs) are a recognised cause of progressive cyanosis following bidirectional

Does preservation of antegrade pulmonary blood flow reduce pulmonary arteriovenous malformations after bidirectional Glenn? A retrospective observational study Read More »

Prevalence and Risk Factors for Pulmonary Hypertension in Children with Sickle Cell Disease: A Prospective Observational Study from Central India

Kapil Dev Rabha, Rajkumar Kundavaram, Pooja Soni, Amber Kumar, NarendraKumar Chaudhary, Bhavna DhingraLower Assam Hospital and Research Centre. All India Institute of Medical Sciences.India Indian Journal of PediatricsInd J Pediatr 2026; DOI: 10.1007/s12098-026-06175-z AbstractAbstract Not Available CategoryClass V. Pulmonary Hypertension Associated with Hematological, Systemic, Metabolic, Nutritional and Other Disorders Age Focus: Pediatric Pulmonary Vascular Disease Fresh

Prevalence and Risk Factors for Pulmonary Hypertension in Children with Sickle Cell Disease: A Prospective Observational Study from Central India Read More »

Hemodynamic effects of high frequency oscillatory ventilation versus conventional mechanical ventilation in term neonates with persistent pulmonary hypertension: a single-center randomized trial

Doaa El Amrousy, Hassan Koura, Noura Abdou, Mostafa Awny, Abdelrahman ElmashadTanta University.Egypt Italian Journal of MedicineItal J Med 2026; 52: DOI: 10.1186/s13052-026-02272-z AbstractBackground: We aimed to evaluate the hemodynamics in full-term neonates with persistent pulmonary hypertension (PPH) on high frequency oscillatory ventilation (HFOV) versus conventional mechanical ventilation (CMV).Methods: This trial was conducted on 64 full-term neonates with PPH

Hemodynamic effects of high frequency oscillatory ventilation versus conventional mechanical ventilation in term neonates with persistent pulmonary hypertension: a single-center randomized trial Read More »

Pulmonary arterial hypertension in infancy: A case series

N. V. Shashikala, K. M. Arun, R. C. Ashwini, Muganagowda PatilBapuji Child Health Institute and Research Centre. India Tropical DoctorTrop Doct 2026;DOI: 10.1177/00494755261451113 AbstractThiamine deficiency is a reversible cause of severe pulmonary arterial hypertension (PAH) in early infancy, particularly among exclusively breastfed infants of mothers consuming polished rice-based diets. This retrospective case series (July 2023-July 2025)

Pulmonary arterial hypertension in infancy: A case series Read More »

The preponderance of genetic variations in paediatric pulmonary hypertension

Julien Grynblat, Melanie Eyries, Marine Ambar-Akkaoui, Marilyne Levy, Mathilde Meot, Isabelle Szezepanski, Julien Ranchoup, Alessia Callegari, Julie Karila-Cohen, Caroline Bonnet, Pierre Marijon, Jerome Champ, Florence Coulet, Caroline Ovaert, Frederic Perros, Fabrice Antigny, Pascale Maragnes, Guy Vaksmann, Marc Humbert, Sophie Guiti Malekzadeh Milani, David Montani Damien BonnetHôpital Necker-Enfants malades, AP-HP, Université de Paris Cité, Université Paris-Saclay,

The preponderance of genetic variations in paediatric pulmonary hypertension Read More »

Gap between guidelines and practice: echocardiography reporting in neonatal pulmonary hypertension

Sophia Gremont, Eveliina Ronkainen, Merja KallioUniversity of Oulu. Oulu University Hospital. Helsinki University Hospital, University of Helsinki.Finland Cardiology in the YoungCardiol Young 2026; DOI: 10.1017/S104795112611292X AbstractObjectives: Targeted neonatal echocardiography is increasingly integrated into neonatal care and plays a crucial role in the evaluation and management of persistent pulmonary hypertension of the newborn. The objective of this study

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