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Challenges in clinical identification of right ventricular dysfunction in preterm infants with persistent pulmonary hypertension of the newborn

Faith Zhua, Caio Barbosa de Oliveira, Nada Mohsen, Ashraf Kharrat, Poorva Deshpande, Luc Mertens, Amish JainMount Sinai Hospital, Hospital for Sick Children and University of Toronto.Canada Early Human DevelopmentEarly Hum Dev 2024; 190DOI: 10.1016/j.earlhumdev.2024.105942 AbstractBackground: Right ventricular dysfunction, typically qualitatively diagnosed (Q-RVd) in preterm infants, requires echocardiography which is not always acutely available. We aimed to identify […]

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Survival of Infants With Severe Congenital Kidney Disease After ECMO and Kidney Support Therapy

Kara Short, Martha McBride, ScottAnderson, Rachel Miller, Daryl Ingram, Carl Coghill, Brian Sims, David AskenaziChildren’s of Alabama and University of Alabama at Birmingham.United States PediatricsPediatrics 2024; DOI: 10.1542/peds.2023-062717 AbstractCongenital kidney failure not only affects the homeostatic functions of the kidney, but also affects neonatal respiratory integrity. Until recently, extracorporeal membrane oxygenation (ECMO) support was not used

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Survival outcomes for congenital heart disease from Southern Malaysia: results from a congenital heart disease registry

Mohd Nizam Mat Bah, Aina Salwa Kasim, Mohd Hanafi Sapian, Emieliyuza Yusnita AliasHospital Sultanah Aminah.Malaysia Archives of Diseases in ChildhoodArch Dis Child 2024;DOI: 10.1136/archdischild-2023-326622 AbstractObjective: Limited population-based studies are available on the survival of congenital heart disease (CHD) from lower- and middle-income countries. Therefore, we evaluated the survival from birth until 15 years and associated factors for

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Mitochondrial network dynamics in pulmonary disease: Bridging the gap between inflammation, oxidative stress, and bioenergetics

Marissa D. Pokharel, Alejandro Garcia-Flores, David Marciano, Maria C. Franco, Jeffrey R. Fineman, Saurabh Aggarwal, Ting Wang, Stephen M. BlackFlorida International University. University of California, San Francisco.United States Redox BiologyRedox Biol 2024; 70:DOI: 10.1016/j.redox.2024.103049 AbstractOnce thought of in terms of bioenergetics, mitochondria are now widely accepted as both the orchestrator of cellular health and the gatekeeper

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Rescuing lung development through embryonic inhibition of histone acetylation

Giangela Stokes, Zhuowei Li, Nicole Talaba, William Genthe, Maria B. Brix, Betty Pham, Mark D. Weihold, Gracia Sandok, Rebecca Hernan, Julia Wynn, Haiyang Tang, Diana M. Tabima, Allison Rodgers, Timothy A. Hacker, Naomi C. Chesler, Pan Zhang, Rabi Murad, Jason X.-J. Yuan, Yufeng Shen, Wendy K. Chung, David J. McCulleyUniversity of California, San Diego. University

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Implantation of atrial flow regulator devices in patients with congenital heart disease and children with severe pulmonary hypertension or cardiomyopathy-an international multicenter case series

Gianfranco Butera, Enrico Piccinelli, Adam Kolesnik, Kostantin Averin, Cameron Seaman, Biagio Castaldi, Elena Cuppini, Alain Fraisse, Carles Bautista-Rodriguez, Sebastien Hascoet, Carmen D’Amore, Alban-Elouen Baruteau, Pedro Betrián Blasco,Lisa Bianco, Andreas Eicken, Matthew Jones, James A. Kuo, Grazyna Brzezinska RajszysBambino Gesù Hospital and Research Institute. Politecnico di Torino. Children’s Memorial Health Institute. Stollery Children’s Hospital. Padova University.

Implantation of atrial flow regulator devices in patients with congenital heart disease and children with severe pulmonary hypertension or cardiomyopathy-an international multicenter case series Read More »

Short term effect of intravenous treprostinil in term and preterm infants with pulmonary hypertension

Yoo-Jin Kim, Seung Han Shin, Ee-Kyung Kim, Han-Suk KimChung-buk National University Hospital. Seoul National University College of Medicine. Seoul National University Children’s Hospital. Republic of Korea BioMed Central PediatricsBMC Pediatr 2024; 23:DOI: 10.1186/s12887-023-04501-4 AbstractBackground: Pulmonary hypertension (PH) is a life-threatening condition in newborns. We aimed to assess the clinical and echocardiographic responses of term and preterm infants

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Effect of face mask on pulmonary artery pressure during echocardiography in children and adolescents

Alireza Ahmadi, Mohammad Reza Sabri, Zohreh Sadat NavabiIsfahan University of Medical Sciences.Iran Clinical and Experimental PediatricsClin Exp Pediatr 2024;DOI: 10.3345/cep.2023.01172 AbstractBackground: Face masks have become an important tool for preventing the spread of respiratory diseases. However, we hypothesized that face masks with reduced nasal airflow may alter pulmonary artery systolic pressure (PASP).Purpose: This study aimed to evaluate the

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Pulsed Doppler assessment of pulmonary vein obstruction.

Jeffrey F. Smallhorn, Helder Pauperio, Lee Benson, Robert M. Freedom, Richard D. RoweHospital for Sick Children and University of Toronto.Canada American Heart JournalAm Heart J 1985; 110: 483-486DOI: 10.1016/0002-8703(85)90174-7 AbstractStenosis of the individual pulmonary veins is a rare condition, often presenting as recurrent pneumonia. Apart from radiologic features suggestive of pulmonary venous congestion, cardiac catheterization and angiocardiography have

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Variants in the SARS2 gene cause HUPRA syndrome with atypical features: two case reports and review of the literature

Elias Edward Lahham, JuhinaJamal Hasassneh, Dua Osamah Adawi, Mohamad Khaled IsmailAugusta Victoria Hospital. Beit-Jala Governmental Hospital.Palestine Oxford Medical Case ReportsOxford Med Case Rep 2023; 11: 407–409DOI: 10.1093/omcr/omad119 AbstractHyperuricemia, pulmonary hypertension, renal failure in infancy, and alkalosis (HUPRA syndrome) is a rare autosomal recessive mitochondrial disease with a prevalence of <1:1 000 000, due to variations in

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