Medical Therapy. Efficacy or Lack of Efficacy

Drugs in Focus: Octreotide Use in Children With Gastrointestinal Disorders

Emmanuel Mas, Osvaldo Borrelli, Ilse Broekaert, J. Martin de-Carpi, Jernej Dolinsek, Erasmo Miele, Corina Pienar, C. Ribes Koninckx, Ruth-Anne Thomassen, Mike Thomson, Christo Tzivinikos, Marc A. BenningaHôpital des Enfants and Université de Toulouse. Great Ormond Street Hospital. University Hospital Cologne and University of Cologne. Hospital Sant Joan de Déu. University Medical Centre Maribor. University of […]

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Medical Interventions for Chylothorax and their Impacts on Need for Surgical Intervention and Admission Characteristics: A Multicenter, Retrospective Insight

Rohit S. Loomba, Joshua Wong, Megan Davis, Sarah Kane, Brian Heenan, Juan S. Farias, Enrique G. Villarreal, Saul FloresChicago Medical School and Advocate Children’s Hospital. Escuela de Medicina y Ciencias de la Salud. Texas Children’s Hospital.United States and Mexico Pediatric CardiologyPediatr Cardiol 2021; 42: 543-553DOI: 10.1007/s00246-020-02512-x AbstractThe incidence of chylothorax is reported from 1-9% in pediatric

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Adjunct Targeted Biologic Inhibition Agents to Treat Aggressive Multivessel Intraluminal Pediatric Pulmonary Vein Stenosis

Ryan Callahan, Mark W. Kieran, Christopher W. Baird, Steven D. Colan, Kimberlee Gauvreau, Chistina M. Ireland, Audrey Marshall, Laureen M. Sena, Sara O. Vargas, Kathy J. JenkinsBoston Children’s Hospital and Harvard Medical School. Floating Hospital for Children at Tufts Medical Center. UMass Memorial Medical Center.United States Journal of PediatricsJ Pediatr 2018; 198: 29-35DOI: 10.1016/j.jpeds.2018.01.029 AbstractObjective: To evaluate

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Intervening with the Nitric Oxide Pathway to Alleviate Pulmonary Hypertension in Pulmonary Vein Stenosis

Richard W. B. van Duin, Kelly Stam, André Uitterdijk, Beatrijs Bartelds, A. H. Jan Danser, Irwin K. M. Reiss, Dirk J. Duncker, Daphne MerkusErasmus MC Rotterdam. Sophia Children’s Hospital. University Hospital, LMU Munich.Netherlands and Germany Journal of Clinical MedicineJ Clin Med 2019; 8: DOI: 10.3390/jcm8081204 AbstractPulmonary hypertension (PH) as a result of pulmonary vein stenosis (PVS)

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Systemic Sirolimus to Prevent In-Stent Stenosis in Pediatric Pulmonary Vein Stenosis

Ryan Callahan, Jesse J. Esch, Grace Wang, Christina M. Ireland, Kimberlee Gauvreau, Kathy J. JenkinsBoston Children’s Hospital and Harvard Medical School.United States Pediatric CardiologyPediatr Cardiol 2020; 41: 282-289DOI: 10.1007/s00246-019-02253-6 AbstractEvaluate the efficacy of systemic sirolimus (rapamycin) in preventing in-stent stenosis (ISS) in pediatric intraluminal pulmonary vein stenosis (PVS). Report the adverse events related to sirolimus therapy.

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Pulmonary Vein Stenosis in Children: A Programmatic Approach Employing Primary and Anatomic Therapy

James A. Kuo, Christopher J. PetitChildren’s Healthcare of Atlanta and Emory University. Columbia University Vagelos College of Physicians and Surgeons and Morgan Stanley Children’s Hospital of New York.United States ChildrenChildren 2021; 8: DOI: 10.3390/children8080663 AbstractPulmonary vein stenosis (PVS) is a difficult condition to treat due to recurrence and progression. In 2017, we developed a comprehensive PVS

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Outcomes in Establishing Individual Vessel Patency for Pediatric Pulmonary Vein Stenosis

Ryan Callahan, Kimberlee Gauvreau, Audrey C. Marshall, Laureen M. Sena, Christopher W. Baird, Christina M. Ireland, Kerry McEnaney, Elsa C. Bjornlund, Juliana T. Mendonca, Kathy J. JenkinsBoston Children’s Hospital and Harvard Medical School.United States ChildrenChildren 2021; 8: DOI: 10.3390/children8030210 AbstractThe purpose of this study was to determine what patient and pulmonary vein characteristics at the diagnosis

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A Canadian, retrospective, multicenter experience with selexipag for a heterogeneous group of pediatric pulmonary hypertension patients

David Youssef, Susan Richards, Sabine Lague, Catherine Sheppard, Jenna Smith, Erika Vorhies, Martin Hosking, Matthew Pietrosanu, Angela BatesStollery Children’s Hospital. Alberta Children’s Hospital. British Columbia Children’s Hospital. University of Alberta.Canada Frontiers in PediatricsFront Pediatr 2023; 11: DOI: 10.3389/fped.2023.1055158 AbstractIntroduction: Selexipag, an oral nonprostanoid prostaglandin receptor agonist, has led to reduced morbidity and mortality in adults with pulmonary

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Successful Eisenmenger syndrome-targeted drug therapy in pregnant women: a case series and literature review

W. Chen, J. Chen, M. Peng, J. Luo, Y. Chen, H. Qiu, J. LiThe Second Xiangya Hospital of Central South University. China British Journal of Obstetrics and GynaecologyBJOG 2023; 130: 923-931DOI: 10.1111/1471-0528.17427 AbstractObjective: To clarify the real-world outcomes in pregnant women with Eisenmenger syndrome (ES) in the new therapeutic era and provide a literature review.Design: Retrospective case and

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Demonstration of Safety in Wild Type Mice of npFOXF1, a Novel Nanoparticle-Based Gene Therapy for Alveolar Capillary Dysplasia with Misaligned Pulmonary Veins

Fatemeh Kohram, Zicheng Deng, Yufang Zhang, Abid Al Reza, Enhong Li, Olena A Kolesnichenko, Samriddhi Shukla, Vladimir Ustiyan, Jose Gomez-Arroyo, Anusha Acharya, Donglu Shi, Vladimir V. Kalinichenko, Alan P. KennyUniversity of Cincinnati and Cincinnati Children’s Hospital Medical Center and University of Cincinnati.United States BiologicsBiologics 2023; 17: 43-55DOI: 10.2147/BTT.S400006 AbstractIntroduction: Alveolar Capillary Dysplasia with Misaligned Pulmonary Veins (ACDMPV)

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