Medical Therapy. Efficacy or Lack of Efficacy

Fetal therapies in congenital diaphragmatic hernia: a review of possibilities and practical challenges

Adriana Dekirmendjian, Fabian Doktor, Lina Antounians, Augusto ZaniUniversity of Toronto and Hospital for Sick Children. St. Louis Children’s Hospital and Washington University. Canada and United States Seminars in Fetal and Neonatal MedicineSemin Fetal Neonatal Med 2025; DOI: 10.1016/j.siny.2025.101656 AbstractCongenital diaphragmatic hernia (CDH) is characterized by pulmonary hypoplasia. CDH lungs exhibit an inflammatory signature with impaired growth, […]

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Less is More: ECMO Utilization and Outcomes in Congenital Diaphragmatic Hernia

Anastasia M. Kahan, Sommer Glasgow, Bradley A. Yoder, Michelle Yang, Christian C. Yost, Kelsea Peterson, Jack H. Scaife, Christopher E. Clinker, Erica Arnold, Stephen J. Fenton, Zachary J. Kastenberg, Robert A. Swendiman, Scott S. Short, Katie W. RussellUniversity of Utah.United States Journal of Pediatric SurgeryJ Pediatr Surg 2025; DOI: 10.1016/j.jpedsurg.2025.162571 AbstractPurpose: Infants with congenital diaphragmatic hernia (CDH)

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Utility of inhaled nitric oxide for pulmonary hypertension in cyanotic congenital heart disease: a cohort study with propensity score matching

Xiaofeng Wang, Chenyu Li, Shilin Wang, Zhiyuan Zhu, Qinnan Chen, Ruihuan Shen, Xu WangNational Center for Cardiovascular Disease and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College. Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences amd Affiliated Cardiovascular Hospital of Kunming Medical University. Sir Run Run Shaw Hospital and Zhejiang University

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SUL-150 Limits Vascular Remodeling and Ventricular Failure in Pulmonary Arterial Hypertension

Lysanne M. Jorna, Dalibor Nakládal, Johannes N. van Heuveln, Diederik E. van der Feen, Quint A. J. Hagdorn, Guido P. L. Bossers, Annemieke van Oosten, Michel Weij, Ludmila Tkáciková, Sona Tkáciková, Robert H. Henning, Martin C. Harmsen, Rolf M. F. Berger, Guido KrenningUniversity Medical Center Groningen, University of Groningen. Comenius University Bratislava. University of Heidelberg.

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IDO-1 Promotes Pulmonary Vascular Remodeling Via Kynurenine Pathway in Pulmonary Arterial Hypertension

Zongye Cai, Ly Tu, Siyu Tian, Lin Deng, Yahong Fu, Carole Phan, Thierry P. P. van den Bosch, Karin Tran‐Lundmark, Bence M. Nagy, Horst Olschewski, Xiaoxuan Li, Sihao Wang, Danan Wang, Yi Yan, Lijun Fu, Karin A. Boomars, Christophe Guignabert, Daphne MerkusSecond Affiliated Hospital and Zhejiang University School of Medicine. Erasmus MC and University Medical Center. Pathophysiologie et Innovation Thérapeutique (HPPIT) and Université Paris-Saclay, School of Medicine. Eighth Affiliated Hospital of Sun Yat-sen University. Lund University and Skane University Hospital. Medical University

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Targeted Therapy for Complex Lymphatic Anomalies in Patients with Noonan Syndrome and Related Disorders

Erika K. S. M. Leenders, Vera C. van den Brink, Lotte E. R. Kleimeier, Danielle T. J. Woutersen, Catelijne H. Coppens, Jeroen den Hertog, Willemijn M. Klein, Tuula Rinne, Sabine L. Vrancken, Saskia N. de Wildt, Jos M. T. Draaisma, Joris FuijkschotRadboud University Medical Center and Amalia Children’s Hospital. University Medical Center Utrecht. Leiden University.

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Pharmacological Treatment Practices for Patients with Congenital Heart Disease and Pulmonary Hypertension in Japan: Insights from the Japanese Association of Congenital Heart Disease Registry (JACPHR)

Taku Ishii, Keiko Uchida, Susumu Hosokawa, Reina Ishizaki, Naofumi F. Sumitomo, Yoshiyuki Furutani, Hidekazu Ishida, Shinichi Takatsuki, Kei Inai, Kunihiko Takahashi, Shigetoyo Kogaki, Hiroyuki Fukushima, Yuichi Tamura, Hiroyuki Yamagishi, Shozaburo Doi, Japanese Association of Congenital Heart Disease Registry (JACHDR) membersInstitute of Science Tokyo. Keio University School of Medicine, Tokyo Medical University. Japanese Red Cross Mushashino

Pharmacological Treatment Practices for Patients with Congenital Heart Disease and Pulmonary Hypertension in Japan: Insights from the Japanese Association of Congenital Heart Disease Registry (JACPHR) Read More »

Severe pertussis complicated by pulmonary hypertension in a Moroccan infant: a case report

Mehdi Belhakim, Zineb El jaouhahri, Aicha Boudar, Loubna Benaddi, Karima Naanani, Rachida Habbal, Abdelaziz ChlilekUniversity Hospital Ibn Rochd, Children’s Hospital and University Hassan II.Morocco Journal of Medical Case ReportsJ Med Case Rep 2025; 19: DOI: 10.1186/s13256-024-04898-1 AbstractBackground: Despite high vaccination coverage among children, pertussis continues to pose a significant public health challenge in Morocco. Mortality primarily affects

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Pharmacologic Management of Segmental Pulmonary Hypertension in Children After Unifocalization and Pulmonary Artery Reconstruction: Initial Experience

Julian E. Cameron, Doff B. McElhinney, Esther Liu, Rachel K. Hopper, Ritu Asija, Manchula Navaratnam, Frank L. Hanley, Jeffrey A. FeinsteinLucile Salter Packard Children’s Hospital and Stanford University School of Medicine. Children’s Hospital Los Angeles and Keck School of Medicine University of Southern California.United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70134 AbstractSegmental pulmonary hypertension (PH)

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Successful interventional closure of patent ductus arteriosus in three pediatric cases with congenital heart disease and severe pulmonary hypertension: a case series and literature review

Xiong-Yu Liao, Jun-Jie Li, Shao-Ying Zeng, Zhi-Wei Zhang, Yu-Mei XieChildren’s Medical Center, Sun Yat-sen Memorial Hospital and Sun Yat-sen University. Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences) and Southern Medical University.China Fontiers in Cardiovascular MedicineFront Cardiovasc Med 2025; DOI: 10.3389/fcvm.2025.1628666 AbstractPurpose: To report three cases of successful closure of patent ductus arteriosus (PDA) with severe

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