Medical Therapy. Efficacy or Lack of Efficacy

Early Oxygenation and Mortality in Infants Treated with Inhaled Nitric Oxide (iNO) for Persistent Pulmonary Hypertension of the Newborn (PPHN)

Marina S. Oren, Kikelomo Babata, June Hu, Venkatakrishna Kakkilaya, Patti J. Burchfield, Michelle Hagans, L. Steven Brown, Satyan Lakshminrusimha, Vishal KapadiaUniversity of Texas Southwestern Medical Center. Texas Health Presbyterian Hospital of Dallas. Parkland Health & Hospital System. University of California Davis Children’s Hospital.United States Journal of Pediatrics: Clinical PracticeJ Pediatr Clin Pract 2025; 18: DOI: 10.1016/j.jpedcp.2025.200189 […]

Early Oxygenation and Mortality in Infants Treated with Inhaled Nitric Oxide (iNO) for Persistent Pulmonary Hypertension of the Newborn (PPHN) Read More »

Use of milrinone in pediatric intensive care units: a multicenter survey of French-speaking countries

Florian Manoeuvrier, Morgan Recher, Marion Grimaud, Sylvain Renolleau, Olivier Brissaud, Stéphane Leteurtre, Mehdi Oualha, Charles de Marcellus, Groupe Francophone de Réanimation et d’Urgence PédiatriquesCentre-Université de Paris and Necker-Enfants Malades. CHU Amiens-Picardie. Univ.ersity of Lille and CHU Lille. CHU Bordeaux and Pellegrin-Enfants Hospital. France European Journal of PediatricsEur J Pediatr 2025; 184: DOI: 10.1007/s00431-025-06589-5 AbstractPurpose: To assess the

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Marked improvement in severe pulmonary arterial hypertension following airway infection in a patient with a heterozygous BMP9 nonsense mutation: a case report

Makito Sakurai, Yohei Yamaguchi, Kei Takasawa, Susumu Hosokawa, Taku IshiiInstitute of Science Tokyo. Japanese Red Cross Musashino Hospital.Japan European Heart Journal Case ReportsEur Heart J Case Rep 2025; 9: DOI: 10.1093/ehjcr/ytaf386 AbstractBackground: Pulmonary arterial hypertension (PAH) is a severe and life-threatening disease. Genetic factors, inflammation and immune system play important roles in their pathogenesis. However, their precise

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Phenoxybenzamine: Old Wine in a Bright New Bottle-Taming the wild side of Phenoxybenzamine

R. Benedict Raj, Srinath Reddy Narahari, Vasudev Vemala, Jyotiprakash ReddyAster Ramesh Hospitals.India Journal of Pharmacy and BioAllied SciencesJ Pharm Bioall Sci 2025; 17 (Suppl 3): S2135-S2137DOI: 10.4103/jpbs.jpbs_868_25 AbstractBackground: Phenoxybenzamine (PBZ), a long-acting α-blocker, was once widely used in pediatric cardiac surgeries but fell out of favor due to concerns about systemic hypotension. In the context of developing

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Two case reports of idiopathic prenatal closure of the ductus arteriosus complicated at birth by severe pulmonary hypertension successfully treated without intubation

Leonce Mwizerwa, Raphael Joye, Vladimir L. Cousin, Iliona Malaspinas, Maya Bouhabib, Hugues Lucron, Maurice Beghetti, Julie WackerGeneva University Hospitals and University of Geneva. AP-HP Paris-Saclay University and Bicêtre Hospital.Switzerland and France Translational PediatricsTrans Pediatr 2025; 14: 2374-2380DOI: 10.21037/tp-2025-264 AbstractBackground: Prenatal closure of the ductus arteriosus (DA) is an uncommon but potentially severe condition that can result in

Two case reports of idiopathic prenatal closure of the ductus arteriosus complicated at birth by severe pulmonary hypertension successfully treated without intubation Read More »

Pulmonary Hemodynamics and Long-Term Outcomes in Children with Pulmonary Hypertension-Associated Bronchopulmonary Dysplasia

Eric D. Austin, Mary P. Mullen, Catherine M. Avitabile, Usha S. Krishnan, Erika B. Rosenzweig, Roberta L. Keller, John P. Kinsella, Delphine Yung, Lea Steffes, Angela Bates, Eleni G. Elia, Lewis H. Romer, Sharon McGrath-Morrow, Meghan L. Bernier, Kenneth D. Mandl, J.Usha Raj, Lynn A. Sleeper, Steven H. AbmanVanderbilt University Medical Center. Boston Children’s Hospital

Pulmonary Hemodynamics and Long-Term Outcomes in Children with Pulmonary Hypertension-Associated Bronchopulmonary Dysplasia Read More »

Part 8: Pediatric Advanced Life Support: 2025 American Heart Association and American Academy of Pediatrics Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care

Javier J. Lasa, Gurpreet S. Dhillon, Jonathan P. Duff, Jennifer Hayes, Beena D. Kamath-Rayne, Arielle Levy, Melissa Mahgoub, Ryan W. Morgan, Taylor McCormick, Joan S. Roberts, Catherine E. Ross, Stephen M. Schexnayder, Todd Sweberg, Santiago O. Valdés, Alexis A. TopjianChildren’s Health Systems of Texas and UT Southwestern Medical Center. Children’s Hospital of Philadelphia, University of Pennsylvania School of Medicine. Lucile Packard Children’s Hospital and Stanford Medical Center. University of Alberta and Stollery Children’s Hospital. Children’s Hospital Orange County. American Academy of Pediatrics.

Part 8: Pediatric Advanced Life Support: 2025 American Heart Association and American Academy of Pediatrics Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Read More »

Persistent Low-Output Neonatal Chylothorax: How Long Are We Justified to Wait for Pleurodesis in Partial Responders?

G. Rollo, A. Zarfati, G. Burini, L. Valfre, C. Iacusso, I. Capolupo, B. D. Iacobelli, P. Bagolan, A. Conforti, F. FusaroBambino Gesù Children’s Hospital IRCCS. Italy Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71311 AbstractAims: The aim of our study was to review our experience regarding the management of neonatal chylothorax, with particular focus on outcomes of partial

Persistent Low-Output Neonatal Chylothorax: How Long Are We Justified to Wait for Pleurodesis in Partial Responders? Read More »

Molecular targeted treatment in infants with central conducting lymphatic anomalies

Vera C. van den Brink, Lotte E. R. Kleimeier, Erika K. S. M. Leenders, Willemijn M. Klein, Willem P. de Boode, Joris Fuijkschot, Sabine L. A. G. VranckenAmalia Children’s Hospital, Radboud University Medical Center. Netherlands European Journal of PediatricsEur J Pediatr 2025; 184: DOI: 10.1007/s00431-025-06376-2 AbstractCentral conducting lymphatic anomaly (CCLA) is a rare and potentially life-threatening

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Vardenafil vs. Sildenafil for the Treatment of Persistent Pulmonary Hypertension in Newborns

Sania El-HindiChildren’s Hospital.Syria Indian Journal of PediatricsIndian L Pediatr 2025; DOI: 10.1007/s12098-025-05787-1 AbstractAbstract Not Available CategoryClass I. Persistent Pulmonary Hypertension of the NewbornMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access Free PDF File or Full Text Article

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