Segmental Pulmonary Venous Disease. Without a Focus on Pulmonary Hypertension

In Vitro Models to Study Fibroelastic Remodeling of the Endocardium in Congenital Heart Disease

Julia Gaal, Cindy Zajac, Sophie C. Doettl, Magnus von Piechowski, Kerstin Saraci, Viktoria Weixler, Daniel Diaz-Gil, Pedro J. del Nido, Ingeborg FriehsBoston Children’s Hospital. Charité University. University Hospital of Giessen and Marburg and Justus Liebig University Giessen. Harvard Medical School. United States and Germany Pediatric CardiologyPediatr Cardiol 2026; DOI: 10.1007/s00246-026-04503-w AbstractCongenital heart defects (CHD) are

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Imatinib Mesylate and Sirolimus Inhibit Vascular Fibroproliferative Remodeling in Pulmonary Vein Stenosis

Julia Gaal, Sophie C. Doettl, Kerstin Saraci, Cindy Zajac, Alexa von Mueffling, Peter E. Hammer, Magnus von Piechowski, Verena Gebert, Andrei-Antonio M. Caracioni, Daniel Diaz-Gil, Viktoria Weixler, Pedro J. Del Nido, Kathy Jenkins, Ingeborg FriehsBoston Children’s Hospital and Harvard Medical School. German Heart Center of Charité-Universitätsmedizin Berlin.United States and Germany ChildrenChildren 2026; 13: DOI: 10.3390/children13091280

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A Computational Framework for Quantifying Hemodynamic Burden in Pediatric Pulmonary Vein Stenosis

Manish Bansal, Dan Lior, Avishek Mukherjee, Jeffrey S. Heinle, Athar M. Qureshi, Charles Puelz, Ravi K. BirlaTexas Children’s Hospital and Baylor College of Medicine. University of Houston. United States Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2026; DOI: 10.1016/j.jtcvs.2026.09.007 AbstractBackground: Pulmonary vein stenosis (PVS) is a rare but devastating pediatric disorder characterized by

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Recurrent pulmonary vein stenosis in a pediatric bilateral lung transplant recipient

Timothy Klouda, Francis Fynn-Thompson, Kathy Jenkins, Michael Farias, Christina M. Ireland, Jennifer Mosey, Wai Wong, Saba Sheikh, Christian Benden, Gary VisnerBoston Children’s Hospital and Harvard Medical School.United States Journal of Heart and Lung Transplantation OpenJHLT Open 2026; 14: DOI: 10.1016/j.jhlto.2026.100650 AbstractPulmonary vein stenosis (PVS) is characterized by luminal narrowing from neointimal proliferation, leading to the obstruction

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Pulmonary Venous Decompressing Collaterals: Angiographic Characteristics and Impact on Outcomes in Pediatric Pulmonary Vein Stenosis

Ashish Saini, Hui Huang, Andrew Jergel, Rosemary Gray, Dennis W. Kim, James KuoChildren’s Healthcare of Atlanta and Emory University School of Medicine. United States Pediatric CardiologyPediatr Cardiol 2026; DOI: 10.1007/s00246-026-04350-9 AbstractPediatric pulmonary vein stenosis (PVS) is a rare, progressive condition associated with significant morbidity and mortality. While pulmonary venous decompressing collaterals (PVDC) have been described, their

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Therapeutic Targets for Pediatric Pulmonary Vein Stenosis: Insights from Animal Models

Siqi She, Debao Li, Qi Sun, Lincai YeShanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Children’s Hospital of Fudan University and National Children’s Medical Center. China ChildrenChildren 2026; 13: DOI: 10.3390/children13050677 AbstractPulmonary vein stenosis (PVS) is a rare and devastating condition affecting infants and children, characterized by progressive intimal hyperplasia, myofibroblast proliferation,

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Transcatheter Interventional Options in Pulmonary Vein Stenosis: When to Stent?

Heidi Van Christopher J. Petit, Oliver M. BarryColumbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian Hospital Morgan Stanley Children’s HospitalUnited States Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Ann 2026;DOI: 10.1053/j.pcsu.2026.02.007 AbstractPulmonary vein stenosis (PVS) is a rare and aggressive condition in infants and children,

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Pulmonary Vein Stenosis Medical Therapy: Current and on the Horizon

Mudit Gupta, David B. FrankPerelman School of Medicine at the University of Pennsylvania and Children’s Hospital of PhiladelphiaUnited States Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Ann 2026;DOI: 10.1053/j.pcsu.2026.02.006 AbstractPulmonary vein stenosis (PVS) is a severe vascular obstructive lesion historically associated with poor survival. As outcomes have

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Pathogenesis, Evaluation, and Management of Pulmonary Vein Stenosis: JACC Review Topic of the Week

Trevor Simard, Dhruv Sarma, William R. Miranda, Charles Jain, Jason H. Anderson, Jeremy D. Collins, Abdallah El Sabbagh, Aravdeep Jhand, Tobias Peikert, Guy S. Reeder, Thomas M. Munger, Douglas L. Packer, David R. HolmesMayo Clinic.United States Journal of the American College of CardiologyJ Am Coll Cardiol 2023; 81: 2361-2373DOI: 10.1016/j.jacc.2023.04.016 AbstractPulmonary vein stenosis (PVS) can arise

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Catheter and echocardiographic-focused management of primary pulmonary vein stenosis in premature infants: a single center 5-year experience

Keira Nassetta Conor P. O’Halloran, Emily Hoyt, Matthew Cornicelli, Nicolas Porta, Jeremy Fox, Alan W. Nugent, Paul Tannous, Amanda HauckAnn and Robert H. Lurie Children’s Hospital of Chicago.United States Journal of PerinatologyJ Perinatol 2026;DOI: 10.1038/s41372-026-02611-2 AbstractBackground/objectives: We describe the outcomes of pulmonary vein stenosis treatment in a cohort of premature infants using an assertive percutaneous management strategy

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