Right Heart Dysfunction Associated with Pulmonary Vascular Disease

Functional and molecular determinants of right ventricular response to severe pulmonary hypertension in a large animal model

R. Dale Brown, Kendall S. Hunter, Min Li, Maria G. Frid, Julie Harral, Greta M. Krafsur, Timothy N. Holt, Jason Williams, Hui Zhang, Suzette R. Riddle, Michael G. Edwards, Sushil Kumar, Cheng-Jun Hu, Brian B. Graham, Lori A. Walker, Franklyn B. Garry, Peter M. Buttrick, Tim Lahm, Vitaly O. Kheyfets, Kirk C. Hansen, Kurt R. […]

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The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload

Raquel F. Videira, Anne-Marie C. Koop, Lara Ottaviani, Ella M. Poels, Jordy M. M. Kocken, Cristobal Dos Remedios, Pedro Mendes-Ferreira, Kees W. Van De Kolk, Gideon J. Du Marchie Sarvaas, Andre´ Lourenc, Aida Llucia`-Valldeperas, Diana S. Nascimento, Leon J. De Windt, Frances S. DeMan, Ineˆs Falc~ao-Pires, Rolf M. F. Berger, Paula A. da Costa MartinsMaastricht

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Maternal and fetal outcomes of pregnant women with pulmonary arterial hypertension associated with congenital heart disease in Beijing, China: A retrospective study

Yang Liu, Yanna Li, Jun Zhang, Dawei Zhang, Jiachen Li, Yichen Zhao, Kemin Liu, Xiaolong Ma, Chen Bai, Hong Gu, Xiangming Fan, Jiangang WangBeijing Anzhen Hospital Affiliated to Capital Medical University. China Pulmonary CirculationPulm Circ 2022; 12: DOI: 10.1002/pul2.12079 AbstractAs pulmonary arterial hypertension associated with congenital heart disease (PAH-CHD) may increase maternal and fetal risk, this

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Cardiac Fibrosis in the Pressure Overloaded Left and Right Ventricle as a Therapeutic Target

Katharina Schimmel, Kenzo Ichimura, Sushma Reddy, Francois Haddad, Edda SpiekerkoetterStanford University School of Medicine. United States Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2022; 9: DOI: 10.3389/fcvm.2022.886553 AbstractMyocardial fibrosis is a remodeling process of the extracellular matrix (ECM) following cardiac stress. “Replacement fibrosis” is a term used to describe wound healing in the acute phase of an

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Effects of a Long-Term Wearable Activity Tracker-Based Exercise Intervention on Cardiac Morphology and Function of Patients with Cystic Fibrosis

Maria Anifanti, Stavros Giannakoulakos, Elpis Hatziagorou, Asterios Kampouras, John Tsanakas, Asterios Deligiannis, Evangelia KouidiAristotle University of Thessaloniki and Hippokration Hospital. Greece SensorsSensors 2022; 22: DOI: 10.3390/s22134884 AbstractSeveral studies have shown that patients with cystic fibrosis (CF), even at a young age, have pulmonary and cardiac abnormalities. The main complications are cardiac right ventricular (RV) systolic and/or

Effects of a Long-Term Wearable Activity Tracker-Based Exercise Intervention on Cardiac Morphology and Function of Patients with Cystic Fibrosis Read More »

Metabolic Reprogramming of the Right Ventricle and Pulmonary Arteries in a Flow-Associated Pulmonary Arterial Hypertension Rat Model

Dongli Liu, Suyuan Qin, Danyan Su, Kai Wang, Yanyun Huang, Yuqin Huang, Yusheng PangThe First Affiliated Hospital of Guangxi Medical University. The First Affiliated Hospital of Wenzhou Medical University.China American Chemical Society OmegaACS Omega 2021; 7: 1273-1287DOI: 10.1021/acsomega.1c05895 AbstractPulmonary arterial hypertension (PAH) is a complex devastating disease relevant to remarkable metabolic dysregulation. Although various research studies

Metabolic Reprogramming of the Right Ventricle and Pulmonary Arteries in a Flow-Associated Pulmonary Arterial Hypertension Rat Model Read More »

Development of a PET/MRI exercise stress test for determining cardiac glucose dependence in pulmonary arterial hypertension

Gregory P. Barton, Philip A. Corrado, Christopher J. Francois, James R. Runo, Naomi C. Chesler, Alan B. McMillan, Oliver Wieben, Kara N. GossUniversity of Wisconsin. University of Texas Southwestern Medical Center. University of California-Irvine. United States Pulmonary CirculationPulm Circ 2022; DOI: 10.1002/pul2.12025 AbstractNo Abstract Available CategoryClass I. Pulmonary Hypertension Associated with Connective Tissue DiseasePulmonary Hypertension Associated

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Multiparametric evaluation of right ventricular function in pulmonary arterial hypertension associated with congenital heart disease

Emmanuelle Fournier, Maëlle Selegny, Myriam Amsallem, Francois Haddad, Sarah Cohen, Estibaliz Valdeolmillos, Jérôme Le Pavec, Marc Humbert, Marc-Antoine Isorni, Arshid Azarine, Olivier Sitbon, Xavier Jais, Laurent Savale, David Montani, Elie Fadel, Joy Zoghbi, Emre Belli, Sebastien HascoëtMarie Lannelongue Hospital, Groupe Hospitalier Paris Saint Joseph and Paris-Saclay University. Stanford University School of Medicine. Marie Lannelongue Hospital.

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Comparison between BNP and NT-proBNP in pediatric populations

Kwaku D. Tawiah, Caroline E. Franks, Jessica Tang, Avihu Gazit, Dennis J. Dietzen, Christopher W. FarnsworthWashington University School of Medicine. National Institutes of Health.United States Clinical BiochemistryClin Biochem 2022; 109-110: 74-78DOI: 10.1016/j.clinbiochem.2022.08.003 AbstractBackground: B-type natriuretic peptide (BNP) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are essential biomarkers for the evaluation of cardiac pathologies. However, pediatric reference intervals for

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Alveolar dead space fraction is not associated with early RV systolic dysfunction in pediatric ARDS

Daniel Chilcote, Laura Mercer-Rosa, Yan Wang, Steven M. Kawut, Robert A. Berg, Nadir Yehya, Adam S. HimebauchPerelman School of Medicine at the University of Pennsylvania and Children’s Hospital of Philadelphia. United States Pediatric PulmonologyPediatr Pulmonol 2023; 58: 559-565DOI: 10.1002/ppul.26237 AbstractPrimary hypothesis: We hypothesized that higher alveolar dead space fraction (AVDSf) at pediatric acute respiratory distress syndrome (PARDS)

Alveolar dead space fraction is not associated with early RV systolic dysfunction in pediatric ARDS Read More »

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