Heart Dysfunction Associated with Pulmonary Vascular Disease

Right atrial function is impaired in pediatric pulmonary arterial hypertension: a multi-center cardiac MRI study

Kimberley G. Miles, Hieu T. Ta, Kurt R. Bjorkman, Zhiqian Gao, Nicholas J. Ollberding, Russel Hirsch, D. Dunbar Ivy, Sean M. Lang, Michelle Cash, Melissa Magness, Meredith O’Neil, Kimberly Luebbe, Benjamin S. Frank, Paul J. CritserCincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine. Helen DeVos Children’s Hospital. University of Colorado School

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The Effect of Microvascular Remodeling on Fluid Dynamics in the Pressure Overloaded Right Ventricle

Ilham Essafri, Kenzo Ichimura, Dunbar Ivy, Kurt R. Stenmark, Helena A. Turton, Laura L. Pyle, Edda Spiekerkoetter, Vitaly O. KheyfetsUniversity of Colorado Anschutz Medical Campus and Children’s Hospital Colorado. Stanford University, Stanford. United States American Journal of Physiology Heart and Circulatory PhysiologyAm J Physiol Heart Circ Physiol 2025; DOI: 10.1152/ajpheart.00147.2025 AbstractRight ventricular (RV) failure, a major

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Microvascular preservation & cardiomyocyte hyperplasia underlie adaptive right ventricle development in congenital heart disease-pulmonary arterial hypertension

Michael A. Smith, Eleana S. Guardado, Jason Boehme, Sanjeev A. Datar, Emin Maltepe, Naveen Swami, Gary W Raff, Aaron Bodansky, Prakash Chelladurai, Joseph Moreno, Annelise Prince, Nevan Powers, Guo N. Huang, Vinicio de Jesus Perez, Jeffrey R. FinemanUniversity of California, San Francisco. Stanford University. United States American Journal of Physiology Heart and Circulatory PhysiologyAm J

Microvascular preservation & cardiomyocyte hyperplasia underlie adaptive right ventricle development in congenital heart disease-pulmonary arterial hypertension Read More »

Echocardiographic correlation of right ventricular-Pulmonary artery coupling to exercise tolerance in congenital heart disease-associated pulmonary hypertension

Anudya Kartika Ratri, Ovin Nada Saputri, David Nugraha, Ricardo Adrian Nugraha, Alisia Yuana Putri, Meity Ardiana, Budi Susetyo Pikir, I. Gde Rurus SuryawanUniversitas Airlangga. Dr. Soetomo General Academic Hospital. Indonesia Annals of Pediatric CardiologyAnn Pediatr Cardiol 2025; 18: 26-32DOI: 10.4103/apc.apc_230_24 AbstractBackground: Pulmonary arterial hypertension (PAH) is a chronic, progressive disease affecting the pulmonary vasculature, with a high

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SUL-150 Limits Vascular Remodeling and Ventricular Failure in Pulmonary Arterial Hypertension

Lysanne M. Jorna, Dalibor Nakládal, Johannes N. van Heuveln, Diederik E. van der Feen, Quint A. J. Hagdorn, Guido P. L. Bossers, Annemieke van Oosten, Michel Weij, Ludmila Tkáciková, Sona Tkáciková, Robert H. Henning, Martin C. Harmsen, Rolf M. F. Berger, Guido KrenningUniversity Medical Center Groningen, University of Groningen. Comenius University Bratislava. University of Heidelberg.

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Cardiac function in children with congenital diaphragmatic hernia: cardiac strain at birth and at 2-5 weeks of age

Katarina Övermo Tydén, Kerstin Magnusson, Carmen Mesas Burgos, Baldvin Jonsson, Felicia NordenstamKarolinska Institutet and Karolinska University Hospital.Sweden Frontiers in PediatricsFront Pediatr 2025; 13: DOI: 10.3389/fped.2025.1598695 AbstractIntroduction: Neonates with congenital diaphragmatic hernia (CDH) often present with pulmonary hypertension and various forms of cardiac dysfunction, affecting right or left ventricle or both. Although pulmonary hypertension typically improves over time,

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Long noncoding RNA FGD5-AS1-encoded micropeptides improve right heart functions of pulmonary arterial hypertension through restricting the synthesis of hyaluronic acid

Yijun Chen, Qianhui Zhang, Xi Chen, Yahe Xu, Jing Guo, Jiajia Meng, Mingjie Zhang, Bo Wang, Zhuoming XuShanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine.China International Journal of Biological MacromoleculesInt J Biol Macromol 2025; DOI: 10.1016/j.ijbiomac.2025.146018 AbstractPulmonary arterial hypertension (PAH) is marked by elevated vascular resistance, right ventricular (RV) failure, and poor

Long noncoding RNA FGD5-AS1-encoded micropeptides improve right heart functions of pulmonary arterial hypertension through restricting the synthesis of hyaluronic acid Read More »

Biventricular electromechanical dysfunction and molecular remodeling in a rat model of advanced pulmonary arterial hypertension

Francesco Paolo Lo Muzio, Alessia Caputo, Rosario Statello, Mirko Hu, Roberta Maestri, Giovanna Pelà, Aderville Cabassi, Margherita Burattini, Giacomo Rozzi, Silvia Berrettoni, Barbara Montanini, Stefano Rossi, Lorenzo Fassina, Giovanni Battista Luciani, Gianluigi Condorelli, Michele MiragoliUniversity of Parma. Deutsches Herzzentrum Der Charité, Campus Virchow-Klinikum. University of Verona. University of Pavia. IRCCS Humanitas Research Hospital. Italy and

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Echo-Derived Right Ventricular Strain Identifies Pulmonary Hypertension in Pediatric Ventricular Assist Device Patients

Ryan S. Bishop, Tam T. Doan, Claudia Lara, Lindsay F. Eilers, Hari P. Tunuguntla, Joseph A. Spinner, Ricardo H. Pignatelli, Anitha Parthiban, James C. WilkinsonTexas Children’s Hospital and Baylor College of Medicine.United States American Society for Artificial Internal OrgansASAIO 2025; DOI: 10.1097/MAT.0000000000002489 AbstractIdentifying pulmonary hypertension in pediatric patients with continuous-flow ventricular assist device (cf-VAD) remains challenging,

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Juvenile Systemic Sclerosis Presenting With Severe Pulmonary Vascular Disease: ECMO Stabilization During Aggressive Therapy Resulting in a Favorable Outcome

Stephanie M. Tsoi, Shannon Cheung, Roberto Alejandro Valdovinos, Elena Amin, Hythem Nawaytou, Elizabeth Colglazier, Claire Parker, April Edwell, Susan Kim, Jeffrey R. FinemanUniversity of California San Francisco. Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70106 AbstractJuvenile systemic sclerosis (jSSc) associated pulmonary hypertension (PH) is rare, but, the leading cause of morbidity and mortality in jSSc. This is

Juvenile Systemic Sclerosis Presenting With Severe Pulmonary Vascular Disease: ECMO Stabilization During Aggressive Therapy Resulting in a Favorable Outcome Read More »

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