Heart Dysfunction Associated with Pulmonary Vascular Disease

Contemporary treatment of right ventricular failure

Bibhuti B. Das, Shashi RajUniversity of Mississippi Medical Center. Narayana Health.United States and India Journal of Heart and Lung Transplantation OpenJHLT Open 2025; 7: DOI: 10.1016/j.jhlto.2024.100203 AbstractRight ventricular failure (RVF) is a clinical syndrome resulting from structural and functional changes in the right ventricle (RV), leading to inadequate blood flow to the pulmonary circulation and elevated […]

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Homeostatic Role of Decorin in Right Ventricular Pressure Overload and Pulmonary Hypertension Induced Remodeling

Yohei Akazawa, Sriram Vaidyanathan, Michael Bradley Dewar, Kana Yazaki, John Dauz, Osami Honjo, Mei Sun, Golam Kabir, Robert P. Jankov, Scott Patrick Heximer, Kim A. Connelly, Mark K. FriedbergHospital for Sick Children and University of Toronto. Stanford University. St. Michael’s Hospital. Children’s Hospital of Eastern Ontario Research Institute.Canada and United States Journal of the American

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Right Atrial Dysfunction Is Prevalent in Pediatric Acute Respiratory Distress Syndrome and Reflects Pulmonary Hypertension and Right Ventricular Dysfunction

Nathan D. Markiewitz, Yan Wang, Robert A. Berg, Nadir Yehya, Celeste Dixon, Laura Mercer-Rosa, Adam S. HimebauchChildren’s Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania. United States Critical Care ExplorationsCrit Care Exp 2025; 7: DOI: 10.1097/CCE.0000000000001230 AbstractImportance: Right atrial (RA) dysfunction is associated with worse outcomes in some populations with pulmonary hypertension

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Characterization of Intracardiac Flow in the Right Ventricle With Pressure and Volume Overload in Children

Yasunobu Hayabuchi, Yukako HommaTokushima University.Japan Cardiology ResearchCardiol Res 2025; 16: 22-32DOI: 10.14740/cr2009 AbstractBackground: Blood flow visualization using vector flow mapping (VFM) holds potential as a novel indicator of right ventricular (RV) function.Methods: This study included 12 patients with atrial septal defect (ASD group, mean (± standard deviation) age: 6.2 ± 1.5 years), six patients with pulmonary hypertension (PH

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Novel Therapies for Right Ventricular Failure

Bibhuti B. DasUniversity of Mississippi Medical Center.United States Current Cardiology ReportsCurr Cardiol Rep 2025; 27:DOI: 10.1007/s11886-024-02157-9 AbstractPurpose of review: Traditionally viewed as a passive player in circulation, the right ventricle (RV) has become a pivotal force in hemodynamics. RV failure (RVF) is a recognized complication of primary cardiac and pulmonary vascular disorders and is associated with a

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Mortality Patterns in Pediatric Pulmonary Vein Stenosis: Insights Into Right Ventricular Systolic Pressure Associations

Daiji Takajo, Paul J. Critser, Michelle Cash, Melissa Magness, Russel HirschCincinnati Children’s Hospital Medical Center and University of Cincinnati.United States Journal of the American Heart AssociationJ Am Heart Assoc 2025; DOI: 10.1161/JAHA.124.037908DOI: 10.1161/JAHA.124.035037 (correction) AbstractBackground: Pulmonary vein stenosis in children is associated with a poor prognosis. However, the cause and risk factors for mortality remain uncertain.Methods: This retrospective, single-center

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Pediatric Pulmonary Arterial Hypertension; is it Possible to Predict its Outcome?

Hala M. Aghaa, Ranya Hegazy, Ahmed Gamal, Ranya Essam, Antoine A. Elmessih, Ahmed Behairy,Nagib Dahdah, Ahmed Abdelwahed, Nesrine Sobhy, Noha AliSpecialized Pediatric Hospital and Cairo University. CHU Sainte Justine and University of Montreal.Egypt and Canada Journal of the Saudi Heart AssociationJ Saudi Heart Assoc 2024; 36: 408-419DOI: 10.37616/2212-5043.1398 AbstractObjectives: To assess the outcome of pediatric pulmonary arterial

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Use of Right Ventricular Free-Wall Strain in a Multivariable Estimate of Right Ventricular-Arterial Coupling in Pediatric Pulmonary Arterial Hypertension

Charles T. Simpkin, D. Dunbar Ivy, Mark K. Friedberg, Dale A. BurkettChildren’s Hospital Colorado and University of Colorado – Anschutz Medical Campus. Hospital for Sick Children and University of Toronto.United States and Canada Circulation Cardiovascular ImagingCirc Cardiovasc Imag 2024; DOI: 10.1161/CIRCIMAGING.124.016882 AbstractBackground: Right ventricular-arterial coupling (RVAC) describes the relationship between right ventricular contractility and pulmonary vascular afterload.

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Echocardiographic Changes in Infants with Severe Congenital Diaphragmatic Hernia After Fetoscopic Endoluminal Tracheal Occlusion (FETO)

Catherine M. Avitabile, Sabrina Flohr, Leny Mathew, Yan Wang, Devon Ash, Juliana S. Gebb, Natalie E. Rintoul, Holly L. HedrickUniversity of Pennsylvania Perelman School of Medicine and Children’s Hospital of Philadelphia. United States Pediatric CardiologyPediatr Cardiol 2024; DOI: 10.1007/s00246-024-03735-y AbstractFetoscopic endoluminal tracheal occlusion (FETO) induces lung growth and may improve survival in congenital diaphragmatic hernia (CDH)

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Asymmetric right ventricular myocardial work correlates with gold standard measurements of cardiac function in pulmonary hypertension

Simone G. Diab, Ryota Ebata, Dariusz Mroczek, Wei Hui, Espen W. Remme, Thomas Möller, Mark K. FriedbergOslo University Hospital and University of Oslo. Chiba University. Hospital for Sick Children.Norway and Japan Pulmonary CirculationPulm Circ 2024; 14: DOI: 10.1002/pul2.70014 AbstractRight ventricular (RV) (dys)function determines outcomes in pulmonary hypertension (PH). We previously found that asymmetric RV myocardial work

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