Heart Dysfunction Associated with Pulmonary Vascular Disease Archives

Myocardial work during various right ventricle load conditions in a paediatric population

Ramona Ghenghea, Pierrick Pyra, Yves Dulac, Aitor Guitarte, Paul Vignaud, Philippe Acar, Khaled Hadeed, Clement KarsentyChildren’s Hospital, CHU Toulouse and Paul Sabatier University. France Achives of Cardiovascular DiseaseArch Cardiovasc Dis 2026; DOI: 10.1016/j.acvd.2025.11.013 AbstractBackground: Assessing right ventricular (RV) function in children is challenging, particularly in RV overload, where conventional echocardiographic indices do not account for afterload.Aims: This prospective […]

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Pathophysiology and prevalence of high output heart failure in group 1 pulmonary hypertension

Yogesh N V Reddy 1, Robert P Frantz 2, William R Miranda 2, Revati Varma 2, Paul M Hassoun 3, Anna R Hemnes 4, Evelyn Horn 5, Jane A Leopold 6, Franz Rischard 7, Erika B Rosenzweig 8, Nicholas S Hill 9, Serpil C Erzurum 10, Gerald J Beck 11, Samar Farha 12, J Emanuel Finet 12, Christine Jellis 12, Deborah Kwon 12, Stephen Mathai 3, Margaret Park 12, W H Wilson Tang 12, Barry A Borlaug 2; PVDOMICS Study GroupMayo Clinic. Johns Hopkins University. Vanderbilt University Medical Center. Weill Cornell Medicine. Brigham and Women’s Hospital and

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Current State of RV Multimodality Imaging in Pediatric Pulmonary Hypertension: Current Evidence, Knowledge Gaps, and Future Research Directions

Kimberley G. Miles, Dan M. Dorobantu, Johannes Menno Douwes, Benjamin S. Frank, Pei-Ni Jone, Vivek Muthurangu, D. Dunbar Ivy, Hythem Nawaytou, Mark K. FriedbergCincinnati Children’s Hospital and University of Cincinnati College of Medicine. Bristol Royal Hospital for Children and Heart Institute. Beatrix Children’s Hospital, University Medical Center Groningen and University of Groningen. University of Colorado Denver Anschutz

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Right ventricular adaptation in congenital heart disease: Does the type of right ventricular overload matter?

Renee S. Joosen, Gregor J. Krings, Heleen B. van der Zwaan, Nefise Karaman, Marco Guglielmo, Lucas R. Celant, Marco J. W. G€otte, Michael G. Dickinson, Michiel Voskuil, Marielle C. van de Veerdonk, Johannes M. P. J. BreurUniversity Medical Center Utrecht. Amsterdam University Medical Center and University of Amsterdam. Netherlands Journal of Thoracic and Cardiovascular Surgery

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AI learning for pediatric right ventricular assessment: development and validation across multiple centers

Charitha Reddy, Yi Yan, Min Qiu, Yi Tang, Bo Jin, Zhi Han, Yuhang Li, Sihan Zhou, Qiming Tang, Huan Xiao, Shu Yang, Qigui Wen, Lan-Ping Wu, Li-Jun Fu, Ze-Yu Jing, Yi-Jia Yang, Yu-Qi Zhang, Naoto Ozawa, Takumi Ichikawa, Ellen Ling, Ronald J. Wong, Nima Aghaeepour, Brice Gaudilliere, Martin S. Angst, Karl G. Sylvester, Harvey J.

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Paediatric pulmonary arterial hypertension following congenital heart defect repair: Enhanced risk stratification and outcomes in a national cohort

Andrew Constantine, Konstantinos Dimopoulos, Robin Condliffe, Paul Clift, Katrijn Jansen, S. John Wort, Grace Chaplin, Kaushiga Krishnathasan, Rami Dhillon, Joydeep Mookerjee, W. Brodie Knight, Caroline B. Jones, Maria N. Velasco Forte, Dirk Wilson, Helen Michael, Alberto Mendoza Soto, Carlos Labrandero, Alejandro Rodríguez Ogando, Antonio Moreno Galdó, Inmaculada Guillén Rodríguez, Lina M. Caicedo Cuenca, Francesca Perin,

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Use of SGLT2 (Sodium-Glucose Cotransporter 2) Inhibitors in Pulmonary Hypertension

Benoit Aguado, Grégoire Ruffenach, Thomas Lacoste-Palasset, Agnes Görlach, Marianne Riou, Mathieu Gourmelon, Fabrice Bauer, Marc Humbert, Valerie Schini-Kerth, Jean-Luc Vachiéry, David Montani, Fabrice AntignyUniversité Paris-Saclay and French National Institute for Health and Medical Research. Hôpital Bicêtre and Hôpital Marie Lannelongue. Technical University Munich and German Centre for Cardiovascular Research. Nouvel Hôpital Civil and University Hospital

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Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Li-Wei Wu, Min Chen, Chen-Yu Jiang, Dai-Ji Jiang, Xu Zhang, Xiao-He Xu, Yi-Wei Liu, Bei Feng, Lin-Cai Ye, Yang-Yang He, Xu Huang, Yi-Chi Zhang, Xing-Liang Zhou, Yi Shen, Tian-Yu Liu, Li-Jun Fu, Yi Yan, Hao ZhangShanghai Children’s Medical Center, National Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Second Affiliated Hospital and

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Volume Loading May Compromise Left Ventricular Filling in Patients with a Borderline Hypoplastic Left Ventricle

Machi Yamashita, Hirofumi Saiki, Kanchi Saito, Akira Sato, Seiko Kuwata, Satoshi Nakano, Hideaki Senzaki, Junichi KoizumiIwate Medical University. Nihon Institute of Medical Science.Japan International Heart JournalInt Heart J 2025; 66: 1019-1024DOI: 10.1536/ihj.25-216 AbstractGiven the high prevalence of end-organ damage in the long term after the Fontan procedure, patients presenting with borderline hypoplastic left ventricle (LV) are

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Longitudinal changes of left ventricular hypoplasia and ventricular disproportion in congenital diaphragmatic hernia neonates

Flaminia Pugnaloni, Bartolomeo Bo, Judith Leyens, Irma Capolupo, Andrea Dotta, Pietro Bagolan, Andreas Mueller, Neil Patel, Florian KipfmuellerChildren’s Hospital, University Hospital Bonn and University of Bonn. Bambino Gesù Children’s Hospital-Research Institute, IRCCS. University Medical Center, Mannheim and Heidelberg University. University of Rome “Tor Vergata”. Royal Hospital for Children. Germany, Italy and United Kingdom Journal of

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