Class 1. Pulmonary Hypertension Associated With Infection

Covid-19-induced pulmonary hypertension in children, and the use of phosphodiesterase-5 inhibitors

Herlina Dimiati Dimas Arya Umara, Iflan NaufalUniversitas Syiah Kuala,Indonesia F1000 ResearchF1000Res 2022; DOI: 10.12688/f1000research.53966.2 AbstractRespiratory tract infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first occurred in Wuhan, China, in December 2019 and was declared as a pandemic by WHO. The interaction between the 2019 coronavirus disease (COVID-19) and pulmonary hypertension (PH) in children […]

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Biological impact of manual blood exchange in malignant Bordetella pertussis infection in infants

Vladimir L. Cousin, Caroline Caula, Pierre TissieresAssistance Publique des Hôpitaux de Paris and Paris Saclay University and Bicêtre Hospital. Geneva University Hospital. Hôpital Robert-Debré. France and Switzerland Vox SanguinisVox Sang 2024; DOI: 10.1111/vox.13722 AbstractBackground and objectives: Manual blood exchange (MBE) is a leukoreduction therapy for hyperleukocytosis in Bordetella spp.Infection: We describe the impact of BE on clinical and

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The Epidemic of Congenital Syphilis in the Indigenous and Rural Populations of South Dakota

Narysse Nicolet, Amrita Bhagia, Megan Torve, Kessa Tribby, Nicole Poppinga, Kimberlee McKay, Maria M. Talavera-BarberUniversity of South Dakota Sanford School of Medicine. Monument Health. Avera McKennan Hospital and University Health CenterUnited States PediatricsPediatrics 2024; DOI: 10.1542/peds.2023-063823 AbstractFrom 2020 to 2023, South Dakota witnessed a substantial increase in cases of congenital syphilis (CS), with the highest rates

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Multisystem Inflammatory Syndrome in Neonates Associated with COVID-19 in Neonatal ICU of a Tertiary Care Hospital

Asma Shabbir, Humaira Khurshid, Imran Mahmood KhanFazaia Medical College, Pakistan Air Force Hospital.Pakistan Journal of the College of Physicians and Surgeons PakistanJ Coll Physicians Surg Pak 2024; 34: 727-731 DOI: 10.29271/jcpsp.2024.06.727 AbstractObjective: Neonatal multisystem inflammatory syndrome (MIS-N) is a unique disease of neonates described in several case reports from all over the world with a myriad of

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Interstitial macrophage phenotypes in Schistosoma-induced pulmonary hypertension

Rahul Kumar, Sushil Kumar, Claudia Mickael, Dara Fonseca Balladares, Kevin Nolan, Michael H. Lee, Linda Sanders, Julia Nilsson, Ari B. Molofsky, Rubin M. Tuder, Kurt R. Stenmark, Brian B. GrahamUniversity of California, San Francisco and Zuckerberg San Francisco General Hospital. University of Colorado Anschutz Medical Campus. United States Frontiers in ImmunologyFront Immunol 2024; DOI: 10.3389/fimmu.2024.1372957 AbstractBackground: Schistosomiasis

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A case report of a child with pulmonary hypertension associated with SARS-CoV-2 infection

Kentaro Okunushi, Hironobu Kobayashi, Yuri Yoh, Masaya Kunimatsu, Tadashi Shiohama, Tomozumi Takatani, Hiromichi HamadaChiba University.Japan Frontiers in PediatricsFront Pediatr 2024; 12:DOI: 10.3389/fped.2024.1336589 AbstractWe encountered a pediatric case of pulmonary hypertension triggered by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. A 14-year-old girl was brought to the emergency department of our hospital with fever, respiratory distress,

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Long-term outcomes and immune profiling in children with multisystem inflammatory syndrome (MIS-C)

Indira Jaxybayeva, Riza Boranbayeva, Minira Bulegenova, Natalya Urazalieva, Valentin Gerein, Lyazat ManzhuovaAsfendiyarov Kazakh National Medical University. Goethe University Hospital.Kazakhstan and Germany Acta BiomedicaActa Biomed 2023;DOI: 10.23750/abm.v94i6.14788 AbstractBackground and aim: Existing follow-up data after MIS-C is limited.Purpose of the study: to investigate the long-term consequences in children who have undergone MIS-C.Methods: The retrospective study included 93 children. The identified changes

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Neonatal sepsis and cardiovascular dysfunction I: mechanisms and pathophysiology

Sophie M. Duignan, Satyan Lakshminrusimha, Kathryn Armstrong, Willem P. de Boode, Afif El-Khuffash, Orla Franklin, Eleanor J. Molloy, Infection, Inflammation, Immunology and Immunisation Section of the European Society for Pediatric Research (ESPR)Children’s Health Ireland at Crumlin. University of California, Davis Children’s Hospital. British Columbia Children’s Hospital. Radboud University Medical Center and Amalia Children’s Hospital. Royal

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Atypical Hemolytic-Uremic Syndrome: Genetic Basis, Clinical Manifestations, and a Multidisciplinary Approach to Management

Keval Yerigeri, Saurav Kadatane, Kai Mongan, Olivia Boyer, Linda LG Burke, Sidharth Kumar Sethi, Christoph Licht, Rupesh RainaCase Western Reserve University and The MetroHealth System. University of Oklahoma Health Sciences Center. Northeast Ohio Medical University. Necker-Enfants Malades Hospital. Kidney and Urology Institute. University of Toronto. Akron Children’s Hospital.United States, France and Canada Journal of Multidisciplinary

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Impaired cell-cell communication and axon guidance because of pulmonary hypoperfusion during postnatal alveolar development

Debao Li, Jing Wang, Yuan Fang, Yuqing Hu, Yingying Xiao, Qing Cui, Chuan Jiang, Sijuan Sun, Hao Chen, Lincai Ye, Qi SunShanghai Children’s Medical Center. Shanghai Jiao Tong University. Shanghai Ninth People’s Hospital. China Respiratory ResearchRespir Res 2023; 24: DOI: 10.1186/s12931-023-02319-3 AbstractBackground: Pulmonary hypoperfusion is common in children with congenital heart diseases (CHDs) or pulmonary hypertension (PH)

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