Class 3. Pulmonary Hypertension Associated with Alveolar Hypoxia

Adenylyl Cyclase Isoform 6 in the Pulmonary Artery Is Inhibited by Hypoxia via Cysteine Nitrosylation

Saeid Maghsoudi, Vikram Bhatia, Martha Hinton, Nisha Singh, Modh Wasif Khan, Prashen Chelikani, Shyamala, DakshinamurtiUniversity of Manitoba Faculty of Health Sciences. University of Manitoba Children’s Hospital Research Institute of Manitoba. University of Manitoba College of Dentistry. Canada American Journal of Respiratory Cell and Molecular BiologyAm J Respir Cell Mol Biol 2024; DOI: 10.1165/rcmb.2023-0447OC AbstractPersistent pulmonary hypertension […]

Adenylyl Cyclase Isoform 6 in the Pulmonary Artery Is Inhibited by Hypoxia via Cysteine Nitrosylation Read More »

Lipocalin-2 induced LDHA expression promotes vascular remodelling in pulmonary hypertension

Yao Yao, Xin Bin, Yanxuan Xu, Shaowan Chen, Si Chen, Xiang-Ling Yuan, Yingjie Cao, Tsz Kin NgBeijing Children’s Hospital, Capital Medical University and National Center for Children’s Health. Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College. Beijing Children’s Hospital and Capital Medical University. Chinese Academy of

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[Protective effects of 2-methoxyestradiol against hypoxic pulmonary hypertension in neonatal rats]

Ou Xie, Shan-Shan Li, Yang Luo, Le WangFirst Affiliated Hospital of Xinjiang Medical University.China Chinese Journal of Contemporary PediatricsZhongguo Dang Dai Er Ke Za Zhi 2024; 26: 757-764DOI: 10.7499/j.issn.1008-8830.2401078 AbstractObjectives: To investigate the protective effects of 2-methoxyestradiol (2ME) against hypoxic pulmonary hypertension (HPH) in neonatal rats.Methods: Ninety-six Wistar neonatal rats were randomly divided into a normoxia group, a

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Pharmacological Gq inhibition induces strong pulmonary vasorelaxation and reverses pulmonary hypertension

Alexander Seidinger, Richard Roberts, Yan Bai, Marion Müller, Eva Pfeil, Michaela Matthey, Sarah Rieck, Judith Alenfelder, Gabriele M. KUonig, Alexander Pfeifer, Evi Kostenis, Anna Klinke, Bernd K. Fleischmann, Daniela WenzelUniversity Hospital of the Ruhr University of Bochum and Ruhr University of Bochum. University Hospital of Nottingham. Massachusetts General Hospital and Harvard Medical School. University of

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Letter to the Editor: T-Wave Inversion in Leads V1-V3 as a Crucial Indicator of High-Altitude Pulmonary Hypertension among Young Chinese Males at 4,820 m: A Report of Two Cases

Xu-Gang Tang, Zheng-Dao Wei, Xiao Wang, Rui Zhang, Jing Wen, De LiGeneral Hospital of Western Theater Command. People’s Hospital of Hechuan District.China High Altitude Medicine and BiologyHigh Alt Med Biol 2024; DOI: 10.1089/ham.2024.0093 AbstractAbstract Not Available CategoryClass III. Pulmonary Hypertension Associated with Alveolar HypoxiaDiagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing Age Focus: Pediatric Pulmonary Vascular

Letter to the Editor: T-Wave Inversion in Leads V1-V3 as a Crucial Indicator of High-Altitude Pulmonary Hypertension among Young Chinese Males at 4,820 m: A Report of Two Cases Read More »

Achieved oxygen saturations and risk for bronchopulmonary dysplasia with pulmonary hypertension in preterm infants

Samuel J. Gentle, Avinash Singh, Colm P. Travers, Arie Nakhmani, Waldemar A. Carlo, Namasivayam AmbalavananUniversity of Alabama at Birmingham.United States Archives of Disease in ChildhoodArch Dis Child 2024; DOI: 10.1136/archdischild-2024-327014 AbstractObjective: Characterisation of oxygen saturation (SpO2)-related predictors that correspond with both bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) development and survival status in infants with BPD-PH may improve patient outcomes.

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Case Report: unexpected cause of cyanosis in an infant after acute exposure to high altitude-severe tricuspid regurgitation secondary to tricuspid valve prolapse

Yaru Cui, Lixia Yang, Ping Wu, Shuran Shao, Shuhua Luo, Kaiyu Zhou, Xiaoliang Liu, Chuan Wang, Hongyu DuanWest China Second University Hospital and Sichuan University. China Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2024; 11: DOI: 10.3389/fcvm.2024.1335218 AbstractBackground: Severe tricuspid regurgitation (TR) causing cyanosis with patent foramen ovale (PFO) and right-to-left atrial shunting requires a precise diagnosis for

Case Report: unexpected cause of cyanosis in an infant after acute exposure to high altitude-severe tricuspid regurgitation secondary to tricuspid valve prolapse Read More »

Post-treatment with Resolvin D1 attenuates pulmonary hypertension by inhibiting endothelial-to-mesenchymal transition

Xinyu Lia, Hui Li, Bo Feng, Xiaoyan Chen, Ting Chen, Jiafei Lu, Huating Xie, Nana Su, Houlin Chen, Chenghao Lou, Runxin Zhuang, Xi Chen, Shengwei Jin, Yu HaoSecond Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University. Ruijin Hospital and Shanghai Jiao Tong University School of Medicine. China Biomedicine and PharmacotherapyBiomed Pharmacother 2024; DOI: 10.1016/j.biopha.2024.117023

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NLRP3 Inflammasome Triggers Inflammation of Obstructive Sleep Apnea

Xiaoting Yangzhong, Shu Hua, Yiqiong Wen, Xiaoqing Bi, Min Li, Yuanyuan Zheng, Shibo SunFirst Affiliated Hospital, Kunming Medical University.China Current Molecular MedicineCurr Mol Med 2024; DOI: 10.2174/0115665240294605240426123650 AbstractObstructive sleep apnea [OSA] is widespread in the population and affects as many as one billion people worldwide. OSA is associated with dysfunction of the brain system that controls

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Effect of Estrogen Receptor Alpha on Cardiopulmonary Adaptation to Chronic Developmental Hypoxia in a Rat Model

Nicholas T. Severyn, Patricia Esparza, Huanling Gao, Elizabeth A. Mickler, Marjorie E. Albrecht, Amanda Fisher, Bakhtiyor Yakubov, Todd G. Cook, James E. Slaven, Avram D. Walts, Robert S. Tepper, Tim LahmUniversity of Kentucky. Indiana University – Purdue University Indianapolis. University of Colorado. National Jewish Health.United States American Journal of Physiology Lung Cellular and Respiratory PhysiologyAm

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