Potential Biomarkers Associated with Pulmonary Vascular Disease

Circulating Intercellular Adhesion Molecule as a Novel Marker of Pulmonary Hypertension in Newborn

Antoine Fakhry AbdelMassih, Sherif ElAnwary, Nourhan Taha, Noha Radwan, Mahmoud Othman AbouDeifCairo University Children Hospital and Cairo University. Sheikh Khalifa Medical City. Egypt and United Arab Emirates Indian PediatricsIndian Pediatr 2025;DOI: 10.1007/s13312-025-00037-1 AbstractBackground: IntercellularAQ1 adhesion molecules (ICAMs) are released from the endothelium in response to shear stress. Their role in persistent pulmonary hypertension (PPHN) remains un-investigated.Methodology: Sixty neonates […]

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Pediatric Pulmonary Hypertension is Associated With Increased Circulating Levels of BMP 7 and CHIP

Edward C. Kirkpatrick, Stephanie Handler, Melodee Liegl, Amy Y. Pan, G. Ganesh Konduri, Todd M. Gudausky, Adeleye J. AfolayanChildren’s Wisconsin and Medical College of Wisconsin.United States Pulmonary CirculationPulm Circ 2024; 15: DOI: 10.1002/pul2.70068 AbstractPulmonary arterial endothelial and smooth muscle cell homeostasis is regulated through the bone morphogenetic protein (BMP) and transforming growth factor beta (TGF-β) receptor

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Cellular Communication Network Protein 2 in the Right Ventricle of Pulmonary Arterial Hypertension

Carly E. Byrd, Jennifer E. Schramm, Jun Yang, Allan E. Barnes, Megan Griffiths, Anjira S. Ambade, Darin T. Rosen, Ilton M. Cubero Salazar, Catherine E. Simpson, Ryan J. Tedford, Steven Hsu, Dhananjay Vaidya, Todd M. Kolb, Michael W. Pauciulo, William C. Nichols, David D. Ivy, Eric D. Austin, Paul M. Hassoun, Rachel L. Damico, Allen

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Increased circulating Endothelin-1 is a risk factor for ECMO use and mortality in neonates with congenital diaphragmatic hernia: a prospective observational study

Lotte Lemloh, Aster de Vadder, Tamene Melaku, Bartolomeo Bo, Neil Patel, Stefan Holdenrieder, Andreas Mueller, Florian KipfmuellerChildren’s Hospital, University of Bonn. Royal Hospital for Children. Technical University of Munich. University Medical Center Mannheim, University of Heidelberg.Germany and United Kingdom Respiratory ResearchRespir Res 2025; 25: DOI: 10.1186/s12931-025-03188-8 AbstractBackground: Elevated levels of Endothelin-1 (ET-1), a vasoactive peptide, have been

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Increased Endothelin-1 Is Associated With Morbidity in Single Ventricle Heart Disease in Children Undergoing Fontan Palliation

Benjamin S. Frank, Sierra Niemiec, Ludmila Khailova, Christopher A. Mancuso, Max B. Mitchell, Gareth J. Morgan, Mark Twite, Michael V. DiMaria, Carmen C. Sucharov, Jesse A. DavidsonUniversity of Colorado. University of Michigan.United States Journal of the American College of Cardiology AdvancesJACC Adv 2025; 4: DOI: 10.1016/j.jacadv.2025.101672 AbstractBackground: Endothelin-1 (ET1) is a potent vasoconstrictor and stimulator of pulmonary

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Corrigendum to “Relationship Between Urine Serotonin and Persistent Pulmonary Hypertension of the Newborn”. J Pediatr 2025; 276:114290

Jamie L. Archambault, Teri L. Hernandez, Eva S. Nozik, Claire Palmer, Mairead Dillon, Ravinder J. Singh, Csaba Galambos, Cassidy A. DelaneyUniversity of Colorado. Mayo Clinic College of Medicine. United States Journal of PediatricsJ Pediatr 2025; DOI: 10.1016/j.jpeds.2025.114462 AbstractAbstract Not Available CategoryClass I. Persistent Pulmonary Hypertension of the NewbornAcquired Patient Factors Associated with Pulmonary Vascular DiseasePotential Biomarkers

Corrigendum to “Relationship Between Urine Serotonin and Persistent Pulmonary Hypertension of the Newborn”. J Pediatr 2025; 276:114290 Read More »

Anti-fibroblast and anti-endothelial cell autoantibodies in pulmonary arterial hypertension (PAH) in patients with connective tissue diseases (CTD)

Benjamin Thoreau, Arthur Ranaud, Philippe Chafey, Guilhem Clary, Morgane La Gall, Cédric Broussard, Odile Launay, David Launay, Eric Hachulla, Christophe Deligny, Alban-Elouen Baruteau, Anaïs Vallet-Pichard, Benjamin Chaigne, Azzeddine Yaici, Oliver Sitbon, David Montani, Marc Humbert, Luc MouthonUniversité Paris Cité. Hôpital Cochin and Assistance Publique-Hôpitaux de Pari. de l’Est et de l’Ouest. Hôpital Pierre Zobda-Quitman. Nantes

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Pediatric Pulmonary Arterial Hypertension; is it Possible to Predict its Outcome?

Hala M. Aghaa, Ranya Hegazy, Ahmed Gamal, Ranya Essam, Antoine A. Elmessih, Ahmed Behairy,Nagib Dahdah, Ahmed Abdelwahed, Nesrine Sobhy, Noha AliSpecialized Pediatric Hospital and Cairo University. CHU Sainte Justine and University of Montreal.Egypt and Canada Journal of the Saudi Heart AssociationJ Saudi Heart Assoc 2024; 36: 408-419DOI: 10.37616/2212-5043.1398 AbstractObjectives: To assess the outcome of pediatric pulmonary arterial

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Independent prognostic value of lipocalin-2 in congenital heart disease-associated pulmonary artery hypertension

Zhang-Ke Guo, Ping-Gui Chen, Yao-Xuan Li, Hong Jiao, Xiao-Hui Kong, Song Bai, Xiao-Feng Li, Ai-Jun Liu, Guo-Liang WangBeijing Children’s Hospital, Capital Medical University, Beijing Anzhen Hospital and National Center for Children’s Health. Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital and Shanxi Academy of Medical Sciences. China World Journal of CardiologyWorld J Cardiol 2024;

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Alterations in Mitochondrial Function in Pulmonary Vascular Diseases

Samar Farha, Kewal Asosingh, Paul M. Hassoun, John Barnard, Suzy Comhair, Andrew Reichard, Nicholas Wanner, Milena Radeva, Micheala A. Aldred, Gerald J. Beck, Erika Berman-Rosenzweig, Barry A. Borlaug, J. Emanuel Finet, Robert P. Frantz, Gabriele Grunig, Anna R. Hemnes, Nicholas Hill, Evelyn M. Horn, Chistine Jellis, Jane A. Leopold, Reena Mehra, Margaret M. Park, Franz

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