Pediatric Pulmonary Vascular Disease

Prospective Evaluation of Pulse Oximetry Screening for Critical Congenital Heart Disease in a Jordanian Tertiary Hospital: High Incidence and Early Detection Challenges

Naser Aldain A. Abu Lehyah, Abeer A. Hasan, Mahmoud Y. Abbad, Razan A. Al-Jammal, Moath K. Al Tarawneh, Dima Abu Nasrieh, Haneen A. Banihani, Saif N. Aburumman, Areen G. Fraijat, Heba M. Alhawamdeh, Qasem A. Shersheer, Milad Kh. Al-Awawdeh, Scott O. Guthrie, Joseph R. StarnesWomen’s and Children’s Hospital of Al Bashir Hospitals. King Abdullah University […]

Prospective Evaluation of Pulse Oximetry Screening for Critical Congenital Heart Disease in a Jordanian Tertiary Hospital: High Incidence and Early Detection Challenges Read More »

Extremely rare association: Desbuquois dysplasia type 1 with coronary-cameral fistula

Musa Öztürk, Hayrettin Hakan Aykan, Pelin Özlem Şimşek KiperHacettepe University Hospital.Turkey Cardiology in the YoungCardiol Young 2025; DOI: 10.1017/S1047951125000551 AbstractPurpose: Desbuquois dysplasia type 1 is a rare autosomal recessive chondrodysplasia characterised by distinct skeletal abnormalities and multisystem involvement, including pulmonary, renal, and ocular abnormalities, has also been reported. Cardiac complications, although infrequently discussed in the literature, include

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Characteristics associated with death or tracheostomy in infants with bronchopulmonary dysplasia following predominant non-invasive respiratory support

Heidi Morris, Megan Reilly, Huayan Zhang, Xiaoyue Dong, Kathleen Gibbs, Catherine M. Avitabile, Sara B. DeMauro, Nicolas A. BamatChildren’s Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine. Guangzhou Women and Children’s Medical Center.United States and China Journal of PerinatologyJ Perinatol 2025; DOI: 10.1038/s41372-025-02234-z AbstractObjective: Identify characteristics associated with death or tracheostomy (D/T) in preterm infants with bronchopulmonary dysplasia (BPD)

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Developing a Neonatal Pulmonary Hypertension Core Outcome Set (NeoPH COS)-A Study Protocol

Cara Ellen Morgan, Kerry Woolfall, Natasharazia Aikman, Crhistopher Gale, Nimish Subhedar, the RePHyNeConsortiumLiverpool Women’s NHS Trust and Univeristy of Liverppool. Imperial College London.United Kingdom Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70052 AbstractPulmonary hypertension (PH) in newborn babies is a relatively rare, heterogeneous condition that has high associated mortality in the neonatal period and beyond. There are

Developing a Neonatal Pulmonary Hypertension Core Outcome Set (NeoPH COS)-A Study Protocol Read More »

RNA-Seq and ChIP-Seq Identification of Unique and Overlapping Target Genes and Pathways Regulated by TBX4 in Human Pulmonary Fibroblasts and Pericytes

Ying Cai, Ling Yan, James West, Joy D. Cogan, Lora K. Hedges, Bethany Nunley, Nick Negretti, Jennifer M. S. Sucre, Eric D. Austin, Rizwan HamidVanderbilt University Medical Center Nashville. Biodevelopment Origins of Lung Disease (BOLD) Center. United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70058 AbstractTranscription factor TBX4 rare variants associate with pulmonary arterial hypertension (PAH), particularly in

RNA-Seq and ChIP-Seq Identification of Unique and Overlapping Target Genes and Pathways Regulated by TBX4 in Human Pulmonary Fibroblasts and Pericytes Read More »

Severe Precapillary Pulmonary Hypertension and Right Ventricular Failure After Hematopoietic Stem Cell Transplantation: Successful Outcomes With Aggressive Upfront Triple Therapy

Stine Andersen, Jesper Vandborg Bjerre, Karin Baekgaard, Lars Idorn, Mads Jønsson AndersenAarhus University Hospital and Aarhus University. Copenhagen University Hospital.Denmark Pediatric Blood and CancerPediatr Blood Cancer 2025; DOI: 10.1002/pbc.31623 AbstractAbstract Not Available CategoryClass V. Pulmonary Hypertension Associated with Hematological, Systemic, Metabolic and Other DisordersMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Diseasec

Severe Precapillary Pulmonary Hypertension and Right Ventricular Failure After Hematopoietic Stem Cell Transplantation: Successful Outcomes With Aggressive Upfront Triple Therapy Read More »

Are Early, Frequent Echocardiograms Necessary to Improve Outcomes of Neonates with Congenital Diaphragmatic Hernia?

Michelle J. Yang, Ryan J. Carpenter, Katie W. Russell, Stephen J. Fenton, Christian C. Yost, Bradley A. YoderUniversity of Utah School of Medicine and Primary Children’s Hospital.United States Journal of PediatricsJ Pediatr 2025; DOI: 10.1016/j.jpeds.2025.114510 AbstractObjective: To determine if timing of first postnatal echocardiogram (ECHO), early vs delayed, affects the use of extracorporeal membrane oxygenation (ECMO) and

Are Early, Frequent Echocardiograms Necessary to Improve Outcomes of Neonates with Congenital Diaphragmatic Hernia? Read More »

Valsartan to Prevent Acquired Pulmonary Vein Stenosis in Pediatric Patients After Total Anomalous Pulmonary Venous Connection Surgery

Jin Shentu, Mingjie Zhang, Zhuoming Xu, Chen Wen, Hao Zhang, Zhongqun Zhu, Huiwen Chen, Guocheng ShiShanghai Children’s Medical Center and Shanghai Jiao Tong University. China Journal of the American Heart AssociationJ Am Heart Assoc 2025; 14: DOI: 10.1161/JAHA.124.036911 AbstractBackground: Recurrent pulmonary vein stenosis (PVS) following surgical repair of total anomalous pulmonary venous connection is associated with poor prognosis. Preclinical studies have shown that use of an angiotensin receptor blocker can attenuate intimal

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Inhaled Epoprostenol in Children With Pediatric Acute Respiratory Distress Syndrome: A Single-Center Retrospective Study

Eleanor J. Scalone, Alan G. Woodruff, Amit K. Saha, John M. Wright, Kristopher L. Dixon, Andora L. Bass, Michael J. Walsh, Michael C. McCroryWake Forest University School of Medicine. University of Pennsylvania Perelman School of Medicine.United States Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71010 AbstractBackground: Inhaled epoprostenol (iEpo) may improve oxygenation in adults with hypoxic respiratory failure,

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Case Report: severe pulmonary hypertension in a child with micronutrient deficiency

Laure Pache-Wannaz, Cristiana Voicu, Laurence Boillat, Nicole SekarskiLausanne University Hospital and University of Lausanne.Switzerland Frontiers in PediatricsFront Pediatr 2025; 13: DOI: 10.3389/fped.2025.1478889 AbstractWe describe the rare case of a previously healthy seven year-old boy, with an acute clinical onset of severe pulmonary hypertension. He recovered rapidly after vitamin supplementation. Patient history showed a highly selective food

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