Pediatric Pulmonary Vascular Disease

Risk Assessment and Monitoring of Chronic Pulmonary Hypertension in Premature Infants

Philip T. Levy, Amish Jain, Hythem Nawaytou, David Teitel, Roberta Keller, Jeffery Fineman, Robin Steinhorn, Steven H. Abman, Patrick J. McNamara, for the Pediatric Pulmonary Hypertension Network (PPHNet)Boston Children’s Hospital and Harvard Medical School. University of Toronto and Mount Sinai Hospital. University of California, San Francisco. Children’s National Health System. University of Colorado Anschutz Medical […]

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Evaluation and Management of Pulmonary Hypertension in Children with Bronchopulmonary Dysplasia

Usha Krishnan, Jeffrey A. Feinstein, Ian Adatia, Eric D. Austin, Mary P. Mullen, Rachel K. Hopper, Brian Hanna, Lew Romer, Roberta L. Keller, Jeffrey Fineman, Robin Steinhorn, John P. Kinsella, D. Dunbar Ivy, Erika Berman Rosenzweig, Usha Raj, Tilman Humpl, Steven H. Abman, for the Pediatric Pulmonary Hypertension Network (PPHNet)Columbia University Medical Center and Morgan

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Case report: Multisystemic smooth muscle dysfunction syndrome: a rare genetic cause of infantile interstitial lung disease

Qianying Li, Lidan Cui, Jun Su, Yuelin ShenChildren’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital and Zhengzhou Children’s Hospital. Beijing Children’s Hospital and Capital Medical University. China Frontiers in PharmacologyFront Pharmacol 2025; DOI: 10.3389/fphar.2024.1510969 AbstractMultisystemic smooth muscle dysfunction syndrome (MSMDS) is an autosomal dominant disorder caused by mutations in the ACTA2 gene, resulting in variable clinical manifestation

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Perioperative extra corporeal membrane oxygenation in neonates with transposition of the great arteries: 15 years of experience

Jesse A. Weeda, Roel L. F. van der Palen, Heleen E. Bunker-Wiersma, Lena Koers, Eelco van Es, Mark G. Hazekamp, Arjan B. te Pas, Peter Paul RoeleveldWillem-Alexander Children’s Hospital and Leiden University Medical Centre. Netherlands European Journal of Cardiothoracic SurgeryEur J Cardiothorac Surg 2025; DOI: 10.1093/ejcts/ezae442 AbstractBackground: Extracorporeal membrane oxygenation (ECMO) can act as a bridge to

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[Prognosis of bronchopulmonary dysplasia]

Ying-Zhen Zhou, Ting Wang, Xing-Meng Fu, Bing-Ming Peng, Zhou FuChildren’s Hospital of Chongqing Medical University and National Clinical Research Center for Child Health and Disorders.China Chinese Journal of Contemporary PediatricsZhongguo Dang Dai Er Ke Za Zhi 2025; 27: 115-120DOI: 10.7499/j.issn.1008-8830.2406004 AbstractChildren with bronchopulmonary dysplasia (BPD) often exhibit severe respiratory problems and significant pulmonary dysfunction during school

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Mortality Patterns in Pediatric Pulmonary Vein Stenosis: Insights Into Right Ventricular Systolic Pressure Associations

Daiji Takajo, Paul J. Critser, Michelle Cash, Melissa Magness, Russel HirschCincinnati Children’s Hospital Medical Center and University of Cincinnati.United States Journal of the American Heart AssociationJ Am Heart Assoc 2025; DOI: 10.1161/JAHA.124.037908DOI: 10.1161/JAHA.124.035037 (correction) AbstractBackground: Pulmonary vein stenosis in children is associated with a poor prognosis. However, the cause and risk factors for mortality remain uncertain.Methods: This retrospective, single-center

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Amniotic fluid stem cell extracellular vesicles as a novel fetal therapy for pulmonary hypoplasia: a review on mechanisms and translational potential

Fabian Doktor, Lina Antounians, Rebeca Lopes Figueira, Kasra Khalaj, Miriam Duci, Augusto ZaniHospital for Sick Children and University of Toronto. Leipzig University.Canada and Germany Stem Cells Translational MedicineStem Cells Transl Med 2025; 14: DOI: 10.1093/stcltm/szae095 AbstractDisruption of developmental processes affecting the fetal lung leads to pulmonary hypoplasia. Pulmonary hypoplasia results from several conditions including congenital diaphragmatic

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Postnatal management of preterm infants with congenital diaphragmatic hernia

Emma Williams, Stephanie Lau, Nimrah Abbasi, Eveline Lapidus-Krol, Priscilla P. L. Chiu, Brian T. KalishHospital for Sick Children and University of Toronto. Mount Sinai Hospital. Canada Pediatric Surgery InternationalPediatr Surg Int 2025; 41: DOI: 10.1007/s00383-025-05964-5 AbstractIntroduction: Congenital diaphragmatic hernia (CDH) in the preterm population is increasingly common in the current era of fetal endoluminal tracheal occlusion (FETO)

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Systemic Sirolimus Therapy Is Associated With Reduced Intervention Frequency in Pulmonary Vein Stenosis

Alyssa B. Kalustian, Joseph L. Hagan, Paige E. Brlecic, Ionela Iacobas, Rachel D. Vanderlaan, Joseph Burns, Thao T. Wu, Ravi Birla, Sharada Gowda, Manish Bansal, Srinath T. Gowda, Lindsay F. Eilers, Asra Khan, Juan Pablo Sandoval-Jones, Michiaki Imamura, Yishay Orr, Christopher A. Caldarone, Athar M. QureshiTexas Children’s Hospital and Baylor College of Medicine. Hospital for

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Safety and Efficacy of Selexipag for Pediatric Pulmonary Arterial Hypertension in Japanese Patients – An Open-Label Phase 2 Study

Toru Iwasa, Ryo Inuzuka, Hiroshi Ono, Yuichiro Sugitani, Hirokuni Yamazawa, Chihiro Hiraishi, Naoki Shiota, Shinichi Tanaka, Chieko Yamamoto, Ken-ichi Kurosaki, Masaru Miura, Satoshi YasukochiNational Cerebral and Cardiovascular Center. University of Tokyo. National Center for Child Health and Development. Japan Community Health Care Organization Kyushu Hospital. Hokkaido University. Nippon Shinyaku Company. Tokyo Metropolitan Children’s Medical Center.

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