Pediatric Pulmonary Vascular Disease

High-Altitude Pulmonary Edema in Mountain Community Residents

Christine Ebert-SantosEbert Family Santos.Columbia High Altitude Medicine and BiologyHigh Alt Med Biol 2017; 18: 278-284DOI: 10.1089/ham.2016.0100 AbstractHigh-altitude pulmonary edema (HAPE) affects lowlanders ascending quickly to elevations above 2440 m. Mountain resident children with no travel can sometimes develop HAPE as was observed over 30 years ago (Fasules et al., 1985). This is not well known and […]

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Reentry High Altitude Pulmonary Edema in the Himalayas

Satosh Baniya, Christopher Holden, Buddha BasnyatMountain Medicine Society of Nepal. Nepal International Clinic and Himalayan Rescue Association. Oxford University Clinical Research Unit. University of Oxford. Nepal and United Kingdom High Altitude Medicine and BiologyHigh Alt Med Biol 2017; 18: 425-427DOI: 10.1089/ham.2017.0088 AbstractReentry high altitude pulmonary edema (HAPE), a subset of HAPE, is a well recognized, life-threatening

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Safety of a novel portable inhaled nitric oxide generator for therapy of persistent pulmonary hypertension in neonates: a case series study

Yao Zhu, Jiongzhi He, Miner Cai, Lijun Wen, Minxu LiDongguan Maternal and Child Health Care Hospital. First Affiliated Hospital of Jinan University.China Translational PediatricsTransl Pediatr 2025; 14: 3305-3317DOI: 10.21037/tp-2025-535 AbstractBackground: Persistent pulmonary hypertension of the newborn (PPHN) is a life-threatening emergency in neonatal intensive care. Traditional treatments such as cylinder-based nitric oxide (NO) delivery systems rely on

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Fibrotic liver injury in biliary atresia: long-term implications

Maria Hukkinen, Mikko P PakarinenNew Children’s Hospital, University of Helsinki and Helsinki University Hospital.Finland World Journal of Pediatric SurgeryWorld J Pediatr Surg 2025; 8: DOI: 10.1136/wjps-2025-001098 AbstractNormalization of serum bilirubin after Kasai portoenterostomy (KPE) is a prerequisite for long-term native liver (NL) survival. Following a successful KPE, fibrotic liver injury progresses variably, although a significant proportion

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Clinical impact of treprostinil in neonates with persistent pulmonary hypertension refractory to inhaled nitric oxide: A retrospective cohort study

Tae Hyeong Kim, Song Ee Youn, Sung-Hoon ChungKyung Hee University College of Medicine and Kyung Hee University Hospital at Gangdong.Republic of Korea MedicineMedicine 2026; 105: DOI: 10.1097/MD.0000000000046984 AbstractPersistent pulmonary hypertension of the newborn (PPHN) has limited options when unresponsive to inhaled nitric oxide (iNO). We evaluated the role of intravenous treprostinil and whether early response classification

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High-altitude pulmonary edema in children

Ralph C. Frates Jr, Gunyon M. Harrison, George A. EdwardsBaylor Collegeof Medicine and the Texas Institute for Rehabilitation and Research.United States American Journal of Diseases of ChildrenAm J Dis Child 1977; 131: 687-689DOI: 10.1001/archpedi.1977.02120190081018 AbstractA 15-year-old boy with recurrent high-altitude pulmonary edema had previously been mistakenly treated for asthma and pneumonia. Clinical manifestations of this disorder,

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High-altitude pulmonary edema in the children and young adults of Leadville, Colorado

Charles H. Scoggin, Thomas M. Hyers, John T. Reeves, Robert F. GroverUniversity of Colorado Medical Center. United States New England Journal of MedicineN Engl J Med 1977; 297: 1269-1272DOI: 10.1056/NEJM197712082972309 AbstractAbstract Not Available CategoryHigh Altitude Pulmonary Edema Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication Article

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Pulmonary hypertension in pediatric patients with cystic fibrosis during acute pulmonary exacerbations: prevalence and associated factors

Zahra Roshanzamir, Fatemeh Mohammadi, Rohola ShirzadiNamazi Hospital and Shiraz University of Medical Sciences. Children’s Medical Center and Tehran University of Medical Sciences.Iran BioMedical Central Pulmonary MedicineBMC Pulm Med 2026; DOI: 10.1186/s12890-025-04095-w AbstractBackground: Cystic fibrosis (CF) is a multi-organ disorder in which respiratory complications account for the majority of its cause of mortality. This study aimed to investigate

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High-altitude pulmonary edema with absent right pulmonary artery

Billy Rios, David J. Driscoll, Dan G. McNamaraTexas Children’s Hospital and Baylor Cllege of Medicine.United States PediatricsPediatrics 1985; 75: 314-317DOI: https://doi.org/10.1542/peds.75.2.314 AbstractHigh-altitude pulmonary edema potentially is fatal. Adults with unilateral absence of a right pulmonary artery are particularly susceptible to high-altitude pulmonary edema. The occurrence of high-altitude pulmonary edema was documented in a child with

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Physical adaptation of children to life at high altitude

K. De Meer, H. S. A. Heymans, W. G. ZijlstraUniversity Children’s Hospital Het Wilhelmina Kinderziekenhuis. Beatrix Children’s Clinic and University Hospital Groningen.Netherlands European Journal of PediatricsEur J Pediatr 1995; 154: 263–272DOI: Not Availanble AbstractChildren permanently exposed to hypoxia at altitudes of > 3000 m above sea level show a phenotypical form of adaptation. Under these

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