Pediatric Pulmonary Vascular Disease

Milrinone Versus Sildenafil in Treatment of Neonatal Persistent Pulmonary Hypertension: A Randomized Control Trial

Safaa S. Iman, Rania A. El-Farrash, Amr S. Taha, Ghada A. SalehAin Shams University and Cairo Ministry of Health.Egypt Journal of Cardiovascular PharmacologyJ Cardiovasc Pharmacol 2022; 80: 746-752DOI: 10.1097/FJC.0000000000001332 AbstractPersistent pulmonary hypertension of the newborn (PPHN) is a condition caused by failure of pulmonary vascular adaptation at birth, resulting in severe hypoxia. Several therapeutic modalities are […]

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A case of acquired von Willebrand disease in severe pediatric pulmonary hypertension contributing to bleeding following reverse Potts shunt

Rachel T. Sullivan, Clara Lo, Elisabeth Martin, Rebecca J. Kameny, Rachel K. HopperStanford University School of Medicine and Lucile Packard Children’s Hospital.United States Pulmonary CirculationPulm Circ 2022; 12: DOI: 10.1002/pul2.12042 AbstractThe reverse Potts shunt is increasingly used as a palliative measure for end-stage pulmonary arterial hypertension (PAH) as a means to offload the right ventricle and

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Factors associated with discontinuation of pulmonary vasodilator therapy in children with bronchopulmonary dysplasia-associated pulmonary hypertension

Catherine M. Avitabile, Xuemei Zhang, Steve B. Ampah, Yan Wang, Devon Ash, Kathleen Nilan, Laura Mercer-Rosa, Julie L. Fierro, David B. Frank, Kathleen A. GibbsUniversity of Pennsylvania and Children’s Hospital of Philadelphia.United States Journal of PerinatologyJ Perinatol 2022; 42: 1246-1254DOI: 10.1038/s41372-022-01421-6 AbstractObjective: To evaluate factors associated with discontinuation of pulmonary vasodilator therapy in bronchopulmonary dysplasia-related pulmonary hypertension

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Late onset of pulmonary hypertension in very low birth weight infants

Joseph Ginski, Dmitry Tumin, Devon Kuehn, Jason Higginson, Scott MacGilvrayEast Carolina UniversityUnited States Journal of Maternal Fetal and Neonatal MedicineJ Matern Fetal Neonatal Med 2022; 35: 3516-3518DOI: 10.1080/14767058.2020.1826924 AbstractIntroduction: Pulmonary hypertension (PH) is a recognized complication of bronchopulmonary dysplasia (BPD). Recent guidelines recommend evaluating all infants with BPD for PH via echocardiogram, but the specific timing of this screening

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Predicting treatment of pulmonary hypertension at discharge in infants with congenital diaphragmatic hernia

Burhan Mahmood, Karna Murthy, Natalie Rintoul, Mark Weems, Sarah Keene, Beverly Brozanski, Robert DiGeronimo, Beth Haberman, Holly Hedrick, Jason Gien, Ruth Seabrook, Noorjahan Ali, Rachel Chapman, John Daniel, Allen Harrison, Yvette Johnson, Nicolas F. M. Porta, Michael Uhing, Isabella Zaniletti, Theresa R. GroverChildren’s Hospitals Neonatal ConsortiumUnited States Journal of PerinatologyJ Perinatol 2022; 42: 45-52DOI: 10.1038/s41372-021-01249-6 AbstractObjective: To

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The Clinical and Cost Utility of Cardiac Catheterizations in Infants with Bronchopulmonary Dysplasia

Emily L. Yang, Philip T. Levy, Paul J. Critser, Dmitry Dukhovny, Patrick D. EversOregon Health and Sciences University. Harvard Medical School and Boston Children’s Hospital. Cincinnati Children’s Hospital Medical Center, Cincinnati, OH; Department of Pediatrics, University of Cincinnati College of Medicine and Cincinnati Children’s Hospital Medical Center.United States Journal of PediatricsJ Pediatr 2022; 246: 56-63DOI: 10.1016/j.jpeds.2022.04.009

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SCMR expert consensus statement for cardiovascular magnetic resonance of acquired and non-structural pediatric heart disease

Adam L. Dorfman, Tal Geva, Margaret M. Samyn, Gerald Greil, Rajesh Krishnamurthy, Daniel Messroghli, Pierluigi Festa, Aurelio Secinaro, Brian Soriano, Andrew Taylor, Michael D. Taylor, René M. Botnar, Wyman W. LaiUniversity of Michigan and C.S. Mott Children’s Hospital.Boston Children’s Hospital. Medical College of Wisconsin. University of Texas Southwestern Medical Center. Nationwide Children’s Hospital. Deutsches Herzzentrum

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Repolarization Dispersion Is Associated With Diastolic Electromechanical Discoordination in Children With Pulmonary Arterial Hypertension

Michal Schäfer, Benjamin S. Frank, D. Dunbar Ivy, Max B. Mitchell, Kathryn K. Collins, Pei-Ni Jone, Johannes C. von AlvenslebenUniversity of Colorado and Children’s Hospital Colorado.United States Journal of the American Heart AssociationJ Am Heart Assoc 2022; 11: DOI: 10.1161/JAHA.121.024787 AbstractBackground: Electromechanical dyssynchrony is a well described comorbidity in pulmonary arterial hypertension (PAH). ECG-derived measurements reflective

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Serotonin-deficient neonatal mice are not protected against the development of experimental bronchopulmonary dysplasia or pulmonary hypertension

Danielle S. Roberts, Laura G. Sherlock, Janelle N. Posey, Jamie L. Archambault, Eva S. Nozik, Cassidy A. DelaneyUniversity of Colorado Anschutz Medical Campus.United States Physiological ReportsPhysiol Rep 2022; 10: DOI: 10.14814/phy2.15482 AbstractSerotonin (5-hydroxytryptamine, 5-HT) is a potent pulmonary vasoconstrictor and contributes to high pulmonary vascular resistance in the developing ovine lung. In experimental pulmonary hypertension (PH), pulmonary expression of tryptophan hydroxylase-1 (TPH1),

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Association between pulmonary vein stenosis and necrotizing enterocolitis or gastrointestinal pathology: A case-control study

Jennifer Duchon, Christiana Farkouh‑Karoleski, Dominique D. Bailey, Usha S. KrishnanBronx Care Hospital System. Columbia University Irving Medical Center. Valley Health System. United States Annals of Pediatric CardiologyAnn Pediatr Cardiol 2022; 15: 13-19DOI: 10.4103/apc.apc_210_21 AbstractObjective: Pulmonary vein stenosis (PVS) is an emerging cause of pulmonary hypertension in preterm infants. It is an often lethal condition with poor long.term

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