Pediatric Pulmonary Vascular Disease

Treatment and outcomes of chylothorax in children: 20-year experience of a single institute

Kanokpan Ruangnapa, Wanaporn Anuntaseree, Kantara Saelim, Pharsai Prasertsan, Maneerat Puwanant, Supaporn DissanevatePrince of Songkla UniversityThailand Journal of Thoracic DiseaseJ Thorac Dis 2022; 14: 3719-3726DOI: 10.21037/jtd-22-474 AbstractBackground: Chylothorax is an uncommon cause of pleural effusion in children. This study aimed to determine the characteristics, treatment strategies, and outcomes of chylothorax in children from a single institute.Methods: The 65 episodes […]

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Congenital Chylothorax of the Newborn: A Systematic Analysis of Published Cases between 1990 and 2018

Bernhard Resch, Gülsen Sever Yildiz, Friedrich ReitererMedical University of GrazAustria RespirationRespiration 2022; 101: 84-96DOI: 10.1159/000518217 AbstractBackground: Congenital chylothorax (CCT) of the newborn is a rare entity but the most common cause of pleural effusion in this age-group. We aimed to find the optimal treatment strategy.Material and methods: A PubMed search was performed according to the PRISMA criteria. All

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Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia

Viktor Lukacs, Jayanti Mathur, Rong Mao, Pinar Bayrak-Toydemir, Melinda Procter, Stuart M. Cahalan, Helen J. Kim, Michael Bandell, Nicola Longo, Ronald W. Day, David A. Stevenson, Ardem Patapoutian, Bryan L. KrockThe Scripps Research Institute. Genomics Institute of the Novartis Research Foundation. ARUP Institute for Clinical and Experimental Pathology. University of Utah. Stanford University. Children’s Hospital

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Intranodal cone-beam computed tomographic lymphangiography with water-soluble iodinated contrast agent for evaluating chylothorax in infants – preliminary experience at a single institution

Dicken Wong, Kin Fen Kevin Fung, Hay-Son Robin Chen, Kin Sing Lun, Yee Ling Elaine KanKwong Wah Hospital. Hong Kong Children’s Hospital. Hong Kong Pediatric RadiologyPediatr Radiol 2023; 53: 179-183DOI: 10.1007/s00247-022-05441-4 AbstractThis brief report demonstrates the diagnostic utility of cone-beam CT lymphangiography (CBCTL) with intranodal injection of water-soluble iodinated contrast agent for assessing lymphatic disorders in

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Investigation into the genetics of fetal congenital lymphatic anomalies

Daniella Rogerson, Anna Alkelai, Jessica Giordano, Madhulatha Pantrangi, Meng-Chang Hsiao, Chia-Ling Nhan-Chang, Joshua E. Motelow, Vimla Aggarwal, David Goldstein, Ron Wapner, Carrie J. ShawberColumbia University Vagelos College of Physicians and Surgeons. Columbia University Irving Medical Center.United States Prenatal DiagnosisPrenat Diagn 2023; DOI: 10.1002/pd.6345 AbstractObjective: Congenital lymphatic anomalies (LAs) arise due to defects in lymphatic development and often

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Evaluation of Clinical Findings in Children with Chylothorax: A Descriptive Study

Halime Nayir Büyükşahin, Nagehan Emiralioğlu, H. Nursun Özcan, Birce Sunman, İsmail Güzelkaş, Didem Alboğa, Meltem Akgül Erdal, Tezer Kutluk, Nilgün Kurucu, Ebru Yalçın, Deniz Doğru, Ugur Özçelik, Nural KiperHacettepe University School of Medicine and Ihsan Dogramaci Children’s Hospital. Hacettepe University Cancer Institute.Turkey Turkish Archives of PediatricsTurk Arch Pediatr 2023; 58: 28-33DOI: 10.5152/TurkArchPediatr.2022.22182 AbstractObjective: Chylothorax refers to the

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Propranolol Therapy for Congenital Chylothorax

Roxane Handel-Orefice, Bevin Midura, June K. Wu, Elvira Parravicini, Russell S. Miller, Carrie J. ShawberColumbia University Vagelos College of Physicians and Surgeons and New York-Presbyterian Morgan Stanley Children’s HospitalUnited States PediatricsPediatrics 2023; 151: DOI: 10.1542/peds.2022-058555 AbstractCongenital chylothorax is a rare and often severe anomaly without well-established medical therapies. Previously, propranolol use in patients with lymphatic malformations

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Diagnosis and treatment of diffuse pulmonary lymphangioma in children: A case report

Xiaopu Sun, Chengyu Lu, Zhanhang Huang, Jiaxing Xu, Huiyi Zhu, Sen Yang, Deihui ChenThe First Affiliated Hospital of Guangzhou Medical University.China Experimental and Therapeutic MedicineExp Ther Med 2023; 25: DOI: 10.3892/etm.2023.11874 AbstractThe present study aimed to investigate the clinical characteristics of diffuse pulmonary lymphangioma (DPL) in children to improve the diagnosis and treatment of this disease.

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Hyperoxia Disrupts Lung Lymphatic Homeostasis in Neonatal Mice

Nithyapriya Shankar, Shyam Thapa, Amrit Kumar Shrestha, Poonam Sarkar, M. Waleed Gaber, Roberto Barrios, Binoy ShivannaTexas Children’s Hospital and Baylor College of Medicine. Houston Methodist Hospital.United States AntioxidantsAntioxidants 2023; DOI: 10.3390/antiox12030620 AbstractInflammation causes bronchopulmonary dysplasia (BPD), a common lung disease of preterm infants. One reason this disease lacks specific therapies is the paucity of information on

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Dynamic Contrast-Enhanced Magnetic Resonance Lymphangiography and Lymphatic Interventions for Pediatric Patients with Various Lymphatic Diseases

Yura Ahn, Hyun Jung Koo, Hee Mang Yoon, Jooae Choe, Eun-Young Joo, Myung-Hee Song, Dong Hyun Yang, Joon-Won Kang, Ji Hoon ShinAsan Medical Center and University of Ulsan College of Medicine.Republic of Korea Lymphatic Research and BiologyLymphat Res Biol 2023; 21: 141-151DOI: 10.1089/lrb.2021.0106 AbstractBackground: To demonstrate the magnetic resonance lymphangiography (MRL) imaging findings of lymphatic diseases and

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