Pediatric Pulmonary Vascular Disease

Single-cell transcriptomic profiling of microvascular endothelial cell heterogeneity in congenital diaphragmatic hernia

Jason O. Robertson, Peter Bazeley, Serpil C. Erzurum, Kewal AsosinghCleveland Clinic.United States Scientific ReportsSci Rep 2023; 13DOI: 10.1038/s41598-023-37050-y AbstractCongenital diaphragmatic hernia (CDH) is a neonatal anomaly that includes pulmonary hypoplasia and hypertension. We hypothesized that microvascular endothelial cell (EC) heterogeneity is different in CDH lungs and related to lung underdevelopment and remodeling. To test this, we […]

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Evaluation of Postnatal Complications in Clinical and Histological Chorioamnionitis in Extremely Preterm Infants: A Japanese Cohort Study

Shuji Ishida, Hidehiko Nakanishi, Rika Sekiya, Kohei Kawada, Yukako Kosaka, Ayano Yamaguchi, Mari Ooka, On befalf of the Neonatal Research Network of JapanKitasato University.Japan American Journal of PerinatologyAm J Perinatol 2023; DOI: 10.1055/a-2113-4332 AbstractObjective: Terminating pregnancy appropriately before the intrauterine infection has progressed may have an improved prognosis for preterm infants. We evaluate how the combination of histological chorioamnionitis (hCAM) and clinical chorioamnionitis

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Dynamics of pulmonary hypertension severity in the first 48 h in neonates with prenatally diagnosed congenital diaphragmatic hernia

Judith Leyens, Lukas Schroeder, Annegret Geipel, Christoph Berg, Bartolomeo Bo, Lotte Lemloh, Neil Patel, Andreas Mueller, Florian KipfmuellerChildren’s Hospital, University of Bonn.  Royal Hospital for Children.Germany and United Kingdom Frontiers in PediatricsFront Pediatr 2023; 11DOI: 10.3389/fped.2023.1164473 AbstractIntroduction: Pulmonary hypertension (PH) is one of the major contributing factors to the high morbidity and mortality in neonates with congenital

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Molecular insights using spatial transcriptomics of the distal lung in Congenital Diaphragmatic Hernia

Krithika Lingappan, Oluyinka O. Olutoye II, Abiud Cantu, Manuel Eliezer Cantu Gutierrez, Nahir Cortes-Santiago, J. D. Hammond, Jamie Gilley, Joselyn Rojas Quintero, Hui Li, Francesca Polverino, Jason P. Gleghorn, Sundeep G. KeswaniChildren’s Hospital of Philadelphia. Baylor College of Medicine and Texas Children’s Hospital. University of Delaware. United States American Journal of Physiology Lung Cellular and

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Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition

Maja Hanuna, Joseph Pattathu, Joscha Buech, Christine Kamla, Nikolaus Kneidinger, Juergen Behr, Katrin Milger, Tobias Veit, Marina Nagel, Jan Abicht, Robert Dalla-Pozza, Marcus Fischer, Andre Jakob, Matthias Hermann, Rene Schramm, Laura L. Rosenthal, Nikolaus Haas, Jürgen Hörer, Christian Hagl, Sebastian G. MichelLudwig Maximilian University Munich. Munich Heart Alliance. Comprehensive Pneumology Center Munich. Heart and Diabetes

Case report: Central venous catheter thrombosis complicated by chronic thromboembolic disease/pulmonary hypertension in two children requiring parenteral nutrition Read More »

Pulmonary hypertension among preterm infants born at 22 through 32 weeks gestation in France: Prevalence, survival, morbidity and management in the EPIPAGE-2 cohort study

Sophie Breinig, Virginie Ehlinger, Jean-Christophe Roze, Laurent Storme, Heloise Torchin, Xavier Durrmeyer, Gilles Cambonie, Christophe Delacourt, Pierre-Henri Jarreau, Lionel Berthomieu, Olivier Brissaud, Valerie Benhammou, Geraldine Gascoinb, Catherine Arnaud, Pierre-Yves AnceljChildren’s Hospital and Toulouse University. Nantes University Hospital. Lille University Hospital. Assistance Publique-Hôpitaux de Paris. CHI Créteil. Montpellier University Hospital. Necker Children’s Hospital. Bordeaux University Hospital.

Pulmonary hypertension among preterm infants born at 22 through 32 weeks gestation in France: Prevalence, survival, morbidity and management in the EPIPAGE-2 cohort study Read More »

Intravenous prostacyclins for right ventricular failure following left ventricular assist device in paediatric heart failure

Laura J. Radel, Mehreen Iqbal, Megan GriffithsUniversity of Texas Southwestern.United States Cardiology in the YoungCardiol Young 2023; DOI: 10.1017/S1047951123001725 AbstractRight ventricular failure after placement of left ventricular assist device in paediatric heart failure is associated with increased mortality. We report successful use of intravenous prostacyclin for right ventricular support and pulmonary hypertension after initiation of left

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Two-stage learning-based prediction of bronchopulmonary dysplasia in very low birth weight infants: a nationwide cohort study

Jae Kyoon Hwang, Dae Hyun Kim, Jae Yoon Na, Joonhyuk Son, Yoon Ju Oh, Donggoo Jung, Chang-Ryul Kim, Tae Hyun Kim, Hyun-Kyung ParkHanyang University College of Medicine and Hanyang University.Republic of Korea Frontiers in PediatricsFront Pediat 2023; 11DOI: 10.3389/fped.2023.1155921 AbstractIntroduction: The aim of this study is to develop an enhanced machine learning-based prediction models for bronchopulmonary dysplasia

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Neurodevelopmental Outcomes of Preterm Infants Born <29 Weeks with Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension: A Multicenter Study

Soumya R. Thomas, Sunil K. Jain, Prashanth Murthy, Chacko J. Joseph, Amuchou Soraisham, Selphee Tang, Aliyah Dosani, Abhay LodhaUniversity of Calgary and Alberta Children’s Hospital. University of Texas Medical Branch. Mount Royal University.Canada and United States American Journal of PerinatologyAm J Perinatol 2023; DOI: 10.1055/a-2121-8878 AbstractObjective: This study aimed to determine neurodevelopmental outcomes of preterm infants born

Neurodevelopmental Outcomes of Preterm Infants Born <29 Weeks with Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension: A Multicenter Study Read More »

Vein of Galen aneurysmal malformation in newborns: a retrospective study to describe a paradigm of treatment and identify risk factors of adverse outcome in a referral center

Silvia Buratti, Marisa Mallamaci, Giulia Tuo, Mariasavina Severino, Domenico Tortora, Costanza Parodi, Andrea Rossi, Francesco Pasetti, Lucio Castellan, Valeria Capra, Ferruccio Romano, Patrizia De Marco, Marco Pavanello, Gianluca Piatelli, Dario Paladini, Maria Grazia Calevo, Andrea Moscatelli, on behalf of the IGG VGAM TeamIRCCS Istituto Giannina Gaslini and University of Genoa. San Martino Polyclinic Hospital. Italy

Vein of Galen aneurysmal malformation in newborns: a retrospective study to describe a paradigm of treatment and identify risk factors of adverse outcome in a referral center Read More »

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