Pediatric Pulmonary Vascular Disease

Lung transplantation with concomitant cardiac repair for congenital hypoplasia of bilateral pulmonary arteries and patent ductus arteriosus

Che‑Chih Cheng, Ming‑Tai Lin, Shu‑Chien Huang, Hsao‑Hsun HsuKaohsiung Armed Forces General Hospital. National Taiwan University Hospital and National Taiwan University College of Medicine.Taiwan Journal of Cardiothoracic SurgeryJ Cardiothorac Surg 2022; 17: DOI: 10.1186/s13019-022-01792-z AbstractBackground: Profound pulmonary arterial hypertension with end-stage right heart failure is considered to be the main cause of death in children with un-repaired congenital […]

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Innovative Fetal Therapy for a Giant Congenital Pulmonary Airway Malformation with Hydrops

Denise B. Klinkner, Thomas Atwell, Ayssa Teles Abrao Trad, Matthew R. Callstrom, Mohamed Yasir Qureshi, Ellen Bendel Stenzel, Mauro Schenone, Rodrigo RuanoMayo Clinic. University of Miami.United States Fetal Diagnosis and TherapyFetal Diagn Ther 2022; 49: 250-255DOI: 10.1159/000521690 AbstractIntroduction: Congenital pulmonary airway malformations (CPAMs) complicated by hydrops portend significant morbidity and mortality, with fetal survival estimates less than

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Pilot study for comparative assessment of dual-energy computed tomography and single-photon emission computed tomography V/Q scanning for lung perfusion evaluation in infants

Karen I. Ramirez-Suarez, Christian A. Barrera, Hansel J. Otero, David M. Biko, Lisa J. States, Sabah Servaes, Xiaowei Zhu, James C. Davis, Josrph Piccione, Jordan B. RappChildren’s Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine. West Virginia University Medicine Children’s Hospital.United States Pediatric PulmonologyPediatr Pulmonol 2022; 57: 702-710DOI: 10.1002/ppul.25788 AbstractObjective: To evaluate clinical applications

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Severe Congenital Syphilis in the Neonatal Intensive Care Unit: A Retrospective Case Series

Samia Aleem, LaShawndra Walker, Chi D. Hornik, Michael J. Smith, Chad A. Grotegut, Kristin E. D. WeimerDuke University. Wake Forest Baptist Health.United States Pediatric Infectious Disease JournalPediatr Infect Dis J 2022; 41: 335-339DOI: 10.1097/INF.0000000000003370 AbstractBackground: There has been a 291% relative increase in congenital syphilis (CS) cases in the United States from 2015 to 2019. Although the

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Prominent renal complications associated with MMACHC pathogenic variant c.80A > G in Chinese children with cobalamin C deficiency

Xiaoyu Liu, Huijie Xiao, Yong Yao, Suxia Wang, Hongwen Zhang, Xuhui Zhong, Yanling Yang, Jie Ding, Fang WangPeking University First Hospital.China Frontiers in PediatricsFront Pediatr 2023; DOI: 10.3389/fped.2022.1057594 AbstractObjective: CblC deficiency, the most common cobalamin metabolic abnormality, is caused by pathogenic variants in the MMACHC gene. The renal complications of this disease have been described only in a small

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The Association of Passive Smoking and Serum Urotensin-II Levels in Children

Hayrunnisa Bekis Bozkurt, Muhammed Yayla, Damla Binnetoglu, Multehan EvranKafkas University. Harran District Health of Directorate.Turkey Annals da Academia Brasileira de CienciasAn Acad Bras Cienc 2022; 94: DOI: 10.1590/0001-3765202220201488 AbstractUrotensin-II (UT-II) is the most powerful vasoconstrictor agent and is known to play a role in heart failure, diabetes, pulmonary hypertension and asthma. The effect of passive smoking

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Growth and differentiation factor 15 (GDF15) levels predict adverse respiratory outcomes in premature neonates

Faeq Almudares, Joseph Hagan, Xinpu Chen, Sridevi Devaraj, Bhagavatula Moorthy, Krithika LingappanBaylor College of Medicine. Children’s Hospital of Philadelphia.United States Pediatric PulmonologyPediatr Pulmonol 2023; 58: 271-278DOI: 10.1002/ppul.26197 AbstractGrowth and differentiation factor 15 (GDF15) is a stress-responsive cytokine, and its expression increases during inflammation, hyperoxia, and senescence. Significantly, GDF15 is secreted by the placenta, and maternal levels

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Improved Outcomes of Infant Lung Transplantation Over 3 Decades

Horacio G. Carvajal, Taylor C. Merritt, Matthew W. Canter, Aaron M. Abarbanell, Dilip S. Nath, Pirooz EghtesadyWashington University School of Medicine and St. Louis Children’s Hospital. University of Texas Health San Antonio.United States Annals or Thoracic SurgeryAnn Thorac Surg 2022; 114: 184-192DOI: 10.1016/j.athoracsur.2021.04.032 AbstractBackground: Lung transplantation is the definitive surgical treatment for end-stage lung disease. However, infants

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Total Anomalous Pulmonary Venous Connection Repair: Single-Center Outcomes in a Lower-Middle Income Region

Praveen Reddy Bayya, Shruti Varghese, Jessin Puliparambil Jayashankar, Abish Sudhakar, Rakhi Balachandran, Brijesh Parayaru Kottayil, Balaji Srimurugan, Praveen Kerala Varma, Praveen Kumar Neema, R. Krishna KumarAmrita Institute of Medical Sciences and Research CentreIndia World Journal for Pediatric and Congenital Heart SurgeryWorld J Pediatr Congenit Heart Surg 2022; 13: 458-465DOI: 10.1177/21501351221103492 AbstractBackground: The management of total anomalous pulmonary

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Safety of chronic high-dose calcium channel blockers exposure in children with pulmonary arterial hypertension

Yan Wu, Fu-Hua Peng, Xin Gao, Xin-Xin Yan, FengWen Zhang, Jiang-Shan Tan, Song Hu, Lu HuaFuwai Hospital and Chinese Academy of Medical Sciences and Peking Union Medical College.China Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2022; DOI: 10.3389/fcvm.2022.918735 AbstractBackground: Chronic calcium channel blockers (CCBs) are indicated in children with idiopathic/heritable pulmonary arterial hypertension (IPAH/HPAH) and positive response to

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