Pediatric Pulmonary Vascular Disease

Use of Metformin in Pulmonary Vein Stenosis after TAPVR Repair

Edward C. Kirkpatrick, Michael E. Mitchell, MD, William G. Thilly, Joseph Cava, Aoy Tomita-Mitchell, Elena V. GostjevaChildren’s Hospital of Wisconsin and Medical College of Wisconsin. Massachusetts Institute of Technology. United States Global Pediatric HealthGlob Pediatr Health 2020;DOI: 10.1177/2333794X20958924 AbstractAbstract Not Available CategoryClass II. Pulmonary Hypertension Associated with Pulmonary Vein StenosisMedical Therapy. Efficacy or Lack of EfficacyMedical Therapy. Adverse Effects or Lack of Adverse Effects Age Focus: Pediatric Pulmonary […]

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Maternal treatment with selective serotonin reuptake inhibitors during pregnancy and delayed neonatal adaptation: a population-based cohort study

Marie-Coralie Cornet, Yvonne W. Wu, Heather Forquer, Lyndsay A. Avalos, Achyuth Sriram, Aaron W. Scheffler, Thomas B. Newman, Michael W. KuzniewiczUniversity of California San Francisco. Kaiser Permanente Northern California.United States Archives of Disease in Children Fetal and Neonatal EditionArch Dis Child Fetal Neonatal Ed 2023; DOI: 10.1136/archdischild-2023-326049 AbstractObjective: Selective serotonin reuptake inhibitor (SSRI) use is common in

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Bilateral disease and early age at presentation are associated with shorter survival in patients with congenital heart disease and intraluminal pulmonary vein stenosis

Sowmya Balasubramanian, Maliha Rehman, Kimberlee Gauvreau, Kathy J. JenkinsChildren’s Hospital Boston.United States Congenital Heart DiseaseCongenit Heart Dis 2012; 7: 378-386DOI: 10.1111/j.1747-0803.2012.00647.x AbstractPurpose: Pulmonary vein stenosis (PVS) is a progressive disease that is frequently lethal. We have previously identified neoproliferation of myofibroblasts as the mechanism for progressive intraluminal PVS. PVS occurs in association with other congenital heart diseases

Bilateral disease and early age at presentation are associated with shorter survival in patients with congenital heart disease and intraluminal pulmonary vein stenosis Read More »

A prospective phase II trial of vinblastine and methotrexate in multivessel intraluminal pulmonary vein stenosis in infants and children

Maliha Rehman, Kathy J. Jenkins, Amy L. Juraszek, Jean A. Connor, Kimberlee Gauvreau, Muhammad Muneeb, Laureen M. Sena, Steven D. Colan, Terry Saia, Mark W. KieranChildren’s Hospital, Boston.United States Congenital Heart DiseaseCongenit Heart Dis 2011; 6: 608-623DOI: 10.1111/j.1747-0803.2011.00574.x AbstractObjective: To determine the safety and efficacy of the chemotherapeutic agents vinblastine and methotrexate in the treatment of children

A prospective phase II trial of vinblastine and methotrexate in multivessel intraluminal pulmonary vein stenosis in infants and children Read More »

Vascular reactivity is altered in the placentas of fetuses with congenital diaphragmatic hernia

Emily J. J. Horn-Oudshoorna, Michelle Broekhuizena, Madhavi S. Harhangi, Sinno H. P. Simons, Alex J. Eggink, A. H. Jan Danser, Irwin K. M. Reiss, Philip L. J. DeKoninckErasmus MC University Medical Center.Netherlands PlacentaPlacenta 2023; 145: 51-59DOI: 10.1016/j.placenta.2023.11.015 AbstractIntroduction: Infants with congenital diaphragmatic hernia (CDH) often develop pulmonary hypertension but frequently fail to respond to vasodilator therapy, for

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Intraluminal Pulmonary Vein Stenosis in Children: A “New” Lesion

Viviane G. Nasr, Ryan Callahan, Zachary Wichner, Kirsten C. Odegard, James A. DiNardoBoston Children’s Hospital.United States Anesthesia and AnalgesiaAnesth Analges 2019; 129: 27-40DOI: 10.1213/ANE.0000000000003924 AbstractPulmonary vein stenosis (PVS) is a rare disorder that leads to progressive narrowing of the extrapulmonary veins. PVS has been reported in both children and adults and in its worse iteration leads

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Pulmonary vein stenosis: Case report and literature review

Reshma Amin, S. Kwon, Y. Moayedi, Neil SweezeyHospital for Sick Children.Canada Canadian Respiratory JournalCan Respir J 2009; 16: e77-e80DOI: 10.1155/2009/791653 AbstractBackground: Pulmonary vein stenosis is a rare cause of pulmonary hypertension, with variable onset and presentation. One or more of the four pulmonary veins can be primarily or secondarily affected. A five-month-old girl presented with respiratory distress,

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Simvastatin restores pulmonary endothelial function in the setting of pulmonary over-circulation

Jason T. Boehme, Xutong Sun, Qing Lu, Jubilee Barton, Xiaomin Wu, Wenhui Gong, Gary W. Raff, Sanjeev A. Datar, Ting Wang, Jeffrey R. Fineman, Stephen M. BlackUniversity of California San Francisco. Howard Wertheim College of Medicine and Florida International University. University of Arizona Health Sciences. University of California Davis. United States Nitric OxideNitric Oxide 2023;

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Low-dose diazoxide is safe and effective in infants with transient hyperinsulinism

Neha Malhotra, Daphne Yau, Annaruby Cunjamalay, Buddhi Gunasekara, Athanasakopoulou S., Clare Gilbert, Kate Morgan, Mehul Dattani, Antonia DastamaniGreat Ormond Street Hospital for Children. University of Saskatchewan. Medical School of Queen Mary University.United Kingdom and Canada Clinical EndocrinologyClin Endocrinol 2023; DOI: 10.1111/cen.14987 AbstractObjective: Transient hyperinsulinism (THI) is the most common form of recurrent hypoglycaemia in neonates beyond the

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Long-term outcomes and immune profiling in children with multisystem inflammatory syndrome (MIS-C)

Indira Jaxybayeva, Riza Boranbayeva, Minira Bulegenova, Natalya Urazalieva, Valentin Gerein, Lyazat ManzhuovaAsfendiyarov Kazakh National Medical University. Goethe University Hospital.Kazakhstan and Germany Acta BiomedicaActa Biomed 2023;DOI: 10.23750/abm.v94i6.14788 AbstractBackground and aim: Existing follow-up data after MIS-C is limited.Purpose of the study: to investigate the long-term consequences in children who have undergone MIS-C.Methods: The retrospective study included 93 children. The identified changes

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