Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease

Effects of sildenafil and metformin on endothelin-1 in the progression of pulmonary hypertension

Agus Cahyono, Irwanto, Mahrus Abdur Rahman, Widjiati WidjiatiUniversitas Airlangga. Universitas Surabaya. Indonesia Open Veterinary JournalOpen Vet J 2025; 15: 3087-3096DOI: 10.5455/OVJ.2025.v15.i7.20 AbstractBackground: Pulmonary hypertension (PH) is a progressive and potentially fatal condition if left untreated. Currently, only sildenafil and bosentan have been approved by the Food and Drug Administration for the medical treatment of pediatric patients. The […]

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Technical Challenges in Studying Infectious Disease-Associated Pulmonary Hypertension in Low- and Middle-Income Countries with Limited Resources

Jennifer van Heerden, Irina Mbanze, Elizabeth Louw, Olukayode Aremu, Anastase Dzudie, Ana Mocumbi, Threnesan Naidoo, Brian Allwood, Friedrich ThienemannUniversity of Oxford. Maputo Central Hospital. University of Cape Town. University of Stellenbosch. Douala General Hospital. Universidade Eduardo Mondlane. Walter Sisulu University. University of Zurich.United Kingdom, Mozambique, South Africa, Cameroon and Switzerland Infectious Disease ReportsInfect Dis Rep

Technical Challenges in Studying Infectious Disease-Associated Pulmonary Hypertension in Low- and Middle-Income Countries with Limited Resources Read More »

Global, Regional, and National Burden of Pulmonary Arterial Hypertension from 1990 to 2021 and Projections to 2040: A Systematic Analysis of Incidence, Mortality, and Disability-Adjusted Life Years

Lin-Ling Yu, Ding-Sheng Jiang, Xiong Wang, Ze-Min Fang, Wei-Hong Chen, JinZhu Zhao, Xin Yi, Wei LuTongji Hospital, Tongji Medical College and Huazhong University of Science and Technology. Chinese Academy of Medical Sciences. Renmin Hospital of Wuhan University. China Current Medical ScienceCurr Med Sci 2025; DOI: 10.1007/s11596-025-00108-1 AbstractObjective: Pulmonary arterial hypertension (PAH) poses a growing global health challenge,

Global, Regional, and National Burden of Pulmonary Arterial Hypertension from 1990 to 2021 and Projections to 2040: A Systematic Analysis of Incidence, Mortality, and Disability-Adjusted Life Years Read More »

Efficacy and Safety of Pulmonary Vasodilator and Inodilator Drugs in Congenital Heart Disease Surgery: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

Martina Ollosu, Vincenzo Francesco Tripodiy, Carlotta Aresu, Giammarco Ledda, Francesca Manai, Chiara Marini, Mario Musu, Mariachiara Ippolitoz, Andrea Cortegianiz, Gabriele Finco, Salvatore SardoUniversity of Cagliari. “Gaetano Martino” University Hospital. University Hospital Policlinico Paolo Giaccone. Italy Journal of Cardiothoracic and Vascular AnesthesiaJ Cardiothorac Vasc Anesth 2025; DOI: 10.1053/j.jvca.2025.08.053 AbstractBackground: Perioperative management of congenital heart disease (CHD) surgery presents

Efficacy and Safety of Pulmonary Vasodilator and Inodilator Drugs in Congenital Heart Disease Surgery: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials Read More »

A Retrospective Analysis of Altitude Illness at the Himalayan Rescue Association Aid Post Manang (2018-2023)

Suraj Shrestha, Sanjeev Kharel, Suman Acharya, Gobi Basyal, Sanjeeb S. BhandariSuryabinayak Municipal Hospital. Mountain Medicine Society of Nepal. Maharajgunj Medical Campus. Tribhuvan University Teaching Hospital. Himalayan Rescue Association.Nepal High Altitude Medicine and BiologyHigh Alt Med Biol 2025; DOI: 10.1177/15578682251376256 AbstractIntroduction: The Himalayan Rescue Association (HRA) in Nepal has been operating high-altitude aid posts in the Himalayas to

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International Society for Heart and Lung Transplantation (ISHLT) Consensus Statement on Risk Stratification in Pulmonary Arterial Hypertension

Sandeep Sahay 1, Scott Visovatti 2, Adriano R Tonelli 3, Nelson Villasmil Hernandez 4, Eric D Austin 5, Roberto Badagliacca 6, Rolf M F Berger 7, Athénaïs Boucly 8, Yucheng Chen 9, Colin Church 10, Marion Delcroix 11, Allen D Everett 12, Harrison W Farber 13, Charles Fauvel 14, Mardi Gomberg-Maitland 15, Megan Griffiths 16, Francois Haddad 17, Yuchi Han 18, Anna Hemnes 5, Marius M Hoeper 19, Manreet K Kanwar 20, Daniel Lachant 21, Sandhya Murthy 22, Karen M Olsson 19, Ioana Preston 23, Göran Rådegran 24, Olivier Sitbon 25, Maria G Trivieri 26, Jean-Luc Vachiery 27, Rebecca Vanderpool 2, Jason Weatherald 28, R James White 21, Helen Whitford 29, Melisa Wilson 30, Raymond L Benza  Houston Methodist Hospital. Ohio State University.

International Society for Heart and Lung Transplantation (ISHLT) Consensus Statement on Risk Stratification in Pulmonary Arterial Hypertension Read More »

Outcomes of Extracorporeal Membrane Oxygenation in Patients with COVID-19 and Pulmonary Hypertension: An ELSO Registry Analysis

Raysa Morales-Demori, James Ortoleva, Sukru Aras, Marc AndersBaylor College of Medicine and Texas Children’s Hospital,. Boston Medical Center. United States Journal of Cardiovascular and Vascular AnesthesiaJ Cardiovasc Vasc Anesth 2025; DOI: 10.1053/j.jvca.2025.08.008 AbstractObjective: To describe the characteristics and outcomes of patients with COVID-19 infection with acute or chronic pulmonary hypertension (PH) supported by extracorporeal membrane oxygenation (ECMO).

Outcomes of Extracorporeal Membrane Oxygenation in Patients with COVID-19 and Pulmonary Hypertension: An ELSO Registry Analysis Read More »

Cardiac magnetic resonance in systemic sclerosis: imaging features and potential prognostic implications. A literature review

Giovanni Vitale, Matteo Colina, Domenico Attinà, Fabio Niro, Paolo OrtolaniOspedale Santa Maria della Scaletta. IRCCS Azienda Ospedaliero-Universitaria di Bologna.Italy Frontiers in MedicineFront Med 2025; 12: DOI: 10.3389/fmed.2025.1606593 AbstractSystemic sclerosis (SSc) is a chronic, multisystem disorder characterized by vascular dysfunction, immune dysregulation with production of autoantibodies, fibroblasts dysfunction and consequent abnormal collagen production, leading to progressive fibrosis

Cardiac magnetic resonance in systemic sclerosis: imaging features and potential prognostic implications. A literature review Read More »

Supravalvular aortic stenosis – Novel pathogenic ELN variant in siblings with a wide spectrum of clinical cardiovascular features and a long follow-up from infancy to adulthood

Sini Keskinen, Jussi Niemelä, Hannele Koillinen, Talvikki Boldt, Anita ArolaTurku University Hospital and University of Turku. New Children’s HospitalFinland Cardiovascular Revascularization MedicineCardiovasc Revasc Med 2025; DOI: 10.1016/j.carrev.2025.04.027 AbstractBackground: Supravalvular aortic stenosis (SVAS) is an autosomal dominantly inherited congenital cardiovascular disease caused by disruption of elastin gene (ELN), encoding elastin, an essential component of elastic arteries. It usually

Supravalvular aortic stenosis – Novel pathogenic ELN variant in siblings with a wide spectrum of clinical cardiovascular features and a long follow-up from infancy to adulthood Read More »

Four decades of heart-lung transplantation: Milestones and outcomes in advanced cardiorespiratory failure

L. Lily Rosenthal, Anna Maria Mühlbauer, Carola Grinninger, Nikolaus A. Haas, Heinrich Netz, Robert Dalla Pozza, Jürgen Hörer, Sebastian Michel, R. Schramm, D. Graetz, Christian HaglLMU University Hospital Munich. Clinic Bogen. Heart and Diabetes Centre North Rhine-Westphalia. Clinic Gauting.Germany European Society of Cardiology Heart FailureESC Heart Fail 2025; DOI: 10.1002/ehf2.15411 AbstractAims: Heart-lung transplantation (HLTx) remains a life-saving intervention

Four decades of heart-lung transplantation: Milestones and outcomes in advanced cardiorespiratory failure Read More »

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