Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease

High altitude pulmonary edema. Epidemiologic observations in Peru

Herbert N. Hultgren, Emilio A. MarticorenaStanford University School of Medicine and Veterans Administration Hospital. San Marcos University and Chulec General Hospital.United States and Peru ChestChest 1978; 74: 372-376DOI: 10.1016/S0012-3692(15)37380-3 AbstractThe incidence of high altitude pulmonary edema was examined by a survey (via questionnaire) of residents living at 3,750 meters (12,303 feet) in the mining community of […]

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Interventions for preventing high altitude illness: Part 2. Less commonly-used drugs

Alejandro G Gonzalez Garay, Daniel Molano Franco, Víctor H Nieto Estrada, Arturo J Martí-Carvajal, Ingrid Arevalo-RodriguezNational Institute of Pediatrics.Mexico Cochrane Database of Systemic ReviewsCochrane Database Syst Rev 2018; 3: DOI: 10.1002/14651858.CD012983 AbstractBackground: High altitude illness (HAI) is a term used to describe a group of mainly cerebral and pulmonary syndromes that can occur during travel to elevations

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Increased hepcidin levels in high-altitude pulmonary edema

Sandro Altamura, Peter Bärtsch, Christoph Dehnert, Marco Maggiorini, Günter Weiss, Igor Theurl, Martina U. Muckenthaler, Heimo MairbäurlUniversity Hospital Heidelberg. University Hospital Zürich. Medical University of Innsbruck. Germany, Switzerland and Austria Journal of Applied PhysiologyJ App Physiol 2015; 118: 292-298 DOI: 10.1152/japplphysiol.00940.2014 AbstractLow iron availability enhances hypoxic pulmonary vasoconstriction (HPV). Considering that reduced serum iron is caused

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SOX17 variants are associated with severe pulmonary arterial hypertension with and without congenital heart disease

Cara Morgan, Laura Southgate, Alistair Calder, Thivya Sekar, Andrew Constantine, Sadia Quyam, Richard Trembath, Shahin MoledinaGreat Ormond Street Hospital for Children. University of London, School of Health & Medical Sciences. Queen Elizabeth Hospital Birmingham. University College London. King’s College London. United Kingdom International Journal of CardiologyInt J Cardiol 2025; DOI: 10.1016/j.ijcard.2025.134114 AbstractBackground: SOX17 has recently been identified

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Exploring new heights with pulmonary functional imaging: insights into high-altitude pulmonary edema

Sean B. Fain, Marlowe W. EldridgeUniversity of Wisconsin-Madison Medical School.United States Journal of Applied PhysiologyJ Appl Physiol 2017; 122: 853-854DOI: 10.1152/japplphysiol.00168.2017 AbstractAbstract Not Available CategoryHigh Altitude Pulmonary Edema Age Focus: Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication Article Access Free PDF File

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Juvenile-onset mixed connective tissue disease: A multicenter retrospective cohort study

Kevin Chevalier, Brigitte Bader-Meunier, Isabelle Kone-Paut, Benjamin Thoreau, Marc Michel, Bertrand Godeau, Christian Agard, Thomas Papo, Karim Sacre, Rapha`ele Seror, Xavier Mariette, Patrice Cacoub, Ygal Benhamou, Mathilde Leclercq, C´ecile Goujard, Olivier Lambotte, Bernard Bonnotte, Maxime Samson, Félix Ackermann, Jean Schmidt, Pierre Duhaut, Jean-Emmanuel Kahn, Thomas Hanslik, Nathalie Costedoat-Chalumeau, Benjamin Terrier, Alexis Regent, Bertrand Dunogue, Pascal

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Meta-Analysis of Differential Gene Expression in Idiopathic Pulmonary Arterial Hypertension

Andy P. Huang, Sarah Voskamp, Ameneh A. Ebadi, Jennifer L. Liedel, Jennifer S. Nelson, Joseph KuruvillaUniversity of Central Florida. Nemours Children’s Hospital. United States Cardiovascular PathologyCardiovasc Pathol 2025;  DOI: 10.1016/j.carpath.2025.107805 AbstractBackground: Idiopathic pulmonary arterial hypertension (IPAH) is a subtype of pulmonary arterial hypertension and impacts both children and adults. IPAH has overall poor survival, highlighting the importance

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Clinical characteristics and outcomes of cardiovascular surgery and transcatheter procedures in adults with Down syndrome and congenital heart disease

Takumi Osawa, Tomoko Machino-Ohtsuka, Keitaro Kume, Takahiro Yano, Koshiro Kanaoka, Yoko Sumita, Yusuke Yano, Ruriko Numata, Naoto Kawamatsu, Hideyuki Kato, Yuji Hiramatsu, Tomoko IshizuUniversity of Tsukuba. National Cerebral and Cardiovascular Center. Japan International Journal of Cardiology Congenital Heart DiseaseInt J Cardiol Congenit Heart Dis 2025; 22: DOI: 10.1016/j.ijcchd.2025.100638 AbstractBackground: Advances in medical care have increased the number

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Congenital descending aorta to pulmonary vein fistula: an unusual cause of left ventricular dilation in a 21-year-old female

Xiang Pan, Chan Yu, Zhouhui Chen, Bowen ZhaoSir Run Run Shaw Hospital and Zhejiang University College of Medicine.China Journal of Cardiothoracic SurgeryJ Cardiothorac Surg 2025; 20: DOI: 10.1186/s13019-025-03691-5 AbstractBackground: Congenital descending aorta to pulmonary vein fistula (cDAPVF) is a rare congenital vascular malformation diagnosed in infancy and childhood. Adult cDAPVF is often asymptomatic and usually detected incidentally

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Targeting CircNLRP12 attenuates hypoxia-induced pulmonary arterial smooth muscle cell dysfunction by sponging miR-107-5p and suppressing the ITGA2-mediated FAK/PI3K/AKT pathway

Zongbin Li, Miao Zhao, Shanshan Ma, Shuyu LeiThird People’s Hospital of Xinjiang Uygur Autonomous Region. China European Journal of Medical ResearchEur J Med Res 2025; DOI: 10.1186/s40001-025-03586-0 AbstractBackground: Pulmonary arterial hypertension associated with congenital heart disease (PAH-CHD) drives lethal pulmonary vascular remodeling. While circular RNAs (circRNAs) are emerging as disease regulators, their functional roles in PAH-CHD remain

Targeting CircNLRP12 attenuates hypoxia-induced pulmonary arterial smooth muscle cell dysfunction by sponging miR-107-5p and suppressing the ITGA2-mediated FAK/PI3K/AKT pathway Read More »

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