Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease

Outcomes of pregnancy in mice with pulmonary hypertension induced by Hypoxia/SU5416

Yang Liu, Jing Deng, Yichen Zhao, Kemin Liu, Wenbo Zhang, Qiang Wang, Jiangang Wang, Chunmei PiaoBeijing Anzhen Hospital Affiliated to Capital Medical University. Yanbian University. Beijing Institute of Heart Lung and Blood Vessel Diseases. China Biochemical and Biophysical Research CommunicationsBiochem Biophys Res Commun 2023; 669: 128-133DOI: 10.1016/j.bbrc.2023.05.051 AbstractBackground: Pulmonary hypertension (PH) seriously affects the health of patients. […]

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MicroRNA and lncRNA as the Future of Pulmonary Arterial Hypertension Treatment

Łukasz Wołowiec, Martyna Medlewska, Joanna Osiak, Anna Wołowiec, Elzbieta Grzésk3 , Albert Jásniak, Grzegorz GrzéskNicolaus Copernicus University.Poland International Journal of Molecular SciencesInt J Mol Sci 2023; 24: DOI: 10.3390/ijms24119735 AbstractPulmonary hypertension (PH) is characterized by a progressive increase in pulmonary arterial pressure and pulmonary vascular resistance. In a short time, it leads to right ventricular failure

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Myeloid-derived suppressor cells and pulmonary hypertension

Hui Zhang, Qi-Wei Li, Yuan-Yuan Li, Xue Tang, Ling Gu, Han-Min LiuWest China Second University Hospital and Sichuan University. The Fifth People’s Hospital of Chengdu. China Frontiers in ImmunologyFront Immunol 2023; 14: DOI: 10.3389/fimmu.2023.1189195 AbstractPulmonary hypertension (PH) is a chronic pulmonary vascular disorder characterized by an increase in pulmonary vascular resistance and pulmonary arterial pressure. The

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Implementation of genomic medicine for rare disease in a tertiary healthcare system: Mayo Clinic Program for Rare and Undiagnosed Diseases (PRaUD)

Filippo Pinto e Vairo, Jennifer L. Kemppainen, Carolyn R. Rohrer Vitek, Denise A. Whalen, Kayla J. Kolbert, Kaitlin J. Sikkink, Sarah A. Kroc, Teresa Kruisselbrink, Gabrielle F. Shupe, Alyssa K. Knudson, Elizabeth M. Burke, Elle C. Loftus, Lorelei A. Bandel, Carri A. Prochnow, Lindsay A. Mulvihill, Brittany Thomas, Dale M. Gable, Courtney B. Graddy, Giovanna

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The perioperative use of inhaled prostacyclins in cardiac surgery: a systematic review and meta-analysis

Berend Marcus, Frederik Marynen, Steffen Fieuws, Dieter Van Beersel, Filip Rega, Steffen RexUniversitair Ziekenhuis Leuven. Katholieke Universiteit Leuven. Belgium Canadian Journal of AnaesthesiaCan J Anaesth 2023; 70: 1381-1393DOI: 10.1007/s12630-023-02520-4 AbstractPurpose: Perioperative pulmonary hypertension (PH) is an independent risk factor for morbidity and mortality in cardiac surgery. While inhaled prostacyclins (iPGI2s) are an established treatment of chronic PH,

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Metabolic reprogramming, oxidative stress, and pulmonary hypertension

Marissa D. Pokharel, David P. Marciano, Panfeng Fu, Maria Clara Franco, Hoshang Unwalla, Kim Tieu, Jeffrey R. Fineman, Ting Wang, Stephen M. BlackFlorida International University.  University of California San Francisco. United States Redox BiologyRedox Biol 2023; DOI: 10.1016/j.redox.2023.102797 AbstractMitochondria are highly dynamic organelles essential for cell metabolism, growth, and function. It is becoming increasingly clear that

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The cascade screening in heritable forms of pulmonary arterial hypertension

Nidhy P. Varghese, Akhilesh A. Padhye, Pilar L. Magoulas, George B. Mallory, Fadel E. Ruiz, Sandeep SahayBaylor College of Medicine Texas Children’s Hospital Houston. Houston Methodist Hospital. Weill Cornell Medical College.United States Pulmonary CirculationPulm Circ 2023;DOI: 10.1002/pul2.12259 AbstractHeritable pulmonary artery hypertension (HPAH) is an increasingly recognized type of pulmonary arterial hypertension, in both pediatric and adult

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Advances in epigenetic modifications of autophagic process in pulmonary hypertension

Min Mao, Shasha Song, Xin Li, Jiayao Lu, Jie Li, Weifang Zhao, Hanmin Liu, Jingxin Liu, Bin ZengWest China Second University Hospital and Sichuan University. School of Life Sciences of Fudan University. Shenzhen Technology University. Shenzhen Reyson Biotechnology Company. North China Pharmaceutical Company. Hebei Huamin Pharmaceutical Company.China Frontiers in ImmunologyFront Immunol 2023; 14:DOI: 10.3389/fimmu.2023.1206406 AbstractPulmonary hypertension

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Evaluation of the diagnostic and prognostic potential of optical coherence tomography (OCT) of the pulmonary arteries during standardised right heart catheterisation in patients with pulmonary hypertension: a cross-sectional single-centre experience

Emilie Zeiger, André Jakob, Robert Dalla Pozza, Markus Fischer, Anja Tengler, Sarah M. Ulrich, Leonie Arnold, Constance G. Weismann, Ingram Schulze-Neick, Nikolaus A. Haas, Joseph PattathuUniversity Hospital and Ludwig-Maximilians-University. Lund University and Skåne University Hospital.Germany and Sweden Cardiovascular Diagnosis and TherapyCardiovasc Diagn Ther 2023; 13: 453-464DOI: 10.21037/cdt-22-421 AbstractBackground: Pulmonary hypertension (PH) is diagnosed based on an invasive

Evaluation of the diagnostic and prognostic potential of optical coherence tomography (OCT) of the pulmonary arteries during standardised right heart catheterisation in patients with pulmonary hypertension: a cross-sectional single-centre experience Read More »

Defining the clinical validity of genes reported to cause pulmonary arterial hypertension

Carrie L. Welch, Micheala A. Aldred, Scrimmitha Balachandar, Dennis Dooijes, Christina A. Eichstaedt, Stefan Graf, Arjan C. Houweling, Rajiv D. Machado, Divya Pandya, Matina Prapa, Memoona Shaukat, Laura Southgate, Jair Tenorio-Castano, ClinGen PH VCEP, Wendy K. Chung, and Multiple Collaborators. International Consortium for Genetic Studies in Pulmonary Hypertension at the Pulmonary Vascular Research InstituteMultiple InstitutionsMultiple

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