Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease

Causal association of depression, anxiety, cognitive performance, the brain cortical structure with pulmonary arterial hypertension: A Mendelian randomization study

Zeying Zhang, Shelby Kutty, Wei Peng, Gaoming Zeng, Haiyan Luo, Zhenghui Xiao, Qiming Liu, Yunbin XiaoSecond Xiangya Hospital of Central South University. Johns Hopkins School of Medicine. Hunan Children’s Hospital. China Journal of Affective DisordersJ Affect Dis 2024;DOI: 10.1016/j.jad.2024.01.276 AbstractBackground: Patients with pulmonary arterial hypertension (PAH) often present with anxiety, depression and cognitive deterioration. Structural changes in

Causal association of depression, anxiety, cognitive performance, the brain cortical structure with pulmonary arterial hypertension: A Mendelian randomization study Read More »

Low global arginine bioavailability: a common phenomenon in pulmonary hypertension

Dunia Hatabah, Teresa De Marco, Dana P. McGlothlin, Mary Malloy, Loretta Z. Reyes, Rawan Korman, Gregory J. Kato, Claudia R. MorrisEmory University School of Medicine. University of California, San Francisco. Kaiser Permanente San Francisco. Children’s Healthcare of Atlanta. Blood Science Consulting.United States American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell

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The Paradox of Pulmonary Vascular Resistance: Restoration of Pulmonary Capillary Recruitment as a Sine Qua Non for True Therapeutic Success in Pulmonary Arterial Hypertension

David Langleben, Stylianos E. Orfanos, Benjamin D. Fox, Nathan Messas, Michele Giovinazzo, John D. CatravasJewish General Hospital and McGill University. Evangelismos Hospital and National and Kapodistrian University of Athens Medical School. Yitzchak Shamir Hospital and Tel Aviv University. Old Dominion University.Canada, Greece, Israel and United States Journal of Clinical MedicineJ Clin Med 2022; 11:DOI: 10.3390/jcm11154568 AbstractExercise-induced

The Paradox of Pulmonary Vascular Resistance: Restoration of Pulmonary Capillary Recruitment as a Sine Qua Non for True Therapeutic Success in Pulmonary Arterial Hypertension Read More »

Viewing Pulmonary Hypertension Through a Pediatric Lens

Stuti Agarwal, Jeffrey Fineman, David N. Cornfield, Cristina M. Alvira, Roham T. Zamanian, Kara Goss, Ke Yuan, Sebastien Bonnet, Olivier Boucherat, Soni Pullamsetti, Miguel A. Alcázar, Elena Goncharova, Tatiana V. Kudryashova, Mark R. Nicolls, Vinicio de Jesús PérezStanford University. University of California, San Francisco. University of Texas Southwestern. Boston Children’s Hospital. University of Laval. Max-Planck-Institute

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Isolated Partial Anomalous Pulmonary Veins: A 10-Year Experience at a Single Center

Can Jin, Yongtao Wu, Zhiyi Wang, Xiaoran Liu, Qiang WangBeijing An Zhen Hospital Affiliated with Capital University of Medical Sciences. China Journal of Surgical ResearchJ Surg Res 2024; 298: 63-70DOI: 10.1016/j.jss.2023.12.022 AbstractIntroduction: Isolated partial anomalous pulmonary venous connection (PAPVC) is difficult to diagnose, and surgical indications remain controversial. We reviewed 10 y of isolated PAPVC cases.Methods: The data

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Digital Spatial Profiling Identifies Distinct Molecular Signatures of Vascular Lesions in Pulmonary Arterial Hypertension

Rubin M. Tuder, Aneta Gandjeva, Sarah Williams, Sushil Kumar, Vitaly O. Kheyfets, Kyle Matthew Hatton-Jones, Jacqueline R. Starr, Jeong Yun, Jason Hong, Nicholas R. West, Kurt R. StenmarkUniversity of Colorado Anschutz Medical Campus School of Medicine. University of Colorado. Griffith University. Brigham and Women’s Hospital and Harvard Medical School. University of California, Los Angeles.United States

Digital Spatial Profiling Identifies Distinct Molecular Signatures of Vascular Lesions in Pulmonary Arterial Hypertension Read More »

Diagnostic Strategy for Suspected Unilateral Absence of the Pulmonary Artery

Van Luong Hoang, Viet Anh Lam, Thanh Nguyen PhamHanoi National Lung Hospital. Vin University. Hai Phong University of Medicine and Pharmacy.Vietnam Current Medical ImagingCurr Med Imag 2024; DOI: 10.2174/0115734056266404231207071244 AbstractBackground: Unilateral absence of the pulmonary artery (UAPA) is a very rare congenital anomaly.Objective: To analyze the diagnostic strategy applied to seven patients with UAPA who were examined

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Thrombin activatable fibrinolysis inhibitor plasma levels and TAFI Thr325Ile genetic polymorphism in a cohort of Egyptian sickle cell disease patients and impact on disease severity

Mona Hamdy, Iman A. Shaheen, Mohamed Khallaf, Yasmeen M. M. SelimCairo University.Egypt Pediatric Blood and CancerPediatr Blood Cancer 2024; 71:DOI: 10.1002/pbc.30959 AbstractBackground: Thrombin is a critical protease modulating thrombosis as well as inflammation, which are one of the main pathophysiological mechanisms in sickle vasculopathy, and its levels were reported to be high in sickle cell disease (SCD).

Thrombin activatable fibrinolysis inhibitor plasma levels and TAFI Thr325Ile genetic polymorphism in a cohort of Egyptian sickle cell disease patients and impact on disease severity Read More »

Susceptibility to high-altitude pulmonary edema is associated with increased pulmonary arterial stiffness during exercise

Ashley Mulchrone, H. Moulton, Marlow W. Eldridge, Naomi C. CheslerUniversity of Wisconsin-Madison.United States Journal of Applied PhysiologyJ Appl Physiol 2020; 128: 514-522DOI: 10.1152/japplphysiol.00153.2019 AbstractHigh-altitude pulmonary edema (HAPE), a reversible form of capillary leak, is a common consequence of rapid ascension to high altitude and a major cause of death related to high-altitude exposure. Individuals with a

Susceptibility to high-altitude pulmonary edema is associated with increased pulmonary arterial stiffness during exercise Read More »

Atrial Septal Defect, Pulmonary Arterial Hypertension, and Diastolic Left Heart Failure: When 3 Players Come into the Game

Tobias Rutz, John-David Aubert, Maurice Beghetti, Eric Eeckhout, Olivier Muller, Judith Bouchardy, Patrick YerlyLausanne University Hospital and University of Lausanne. Universitaire Romand de Cardiologie et Chirurgie Cardiaque Pédiatrique. Switzerland Circulation Heart FailureCirc Heart Fail 2024;DOI: 10.1161/CIRCHEARTFAILURE.123.010545 AbstractAbstract Not Available CategoryClass I. Pulmonary Hypertension Associated with Congenital Cardiovascular DiseaseClass II. Pulmonary Hypertension Associated with Left Ventricular Systolic

Atrial Septal Defect, Pulmonary Arterial Hypertension, and Diastolic Left Heart Failure: When 3 Players Come into the Game Read More »

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