No Age-Related Focus

Mitochondrial hyperfusion induces metabolic remodeling in lung endothelial cells by modifying the activities of electron transport chain complexes I and III

Manivannan Yegambaram, Xutong Sun, Qing Lu, Yan Jin, Wojciech Ornatowski, Jamie Soto, Saurabh Aggarwal, Ting Wang, Kim Tieu, Haiwei Gu, Jeffrey R. Fineman, Stephen M. BlackFlorida International University. University of Arizona. University of California San Francisco.United States Free Radical Biology and MedicineFree Radic Biol Med 2023; DOI: 10.1016/j.freeradbiomed.2023.11.008 AbstractObjective: Pulmonary hypertension (PH) is a progressive disease with […]

Mitochondrial hyperfusion induces metabolic remodeling in lung endothelial cells by modifying the activities of electron transport chain complexes I and III Read More »

The pulmonary veins

Albert L. HymanTulane University School of Medicine.United States Annual Review of MedicineAnnu Rev Med 1966; 17: 431-446DOI: 10.1146/annurev.me.17.020166.002243 AbstractAbstract Not Available CategorySegmental Pulmonary Venous Disease. Without a Focus on Pulmonary HypertensionReview Articles Concerning Pulmonary Vascular Disease Age Focus: No Age-Related Focus Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication Article Access Free

The pulmonary veins Read More »

Active response of pulmonary veins to distention of a single pulmonary vein in intact dogs

Albert L. Hyman, G. SanchezTulane University School of Medicine.United States Journal of Laboratory and Clinical MedicineJ Lab Clin Med 1969; 73: 476-485DOI: Not Available AbstractAbstract Not Available CategorySegmental Pulmonary Venous Disease. Without a Focus on Pulmonary HypertensionAnimal Models of Pulmonary Vascular Disease and Therapy Age Focus: No Age-Related Focus Fresh or Filed Publication: Filed (PHiled).

Active response of pulmonary veins to distention of a single pulmonary vein in intact dogs Read More »

CAR Selectively Enhances the Pulmonary Vasodilatory Effect of Fasudil in a Microsphere Model of Pulmonary Hypertension

Abraham Rothman, Humberto Restrepo, William N. Evans, Valeri Sarukhanov, David MannUniversity of Nevada Las Vegas. Vascular BioSciences.United States Open Respiratory Medicine JournalOpen Respir Med J 2023; DOI: 10.2174/18743064-v17-e230404-2022-19 AbstractBackground: Despite the approval of several medications for pulmonary hypertension, morbidity and mortality are unacceptably high. Systemic hypotension may limit the use of pulmonary hypertension medications.Objectives: This study aimed to

CAR Selectively Enhances the Pulmonary Vasodilatory Effect of Fasudil in a Microsphere Model of Pulmonary Hypertension Read More »

Ambulatory Seven-Day Mechanical Circulatory Support in Sheep Model of Pulmonary Hypertension and Right Heart Failure

Rei Ukita, Yatrik J. Patel, W. Kelly Wu, Sean A. Francois, Michael Cortelli Jr, Carl A. Johnson Jr, Nancy Cardwell, Jennifer R. Talackine, John W. Stokes, William Grogan, Meredith Mentz, Kaitlyn M. Tracy, Timothy R. Harris, William Tucker, Elizabeth Simonds, Caitlin T. Demarest, Keith E. Cook, David J. Skoog, Erika B. Rosenzweig, Matthew BacchettaVanderbilt University

Ambulatory Seven-Day Mechanical Circulatory Support in Sheep Model of Pulmonary Hypertension and Right Heart Failure Read More »

Observations on Resistance to the Flow of Blood to and from the Lungs

Richmond L. Moore, Carl A. L. BingerHospital of The Rockefeller Institute for Medical ResearchUnited States Journal of Experimental MedicineJ Exp Med 1927; 45: 655-671DOI: 10.1084/jem.45.4.655 Abstract1. Embolism of pulmonary arterioles and capillaries produced by the intravenous injection of starch grains results in a dilatation of the pulmonary artery and the right chambers of the heart. This

Observations on Resistance to the Flow of Blood to and from the Lungs Read More »

Loss of Prolyl Hydroxylase 1 and 2 in SM22α-Expressing Cells Prevents Hypoxia-Induced Pulmonary Hypertension

Elizabeth A. Barnes, Reiji Ito, Xibing Che, Cristina M. Alvira, David N. CornfieldStanford University.United States and Japan American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2023; DOI: 10.1152/ajplung.00428.2022 AbstractPulmonary arterial hypertension (PAH) is a disease characterized by increased vasoconstriction and vascular remodeling. Pulmonary artery smooth muscle cells (PASMC) highly

Loss of Prolyl Hydroxylase 1 and 2 in SM22α-Expressing Cells Prevents Hypoxia-Induced Pulmonary Hypertension Read More »

Circ_0068481 affects the human pulmonary artery smooth muscle cells’ progression by miR-361-3p/KLF5 axis

Hai-Rong Li, Guan-Liang Chen, Xiao-Li Fang, Xing-jiu Cai, Rong-Li Xu, Dong-Dong Li, Zhi-Wei ZhangSouthern Medical University. Hainan General Hospital and Hainan Affiliated Hospital of Hainan Medical University. Guangdong General Hospital.China American Journal of HypertensionAm J Hypertens 2023; DOI: 10.1093/ajh/hpad028 AbstractBackground: Uncontrolled proliferation of pulmonary artery smooth muscle cells (PASMCs) contributes to the pathogenesis of pulmonary arterial hypertension

Circ_0068481 affects the human pulmonary artery smooth muscle cells’ progression by miR-361-3p/KLF5 axis Read More »

Altered Smooth Muscle Cell Histone Acetylome by the SPHK2/S1P Axis Promotes Pulmonary Hypertension

A. Dushani C.U. Ranasinghe, Maggie Holohan, Kalyn M. Borger, Deborah L. Donahue, Rafael D. Kuc, Martin Gerig, Andrew Kim, Victoria A. Ploplis, Francis J. Castellino, Margaret A. SchwartzHarper Cancer Research Institute. University of Notre Dame. Indiana University School of Medicine. United States Circulation ResearchCirc Res 2023; DOI: 10.1161/CIRCRESAHA.123.322740 AbstractBackground: Epigenetic regulation of vascular remodeling in pulmonary hypertension

Altered Smooth Muscle Cell Histone Acetylome by the SPHK2/S1P Axis Promotes Pulmonary Hypertension Read More »

Restoration of Foxp3+ Regulatory T Cells by HDAC-dependent Epigenetic Modulation Plays a Pivotal Role in Resolving Pulmonary Arterial Hypertension Pathology

Chien-Nien Chen, Nabil Hajji, Fu-Chiang Yeh, Sunniyat Rahman, Souad Ali, John Wharton, Nicoleta Baxan, Lin Zhao, Chong-Yang Xie, Yi-Guan Chen, Maria G. Frid, Prakash Chelladurai, Soni Savai Pullamsetti, Kurt R. Stenmark, Martin R. Wilkins, Lan ZhaoImperial College London. Tri-Service General Hospital. University of Colorado. University Giessen Lung Centre. Max Planck Institute for Heart and Lung

Restoration of Foxp3+ Regulatory T Cells by HDAC-dependent Epigenetic Modulation Plays a Pivotal Role in Resolving Pulmonary Arterial Hypertension Pathology Read More »

Scroll to Top