Medical Therapy. Adverse Effects or Lack of Adverse Effects

Reversible severe pulmonary hypertension related to scurvy in children

Marin Satawiriya, Apichai Khongphatthanayothin, Alisa LimsuwanFaculty of Medicine Ramathibodi Hospital and Mahidol University. Bangkok Heart Hospital. Chulalongkorn University. Thailand BioMed Central Cardiovascular DisordersBMC Cardiovasc Disord 2024; 24:DOI: 10.1186/s12872-023-03629-6 AbstractBackground: Severe pulmonary hypertension (PH) in childhood is rare and can manifest as a life-threatening episode. We present 2 children with restrictive dietary habits with severe pulmonary hypertension secondary […]

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Use of Metformin in Pulmonary Vein Stenosis after TAPVR Repair

Edward C. Kirkpatrick, Michael E. Mitchell, MD, William G. Thilly, Joseph Cava, Aoy Tomita-Mitchell, Elena V. GostjevaChildren’s Hospital of Wisconsin and Medical College of Wisconsin. Massachusetts Institute of Technology. United States Global Pediatric HealthGlob Pediatr Health 2020;DOI: 10.1177/2333794X20958924 AbstractAbstract Not Available CategoryClass II. Pulmonary Hypertension Associated with Pulmonary Vein StenosisMedical Therapy. Efficacy or Lack of EfficacyMedical Therapy. Adverse Effects or Lack of Adverse Effects Age Focus: Pediatric Pulmonary

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A prospective phase II trial of vinblastine and methotrexate in multivessel intraluminal pulmonary vein stenosis in infants and children

Maliha Rehman, Kathy J. Jenkins, Amy L. Juraszek, Jean A. Connor, Kimberlee Gauvreau, Muhammad Muneeb, Laureen M. Sena, Steven D. Colan, Terry Saia, Mark W. KieranChildren’s Hospital, Boston.United States Congenital Heart DiseaseCongenit Heart Dis 2011; 6: 608-623DOI: 10.1111/j.1747-0803.2011.00574.x AbstractObjective: To determine the safety and efficacy of the chemotherapeutic agents vinblastine and methotrexate in the treatment of children

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Selexipag for the Treatment of Pediatric Pulmonary Hypertension: A Systematic Review

Meng Li, Lin Liu, Cong Liu, Zebin Chen, Weibin Li, Xuejuan Li, Xiaopeng Ma, Yumao ZhangShenzhen Children’s Hospital. Eighth Affiliated Hospital and Sun Yat-sen University.China Clinical TherapeuticsClin Ther 2023; DOI: 10.1016/j.clinthera.2023.09.026 AbstractPurpose: To systematically evaluate the safety, dosing regimen, and efficacy of selexipag for pediatric patients with pulmonary hypertension (PH).Methods: A literature search of the electronic databases of

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Rapidly Progressive Idiopathic Pulmonary Arterial Hypertension in a Paediatric Patient Treated with Lung Transplantation

Filip Baszkowski, Weronika Pelczar-Płachta, Nikola Pempera, Sylwia Sławek-Szmyt, Marta Kałuzna-Oleksy, Maciej Lesiak, Waldemar BobkowskiPoznan University of Medical Sciences.Poland DiagnosticsDiagnostics 2023; DOI: 10.3390/diagnostics13203185 AbstractPulmonary arterial hypertension (PAH) is a rare heterogeneous disorder in the paediatric population which is mostly associated with congenital heart disease. The management of paediatric idiopathic PAH (IPAH) is difficult due to insufficient comparative

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Home-inhaled nitric oxide in a child with pulmonary arterial hypertension associated with post-operative pulmonary venous obstruction

Yuichiro Sugitani, Jun Muneuchi, Mamie WatanabeKyushu Hospital and Japan Community Healthcare Organization.Japan Cardiology in the YoungCardiol Young 2023; DOI: 10.1017/S1047951123003591 AbstractHome-inhaled nitric oxide therapy was effective and feasible in the patients with intractable pulmonary arterial hypertension. We present the case of a child with severe pulmonary arterial hypertension associated with post-operative pulmonary venous obstruction who was

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Comparison of mortality and short-term outcomes between classic, intubation-surfactant-extubation, and less invasive surfactant administration methods of surfactant replacement therapy

Seung Yeon Kim, Jiseun Lim, Gyu-Hong ShimNowon Eulji Medical Center and Eulji University School of Medicine. Inje University Sanggye Paik Hospital.Republic of Korea Frontiers in PediatricsFront Pediatr 2023; 11DOI: 10.3389/fped.2023.1197607 AbstractBackground: Intubation-Surfactant-Extubation (InSurE) and less invasive surfactant administration (LISA) are alternative surfactant replacement therapy methods for reducing the complications associated with invasive mechanical ventilation. This study aimed

Comparison of mortality and short-term outcomes between classic, intubation-surfactant-extubation, and less invasive surfactant administration methods of surfactant replacement therapy Read More »

Comparing the efficacy and safety of low, medium, and high dosages of selexipag for treating pulmonary hypertension: A systematic review and meta-analysis

Shang Wang, Yi Yan, Jian Zhang, Ping Yuan, Ci-Jun Luo, Hong-Ling Qiu, Hui-Ting Li, Lan Wang, Tian-Lan Li, Rong Jianghanghai Pulmonary Hospital, School of Medicine, Tongji University. Shanghai Children’s Medical Center, National Children’s Medical Center, Shanghai Jiaotong University School of Medicine. The Second Affiliated Hospital of Chengdu Medical College. The Affiliated Hospital of Qingdao University.China

Comparing the efficacy and safety of low, medium, and high dosages of selexipag for treating pulmonary hypertension: A systematic review and meta-analysis Read More »

Acute pulmonary edema caused by epoprostenol infusion in a child with scimitar syndrome and pulmonary hypertension

Christian von Schnakenburg, Matthias Peuster, Kambiz Norozi, Markus Roebl, Michael Maibohm, Armin Wessel, Armin Christoph FinkGeorg-August-Universitaet Goettingen.Germany Pediatric Critical Care MedicinePediatr Crit Care Med 2003; 4: 111-114DOI: 10.1097/00130478-200301000-00023 AbstractIntroduction: Intravenous epoprostenol is frequently administered in adults and children for treatment of pulmonary hypertension. Although generally safe, pulmonary edema has been described in a few case reports of

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Safety and tolerability of continuous inhaled iloprost in critically ill pediatric pulmonary hypertension patients: A retrospective case series

Elizabeth Colglazier, Angelica J. Ng, Clair Parker, David Woolsey, Raymond Holmes, Allison Dsouza, Jasmine Becerra, Leah Stevens, Hythem Nawaytou, Roberta L. Keller, Jeffrey R. FinemanUniversity of California, San Francisco. Merck Sharp & Dohme LLC. Benioff Children’s Hospital. United States Pulmonary CirculationPulm Circ 2023; 13DOI: 10.1002/pul2.12289 AbstractInhaled iloprost (iILO) has shown efficacy in treating patients with hypoxic

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