Review Articles Concerning Pulmonary Vascular Disease

Inhaled nitric oxide use in newborns

Souvik Mitra, Gabriel AltitCanadian Paediatric Society.Canada Paediatrics and Child HealthPaediatr Child Health 2023; 28: 119-127DOI: 10.1093/pch/pxac107 AbstractInhaled nitric oxide (iNO), a selective pulmonary vasodilator, is used as a therapeutic modality in infants with hypoxemic respiratory failure (HRF) associated with persistent pulmonary hypertension of the newborn (PPHN). iNO should ideally be initiated following echocardiographic confirmation of PPHN. […]

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Management of pulmonary arterial hypertension during pregnancy

Kaushiga Krishnathasan, Andrew Constantine, Isma Rafiq, Ana Barradas Pires, Hannah Douglas, Laura C. Price, Konstantinos DimopoulosRoyal Brompton Hospital and Royal Brompton & Harefield Hospitals. Imperial College. St Thomas’ Hospital. King’s College.United Kingdom Expert Review of Respiratory MedicineExpert Rev Respir Med 2023; 17: 413-423DOI: 10.1080/17476348.2023.2210838 AbstractIntroduction: Pulmonary arterial hypertension (PAH) is defined as a mean pulmonary artery pressure

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Pulmonary Hypertension in Chronic Lung Diseases: What Role Do Radiologists Play?

Adele Valentini, Paola Franchi, Giuseppe Cicchetti, Gaia Messana, Greta Chiffi, CeciliaStrappa, Lucio Calandriello, Annemiliadel Ciello, Alessandra Farchione, Lorenzo Preda, Anna Rita LariciFondazione IRCCS Policlinico San Matteo. G. Mazzini Hospital. Fondazione Policlinico Universitario. University of Pavia. Università Cattolica del Sacro Cuore. Italy DiagnosticsDiagnostics 2023; 13: DOI: 10.3390/diagnostics13091607 AbstractPulmonary hypertension (PH) is a pathophysiological disorder, defined by a

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Unique Pulmonary Hypertensive Vascular Diseases Associated with Heart and Lung Developmental Defects

Hidekazu Ishida, Jun Maeda, Keiko Uchida, Hiroyuki YamagishiOsaka University Graduate School of Medicine. Tokyo Metropolitan Children’s Medical Center. Keio University of Medicine and Health Center.Japan Journal of Cardiovascular Development and DiseaseJ Cardiovasc Dev Dis 2023; DOI: 10.3390/jcdd10080333 AbstractAlthough pediatric pulmonary hypertension (PH) shares features and mechanisms with adult PH, there are also some significant differences between

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MicroRNA and lncRNA as the Future of Pulmonary Arterial Hypertension Treatment

Łukasz Wołowiec, Martyna Medlewska, Joanna Osiak, Anna Wołowiec, Elzbieta Grzésk3 , Albert Jásniak, Grzegorz GrzéskNicolaus Copernicus University.Poland International Journal of Molecular SciencesInt J Mol Sci 2023; 24: DOI: 10.3390/ijms24119735 AbstractPulmonary hypertension (PH) is characterized by a progressive increase in pulmonary arterial pressure and pulmonary vascular resistance. In a short time, it leads to right ventricular failure

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Pulmonary vascular disease as a complication of pediatric congenital heart diseases

Julie Wacker, Raphael Joye, Leon Genecand, Frederic Lador, Maurice BeghettiGeneva University Hospitals. Centre Universitaire Romand de Cardiologie et Chirurgie Cardiaque Pédiatrique.Switzerland Translational PediatricsTransl Pediatr 2023; 12: 1041-1052DOI: 10.21037/tp-23-64 AbstractCongenital and acquired heart diseases can cause pulmonary hypertension (PH) in children, either by increasing pulmonary blood flow (PBF), left atrial pressure (LAp), and/or pulmonary vascular resistance (PVR).

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Myeloid-derived suppressor cells and pulmonary hypertension

Hui Zhang, Qi-Wei Li, Yuan-Yuan Li, Xue Tang, Ling Gu, Han-Min LiuWest China Second University Hospital and Sichuan University. The Fifth People’s Hospital of Chengdu. China Frontiers in ImmunologyFront Immunol 2023; 14: DOI: 10.3389/fimmu.2023.1189195 AbstractPulmonary hypertension (PH) is a chronic pulmonary vascular disorder characterized by an increase in pulmonary vascular resistance and pulmonary arterial pressure. The

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Metabolic reprogramming, oxidative stress, and pulmonary hypertension

Marissa D. Pokharel, David P. Marciano, Panfeng Fu, Maria Clara Franco, Hoshang Unwalla, Kim Tieu, Jeffrey R. Fineman, Ting Wang, Stephen M. BlackFlorida International University.  University of California San Francisco. United States Redox BiologyRedox Biol 2023; DOI: 10.1016/j.redox.2023.102797 AbstractMitochondria are highly dynamic organelles essential for cell metabolism, growth, and function. It is becoming increasingly clear that

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Advances in epigenetic modifications of autophagic process in pulmonary hypertension

Min Mao, Shasha Song, Xin Li, Jiayao Lu, Jie Li, Weifang Zhao, Hanmin Liu, Jingxin Liu, Bin ZengWest China Second University Hospital and Sichuan University. School of Life Sciences of Fudan University. Shenzhen Technology University. Shenzhen Reyson Biotechnology Company. North China Pharmaceutical Company. Hebei Huamin Pharmaceutical Company.China Frontiers in ImmunologyFront Immunol 2023; 14:DOI: 10.3389/fimmu.2023.1206406 AbstractPulmonary hypertension

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Defining the clinical validity of genes reported to cause pulmonary arterial hypertension

Carrie L. Welch, Micheala A. Aldred, Scrimmitha Balachandar, Dennis Dooijes, Christina A. Eichstaedt, Stefan Graf, Arjan C. Houweling, Rajiv D. Machado, Divya Pandya, Matina Prapa, Memoona Shaukat, Laura Southgate, Jair Tenorio-Castano, ClinGen PH VCEP, Wendy K. Chung, and Multiple Collaborators. International Consortium for Genetic Studies in Pulmonary Hypertension at the Pulmonary Vascular Research InstituteMultiple InstitutionsMultiple

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