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Detection of pulmonary hypertension in preterm infants with bronchopulmonary dysplasia using oxygen saturation data

Pravitha Ramanand, Premananda Indic, Samuel J. Gentle, Namasivayam AmbalavananUniversity of Texas at Tyler. University of Alabama at Birmingham.United States Pediatric ResearchPediatr Res 2025; DOI: 10.1038/s41390-025-03891-8 AbstractBackground: Pulmonary hypertension (PH) complicates the clinical course of bronchopulmonary dysplasia (BPD) in preterm infants, increasing risk of mortality and other morbidities. Early detection of PH may provide the clinical opportunity for […]

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Infants With a Congenital Diaphragmatic Hernia Had Favourable Pulmonary Hypertension Outcomes at 1 Year of Age

Alice Dirick, Marilyne Levy, Kelly Mellul, Maxime Coignard, Naziha Khen-Dunlop, Alexandre Lapillonne Julien Stirnemann, Elsa Kermorvant-DucheminNecker-Enfants Malades Hospital. France Acta PediatricaActa Pediatr 2025; DOI: 10.1111/apa.70019 AbstractAim: Pulmonary hypertension is frequent in neonates with a congenital diaphragmatic hernia, but long-term data have been scarce. Our aim was to examine its prevalence, evolution and management and identify factors associated

Infants With a Congenital Diaphragmatic Hernia Had Favourable Pulmonary Hypertension Outcomes at 1 Year of Age Read More »

TGFBI regulates pulmonary vascular remodeling through endothelial-to-mesenchymal transition in pulmonary arterial hypertension

Da Eun Roh, Na Rae Park, Bo Geum Choi, Youra Kang, Jung-Eun Kim, Yeo Hyang KimKyungpook National University, Kyungpook National University Children’s Hospital and Kyungpook National University Hospital. Republic of Korea Biochemical and Biophysical Research CommunicationsBiochem Biophys Res Commun 2025; 751: DOI: 10.1016/j.bbrc.2025.151435 AbstractPulmonary arterial hypertension (PAH) is a progressive disorder characterized by elevated pulmonary artery

TGFBI regulates pulmonary vascular remodeling through endothelial-to-mesenchymal transition in pulmonary arterial hypertension Read More »

Continuous positive airway pressure versus conventional oxygen therapy in meconium aspiration syndrome: a randomized controlled trial

Arifa Mustaqeem, Anita Yadav, Jogender Kumar, Pradeep DebataVardhman Mahavir Medical College and Safdarjung Hospital. Post Graduate Institute of Medical Education and Research. India Journal of Tropical PediatricsJ Trop Pediatr 2025; 71: DOI: 10.1093/tropej/fmaf002 AbstractNeonates with meconium aspiration syndrome (MAS) frequently require respiratory support. However, the initial mode of respiratory support in these patients remains unclear. We

Continuous positive airway pressure versus conventional oxygen therapy in meconium aspiration syndrome: a randomized controlled trial Read More »

MiR-25-3p regulates pulmonary arteriovenous malformation after Glenn procedure in patients with univentricular heart via the PHLPP2-HIF-1α axis

Junpei Kawamura, Munekazu Yamakuchi, Kentaro Ueno, Teruto Hashiguchi, Yasuhiro OkamotoKagoshima University. Japan Scientific ReportsSci Rep 2025; 15: DOI: 10.1038/s41598-025-88840-5 AbstractThe detailed mechanism of pulmonary arteriovenous malformations after Glenn surgery (G-PAVMs) in cyanotic congenital heart disease (CHD) remains unclear. Microarray in situ hybridization was performed to assess the miRNA (miRNA) profiles of serum from pediatric patients (0-6

MiR-25-3p regulates pulmonary arteriovenous malformation after Glenn procedure in patients with univentricular heart via the PHLPP2-HIF-1α axis Read More »

Unusual presentation of anomalous origin of the right pulmonary artery from the ascending aorta: case report

Mohamed Elhudairy, Naif Alkhushi, Osman Al‑Radi, Khadijah Maghrabi, Gaser AbdelmohsenKing Abdul-Aziz University. Kasr Al Ainy School of Medicine and Cairo University.Saudi Arabia and Egypt Egypt Heart JournalEgypt Heart J 2025; 77: DOI: 10.1186/s43044-025-00614-6 AbstractBackground: Anomalous origin of the right pulmonary artery (AORPA) from the ascending aorta is a rare congenital anomaly, representing approximately 0.12% of all congenital

Unusual presentation of anomalous origin of the right pulmonary artery from the ascending aorta: case report Read More »

Embolotherapy for pulmonary arteriovenous malformations in the pediatric population with hereditary hemorrhagic telangiectasias – a retrospective case series

Haseeb Mukhtar, Vivek Iyer, Nadir Demirel, Emily C. Bendel, Haraldur Bjarnason, Sanjay MisraMayo Clinic.United States Journal of Vascular and Interventional RadiologyJ Vasc Interv Radiol 2025; DOI: 10.1016/j.jvir.2025.01.047 AbstractPurpose: To document the outcomes of embolotherapy for pulmonary arteriovenous malformation (pAVM) management, and investigate factors associated with pAVM persistence after embolotherapy in pediatric patients with hereditary hemorrhagic telangiectasia (HHT).Materials

Embolotherapy for pulmonary arteriovenous malformations in the pediatric population with hereditary hemorrhagic telangiectasias – a retrospective case series Read More »

Inhalation of the Novel Tryptophan Hydroxylase 1 Inhibitor TPT-004 Alleviates Pulmonary Arterial Hypertension in Rats

Ekaterina Legchenko, Philippe Chouvarine, Klea Hysko, Fatimunnisa Qadri, Radoslw Wesolowski, Edgar Specker, Silke Glage, Martin Meier, Katharina Schwarz, Joerg Heineke, Gerhard Pohlmann, Mehmet Ramazanoglu, Michael Bader, Georg HansmannHannover Medical School. Heidelberg University Medical Faculty Mannheim. Max-Delbrück-Center for Molecular Medicine. Leibniz-Forschungsinstitut für Molekulare Pharmakologie. Fraunhofer Institute for Toxicology and Experimental Medicine. Max Delbrück Center for Molecular

Inhalation of the Novel Tryptophan Hydroxylase 1 Inhibitor TPT-004 Alleviates Pulmonary Arterial Hypertension in Rats Read More »

Characterization of Intracardiac Flow in the Right Ventricle With Pressure and Volume Overload in Children

Yasunobu Hayabuchi, Yukako HommaTokushima University.Japan Cardiology ResearchCardiol Res 2025; 16: 22-32DOI: 10.14740/cr2009 AbstractBackground: Blood flow visualization using vector flow mapping (VFM) holds potential as a novel indicator of right ventricular (RV) function.Methods: This study included 12 patients with atrial septal defect (ASD group, mean (± standard deviation) age: 6.2 ± 1.5 years), six patients with pulmonary hypertension (PH

Characterization of Intracardiac Flow in the Right Ventricle With Pressure and Volume Overload in Children Read More »

Lung ultrasound to evaluate the outcome and prognosis of transient tachypnea of the newborn

Peng Jiang, Jing Wei, Meiying HanLiaocheng People’s Hospital.China Frontiers in PediatricsFront Pediatr 2025; 12:  DOI: 10.3389/fped.2024.1536992 AbstractBackground/objectives: Transient tachypnea of the newborn (TTN) is generally self-limiting. The increasing incidence of severe cases and lack of comprehensive studies on its clinical outcomes and influencing factors highlight the need for improved diagnostic and monitoring tools. This study aimed to

Lung ultrasound to evaluate the outcome and prognosis of transient tachypnea of the newborn Read More »

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