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Infant lung transplantation: First German experience including two cases of ABO blood group incompatible transplantations

Anna Katharina Zürn, Nicolaus Schwerk, Carsten Müller, Gregor Warnecke, Jawad Salman, Michael Sasse, Harald Köditz, Thomas Jack, Bettina Bohnhorst, Gesine Hansen, Oliver Keil, Katja Nickel, Dmitry Bobylev, Fabio Ius, Julia CarlensHannover Medical School. University Hospital of Schleswig-Holstein. Germany Journal of Heart and Lung Transplantation OpenJHLT Open 2025; 9: DOI: 10.1016/j.jhlto.2025.100251 AbstractBackground: Infant lung transplantation (LuTx) has been […]

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The nitrofen/bisdiamine murine model of congenital diaphragmatic hernia has a pulmonary hypertension vascular phenotype consistent with human CDH

Cailin R. Gonyea, Yuanjun Shen, Katherine M. Nelson, Rylie N. Bird, Rachel M. Gilbert, Oluyinka O. Olutoye II, Sundeep G. Keswani, Jason P. GleghornUniversity of Delaware. Baylor College of Medicine.United States American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2025; DOI: 10.1152/ajplung.00233.2024 AbstractCDH-associated pulmonary hypertension (CDH-PH) has severe implications

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The molecular mechanisms of IUGR programmed adulthood cardiovascular disease

Ting Wu, Wen Zhang, Yangong Wang, Hong Luo, Yifei LiWest China Second University Hospital and Sichuan University. Fudan University. China Frontiers in Cell and Developmental BiologyFront Cell Dev Biol 2025; 13: DOI: 10.3389/fcell.2025.1589038 AbstractIntrauterine growth restriction (IUGR) is secondary to several maternal and fetal adverse conditions. Recently, there is a convincing association between the onset of

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TCF7 enhances pulmonary hypertension by boosting stressed natural killer cells and their interaction with pulmonary arterial smooth muscle cells

Li-Wei Wu, Min Chen, Dai-Ji Jiang, Chen-Yu Jiang, Yi-Wei Liu, Bei Feng, Chen-Fei Shi, Xu Huang, Xu Zhang, Xiao-He Xu, Xing-Liang Zhou, Yi Shen, Tian-Yu Liu, Lin-Cai Ye, Yang-Yang He, Hao Zhang, Yi YanShanghai Children’s Medical Center, National Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Second Affiliated Hospital, Yuying Children’s Hospital

TCF7 enhances pulmonary hypertension by boosting stressed natural killer cells and their interaction with pulmonary arterial smooth muscle cells Read More »

Bronchopulmonary dysplasia with pulmonary hypertension associates with semaphorin signaling loss and functionally decreased FOXF1 expression

Shawyon P. Shirazi, Nicholas M. Negretti, Christopher S. Jetter, Alexandria L. Sharkey, Shriya Garg, Meghan E. Kapp, Devan Wilkins, Gabrielle Fortier, Saahithi Mallapragada, Nicholas E. Banovich, Laurie C. Eldredge, Gail H. Deutsch, Christopher V. E. Wright, David B. Frank, Jonathan A. Kropski, Jennifer M. S. SucreVanderbilt University Medical Center and Vanderbilt University. Translational Genomics Research

Bronchopulmonary dysplasia with pulmonary hypertension associates with semaphorin signaling loss and functionally decreased FOXF1 expression Read More »

Scurvy, all the faces you can see: our experience and review of the literature

Fabio Toscano, Giuseppina Zirilli, Simone Foti Randazzese, Mariagrazia Carlino, Romina Gallizzi, Malgorzata Wasniewska, Mariella ValenziseUniversity of Messina. Magna Graecia University of Catanzaro.Italy Italian Journal of PediatricsItal J Pediatr 2025; 51: DOI: 10.1186/s13052-025-02014-7 AbstractBackground: In the recent past an incremental incidence of scurvy has been reported in the pediatric population, especially in children with neuropsychiatric disorders and a

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Clinical Phenotypes of a Pediatric Cohort with GDF2-Related Hereditary Hemorrhagic Telangiectasia

Owen Oliver, Allison D. Britt, Alexandra J. Borst, Elizabeth Goldmuntz, Nihal Bakeer, Shih-shan Lang, Stephanie Fuller, Arastoo Vossough, Lauren A. BeslowChildren’s Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania. United States Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14103359 AbstractBackground/Objectives: Pathogenic variants in the growth differentiation factor 2 (GDF2) gene

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Efficacy of Intravascular Therapeutic Hypothermia for Moderate to Severe Hypoxic-Ischemic Encephalopathy

Tomonori Kurimoto, Takuya Tokuhisa, Itaru Hayasaka, Tsuyoshi Yamamoto, Eiji Hirakawa, Hiroshi Ohashi, Masaya Kibe, Asataro Yara, Takatsugu Maeda, Masato Kamitomo, Satoshi IbaraKagoshima City Hospital. Nikko Memorial Hospital. Japan ChildrenChildren 2025; 12: DOI: 10.3390/children12050605 AbstractBackground/objectives: Hypoxic-ischemic encephalopathy (HIE), affecting 1.3-1.7/1000 live births, is treated with conventional therapeutic hypothermia (TH) but carries significant mortality and neurological impairment. Here, we

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Sex differences in the risk of bronchopulmonary dysplasia and pulmonary hypertension: a Bayesian meta-analysis

Elke Van Westering-Kroon, Tamara M. Hundscheid, Karen Van Mechelen, Frantisek Bartos, Steven H. Abman, Eduardo VillamorMosaKids Children’s Hospital, Maastricht University Medical Centre and Maastricht University. University of Amsterdam. University of Colorado Anschutz School of Medicine and Children’s Hospital Colorado. Netherlands and United States Pediatric ResearchPediatr Res 2025; DOI: 10.1038/s41390-025-04145-3 AbstractBackground: Bronchopulmonary dysplasia (BPD) is generally considered to

Sex differences in the risk of bronchopulmonary dysplasia and pulmonary hypertension: a Bayesian meta-analysis Read More »

Common shunt lesions with pulmonary hypertension-who will benefit from surgery?

Shine Kumar, Raman Krishna KumarAmrita Hospital and Amrita Vishwa Vidyapeetham University.India Indian Journal of Thoracic and Cardiovascular SurgeryInd J Thorac Cardiovasc Surg 2025; 41: 718-729DOI: 10.1007/s12055-024-01786-7 AbstractLeft to right shunts comprise a specific group of congenital heart disease, when identified and treated on time result in excellent outcomes. However, a proportion of these defects do not

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