Fresh (PHresh). Less than 1-2 years since publication

Decreased smooth muscle cells and fibrous thickening of the tunica media in peripheral pulmonary artery stenosis in Alagille syndrome

Yosuke Ogawa, Amane Yamamoto, Sho Yamazawa, Masako Ikemura, Yasutaka Hirata, Ryo InuzukaUniversity of Tokyo Hospital.Japan Cardiovascular PathologyCardiovasc Pathol 2025; DOI: 10.1016/j.carpath.2024.107677 AbstractAlagille syndrome is caused by mutations in genes involved in NOTCH signaling, specifically JAG1 and NOTCH2, and is associated with a high rate of peripheral pulmonary artery stenosis. In this study, we report the case […]

Decreased smooth muscle cells and fibrous thickening of the tunica media in peripheral pulmonary artery stenosis in Alagille syndrome Read More »

Chronic cyanosis since infancy: Unveiling a giant right pulmonary arteriovenous malformation

Dian Komalaa, Harry Galuh Nugrahaa, Firman Ramadhana, Rais Khairuddina, Rahmat Budi Kuswiyantob, Putria Rayani ApandiUniversitas Padjadjaran.Indonesia Radiology Case ReportsRadiol Case Rep 2025; 20: 5353-5356DOI: 10.1016/j.radcr.2025.06.084 AbstractGiant pulmonary arteriovenous malformations (PAVMs) are rare vascular anomalies involving direct connections between pulmonary arteries and veins, leading to right-to-left shunting and systemic hypoxemia. While small PAVMs may be asymptomatic, larger

Chronic cyanosis since infancy: Unveiling a giant right pulmonary arteriovenous malformation Read More »

Early postnatal right-to-left patent ductus arteriosus shunting and severe outcomes in neonates with congenital diaphragmatic hernia: a retrospective cohort study

Jung Il Kwak, Juhee Park, Mi Jin Kim, Kyusang Yoo, Bo Kyeong Jin, Tae-Gyeong Kim, Joo Hyung Roh, Ha Na Lee, Keon Hee Seol, Chae Young Kim, Soo Hyun Kim, Jiyoon Jeong, Byong Sop Lee, Euiseok JungAsan Medical Center Children’s Hospital and University of Ulsan College of Medicine. BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-05986-x

Early postnatal right-to-left patent ductus arteriosus shunting and severe outcomes in neonates with congenital diaphragmatic hernia: a retrospective cohort study Read More »

Large Patent Ductus Arteriosus in an Adult With Severe Pulmonary Hypertension and Polycythemia: PDA With Severe Pulmonary Hypertension

Tyler L. Langenfeld, Maram Sati, Martin L. Bocks, Arpit K. AgarwalRainbow Babies and Children’s Hospital. United States Journal of the American College of CardiologyJACC Case Rep 2025; 30: DOI: 10.1016/j.jaccas.2025.104677 AbstractBackground: Patent ductus arteriosus (PDA) is one of the most common cardiac abnormalities in children, but in rare cases it can go undiagnosed into adulthood until symptoms

Large Patent Ductus Arteriosus in an Adult With Severe Pulmonary Hypertension and Polycythemia: PDA With Severe Pulmonary Hypertension Read More »

General and Emergency Presentations of Children with Congenital Heart Defect and Factors Affecting it as Seen in A Tertiary Health Institution in Enugu

I. O. Arodiwe, I. A. Nwafor, F. A. Ujunwa, B. O. Edulu, J. M. Chinawa, T. A. Oguonu, N. Ezemba, J. C. EzeUniversity of Nigeria, Enugu Campus.Nigeria West Africa Journal of MedicineWest Africa J Med 2025; 42: 202-207DOI: Not Available AbstractBackground and objectives: The pattern of emergency presentations in children with congenital heart disease (CHD) is

General and Emergency Presentations of Children with Congenital Heart Defect and Factors Affecting it as Seen in A Tertiary Health Institution in Enugu Read More »

Inflammatory Markers During Extracorporeal Membrane Oxygenation in Neonates With Congenital Diaphragmatic Hernia

Friederike M. Krechel, Judith Leyens, Eva Schoenenborn, Ramona Dolscheid-Pommerich, Bartolomeo Bo, Tamene Melaku, Christoph Berg, Andreas Mueller, Florian KipfmuellerChildren’s Hospital, University Hospital Bonn and University of Bonn. British Colombia Women’s and Children’s Hospital and University of British Colombia. University Hospital Cologne. University Medical Center Mannheim and University of Heidelberg.Germany and Canada American Society of Artificial

Inflammatory Markers During Extracorporeal Membrane Oxygenation in Neonates With Congenital Diaphragmatic Hernia Read More »

Case Report: Non-reactive vasoreactivity testing in a patient with patent ductus arteriosus with pulmonary hypertension: is there still a way to turn things around?

Sisca Natalia Siagian, Elsa Hedia Panjaitan, Pandu Prasetyo NugrohoUniversitas Indonesia.Indonesia Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2025; 12: DOI: 10.3389/fcvm.2025.1569963 AbstractBackground: Recent guidelines recommend patent ductus arteriosus (PDA) closure in adults based on hemodynamic criteria, such as pulmonary vascular resistance (PVR) and flow ratio (Qp:Qs). However, additional parameters like acute vasoreactivity testing (AVT) and closure testing, though

Case Report: Non-reactive vasoreactivity testing in a patient with patent ductus arteriosus with pulmonary hypertension: is there still a way to turn things around? Read More »

Less is More: ECMO Utilization and Outcomes in Congenital Diaphragmatic Hernia

Anastasia M. Kahan, Sommer Glasgow, Bradley A. Yoder, Michelle Yang, Christian C. Yost, Kelsea Peterson, Jack H. Scaife, Christopher E. Clinker, Erica Arnold, Stephen J. Fenton, Zachary J. Kastenberg, Robert A. Swendiman, Scott S. Short, Katie W. RussellUniversity of Utah.United States Journal of Pediatric SurgeryJ Pediatr Surg 2025; DOI: 10.1016/j.jpedsurg.2025.162571 AbstractPurpose: Infants with congenital diaphragmatic hernia (CDH)

Less is More: ECMO Utilization and Outcomes in Congenital Diaphragmatic Hernia Read More »

Persistent Pulmonary Hypertension Among Infants Undergoing Therapeutic Hypothermia for Hypoxic Ischemic Encephalopathy: A Systematic Review and Meta-Analysis

Rashida Javed, Tim J. Van Hasselt, Narasimha Rao, Harsha GowdaNorthampton General Hospital. University of Leicester. Madinat Zayed Hospital. University Hospitals Birmingham.United Kingdom and United Arab Emiretes Therapeutic Hypothermia and Temperature ManagementTher Hypothermia Temp Manag 2025; DOI: 10.1177/21537658251370950 AbstractTo perform a systematic review and meta-analysis to examine the association between persistent pulmonary hypertension (PPHN) and receipt of

Persistent Pulmonary Hypertension Among Infants Undergoing Therapeutic Hypothermia for Hypoxic Ischemic Encephalopathy: A Systematic Review and Meta-Analysis Read More »

Clinical and molecular spectrum of patients with methylmalonic acidemia and homocysteinemia complicated by cardiovascular manifestations

Wanqing Zhao, Yanan Zhang, Yalei Pi, Yuqian Li, Huifeng ZhangSecond Hospital of Hebei Medical University. China Orphanet Journal of Rare DiseaseOrphanet J Rare Dis 2025; DOI: 10.1186/s13023-025-03907-w AbstractBackground: To investigate the clinical characteristics, treatment response, and prognosis of patients with methylmalonic acidemia (MMA) and homocysteinemia complicated by cardiovascular manifestations and to raise awareness regarding MMA and homocysteinemia.Methods: A

Clinical and molecular spectrum of patients with methylmalonic acidemia and homocysteinemia complicated by cardiovascular manifestations Read More »

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