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Global Burden of Pediatric Pulmonary Arterial Hypertension, 1990-2021: A Systematic Analysis from the Global Burden of Disease Study 2021

Taixiang Liu, Xiaoliang Liu, Chenhong Wang, Jinxin Zheng, Liping Shi, Zheng ChenChildren’s Hospital, Zhejiang University School of Medicine. West China Second University Hospital, Sichuan University. Shanghai Jiao Tong University School of Medicine. China Pediatric CardiologyPediatr Cardiol 2025; DOI: 10.1007/s00246-025-04009-x AbstractPediatric pulmonary arterial hypertension (PAH) remains a critical global health threat characterized by disparities in burden driven […]

Global Burden of Pediatric Pulmonary Arterial Hypertension, 1990-2021: A Systematic Analysis from the Global Burden of Disease Study 2021 Read More »

What is the role of echocardiography in newborns with CDH?

María V. Fraga, Gabriel Altit, Bradley A. Yoder, Shazia BhombalChildren’s Hospital of Philadelphia, Perelman School of Medicine and University of Pennsylvania. McGill University. University of Utah School of Medicine. Children’s Healthcare of Atlanta/Emory University.United States and Canada Seminars in Fetal and Neonatal MedicineSemin Fetal Neonatal Med 2025;DOI: 10.1016/j.siny.2025.101657 AbstractCongenital diaphragmatic hernia (CDH) is associated with high

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Fetal therapies in congenital diaphragmatic hernia: a review of possibilities and practical challenges

Adriana Dekirmendjian, Fabian Doktor, Lina Antounians, Augusto ZaniUniversity of Toronto and Hospital for Sick Children. St. Louis Children’s Hospital and Washington University. Canada and United States Seminars in Fetal and Neonatal MedicineSemin Fetal Neonatal Med 2025; DOI: 10.1016/j.siny.2025.101656 AbstractCongenital diaphragmatic hernia (CDH) is characterized by pulmonary hypoplasia. CDH lungs exhibit an inflammatory signature with impaired growth,

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A comparative analysis of clinical phenotypes and outcomes in childhood interstitial lung disease due to surfactant dysfunction disorders: focusing on mutations in SFTPC, ABCA3, and NKX2-1 genes

Xiaolei Tang1 , Shunying Zhao, Yuelin Shen1, Yu Tang, Xingfeng Yao, Hui Xu, Hui Liu, Xiaoyan Zhang, Xiao Li, Yanqiong Wang, Haiming YangBeijing Children’s Hospital, National Center for Children’s Health and Capital Medical University. Henan Children’s Hospital, Zhengzhou Children’s Hospital and Children’s Hospital Affiliated to Zhengzhou University. Children’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang

A comparative analysis of clinical phenotypes and outcomes in childhood interstitial lung disease due to surfactant dysfunction disorders: focusing on mutations in SFTPC, ABCA3, and NKX2-1 genes Read More »

Hypoxanthine Promotes Pulmonary Vascular Remodeling and Adenosine Deaminase Is a Therapeutic Target for Pulmonary Hypertension

Jun-Zhuo Shi, Yong-Jian Zhu, Meng-Jie Zhang, Yi Yan, Lu-Ling Zhao, Hong-Da Zhang, Yan Liu, Wen-Hui Wu, Zhe Cheng, Chun-Guang Qiu, Jie-Jian Kou, Yun-Feng Zhou, Xiao-Bin Pang, Ji-Wang Chen, Xin-Mei Xie, Yang-Yang He, Zhi-Cheng JingHuaihe Hospital and Henan University. First Affiliated Hospital of Zhengzhou University. Shanghai Children’s Medical Center, National Children’s Medical Center and Shanghai Jiao

Hypoxanthine Promotes Pulmonary Vascular Remodeling and Adenosine Deaminase Is a Therapeutic Target for Pulmonary Hypertension Read More »

Echocardiographic Assessment of Pulmonary Hemodynamics and Right Ventricular Performance in Neonatal Murine Hypoxia

Kel Vin Woo, Philip T. Levy, Carla J. Weinheimer, Amanda L. Hauck, Aaron Hamvas, David M. Ornitz, Attila Kovacs, Gautam K. SinghWashington University School of Medicine. Boston Children’s Hospital, Department of Pediatrics and Harvard Medical School. Ann and Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine. Children’s Hospital Michigan

Echocardiographic Assessment of Pulmonary Hemodynamics and Right Ventricular Performance in Neonatal Murine Hypoxia Read More »

Risk Factors and Predictors of Mechanical Ventilation in Neonates With Meconium Aspiration Syndrome: A Retrospective Study at King Salman Armed Forces Hospital, Tabuk, Saudi Arabia

Abdulaziz A. Bedaiwi, Muhanned Amawi, Wegdan MawlanaKing Salman Armed Forces Hospital.Saudi Arabia CureusCureus 2025; 17: DOI: 10.7759/cureus.88486 AbstractBackground: Meconium aspiration syndrome (MAS) is a critical neonatal condition predominantly associated with term and post-term pregnancies, characterized by the aspiration of meconium-stained amniotic fluid (MSAF) leading to severe respiratory distress. Despite advances in obstetric and neonatal care, MAS

Risk Factors and Predictors of Mechanical Ventilation in Neonates With Meconium Aspiration Syndrome: A Retrospective Study at King Salman Armed Forces Hospital, Tabuk, Saudi Arabia Read More »

Four decades of heart-lung transplantation: Milestones and outcomes in advanced cardiorespiratory failure

L. Lily Rosenthal, Anna Maria Mühlbauer, Carola Grinninger, Nikolaus A. Haas, Heinrich Netz, Robert Dalla Pozza, Jürgen Hörer, Sebastian Michel, R. Schramm, D. Graetz, Christian HaglLMU University Hospital Munich. Clinic Bogen. Heart and Diabetes Centre North Rhine-Westphalia. Clinic Gauting.Germany European Society of Cardiology Heart FailureESC Heart Fail 2025; DOI: 10.1002/ehf2.15411 AbstractAims: Heart-lung transplantation (HLTx) remains a life-saving intervention

Four decades of heart-lung transplantation: Milestones and outcomes in advanced cardiorespiratory failure Read More »

Revived role of reverse Potts shunt in management of paediatric severe pulmonary hypertension

Zhangwei Wang, Honghao Fu, Shoujun LiChinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovascular Diseases and Fuwai Hospital.China Cardiology in the YoungCardiol Young 2025; DOI: 10.1017/S1047951125101352 AbstractPulmonary artery hypertension in children is a progressive, fatal disease secondary to a variety of causes leading to right ventricular dysfunction. Traditional treatments include lung

Revived role of reverse Potts shunt in management of paediatric severe pulmonary hypertension Read More »

Tracheostomy and Chronic Ventilator Dependence After Congenital Diaphragmatic Hernia Repair: Long-Term Outcomes

Sarah D. King, Keerthi Burgi, Erin E. Perrone, George B. Mychaliska, Amy G. Filbrun, Joseph T. ChurchUniversity of Michigan and University of Michigan Medical School. United States Journal of Surgical ResearchJ Surg Res 2025; 314: 567-573DOI: 10.1016/j.jss.2025.07.052 AbstractIntroduction: There are limited data regarding long-term outcomes in patients with congenital diaphragmatic hernia (CDH) who require tracheostomy with chronic

Tracheostomy and Chronic Ventilator Dependence After Congenital Diaphragmatic Hernia Repair: Long-Term Outcomes Read More »

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