Fresh (PHresh). Less than 1-2 years since publication

Excessive Postnatal Smooth Muscle Differentiation in a Lung Specific Model of TBX4-related Pulmonary Hypertension

Lea C. Steffes, Kaylie A. Chiles, Sehar R. Masud, Aleen Rahman, Madeline Dawson, Csaba Galambos, Maya E. Kumar, Ripla AroraStanford University School of Medicine. Michigan State University. University of Colorado School of Medicine and Children’s Hospital Colorado.United States Journal of Clinical Investigation InsightsJCI Insights 2026; DOI: 10.1172/jci.insight.194251 AbstractHeterozygous TBX4 variants are the second most common genetic […]

Excessive Postnatal Smooth Muscle Differentiation in a Lung Specific Model of TBX4-related Pulmonary Hypertension Read More »

R213G-Mediated Redistribution of EC-SOD Protects Against Sugen-Hypoxia Pulmonary Hypertension in Mice

Daniel Colon Hidalgo, Caitlin V. Lewis, Thi‐Tina N. Nguyen, Janelle N. Posey, Samuel D. Burciaga, Nathan Dee, Christina Sul, Julie Harral, David Irwin, Cassidy Delaney, Eva S. NozikUniversity of Colorado Anschutz Medical Campus. United States Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70307 AbstractPulmonary hypertension (PH) is a progressive and life-threatening disease characterized by pulmonary vascular remodeling

R213G-Mediated Redistribution of EC-SOD Protects Against Sugen-Hypoxia Pulmonary Hypertension in Mice Read More »

Treprostinil Is Associated With Early and Sustained Improvement in Group 3 Pulmonary Hypertension and Right Ventricular Function in Children

Kaushik Parvathaneni, Justin J. Kochanski, Megha D. Tandel, Esther Liu, Alisa Arunamata, Jeffrey A. Feinstein, Rachel K. HopperStanford University School of Medicine and Stanford University.United States Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70304 AbstractUse of subcutaneous treprostinil (TRE) in children with pulmonary hypertension (PH) secondary to lung disease (group 3 PH) is not well described. We

Treprostinil Is Associated With Early and Sustained Improvement in Group 3 Pulmonary Hypertension and Right Ventricular Function in Children Read More »

Adapting the REVEAL Lite 2 score to the pediatric population through machine learning: insights from the REHIPED registry for pediatric pulmonary hypertension

Julia Playán-Escribano, Carlos Labrandero de Lera, Leticia Albert de la Torre,  Alejandro Rodríguez-Ogando, Antonio Moreno-Galdó, Inmaculada Guillén Rodríguez, Anna Sabaté-Rotés, Amparo Moya-Bonora, Lina María Caicedo Cuenca, María Jesús del Cerro, on behalf of the REHIPED investigatorsHospital General Universitario Gregorio Marañón. Hospital Universitario del Sureste, Arganda del Rey. Universidad Complutense de Madrid. Hospital Universitario La Paz. Hospital Universitario 12 de Octubre. Hospital General Universitario Gregorio Marañón. Hospital Universitari Vall d’Hebron, Vall d’Hebron Barcelona Hospital Campus,

Adapting the REVEAL Lite 2 score to the pediatric population through machine learning: insights from the REHIPED registry for pediatric pulmonary hypertension Read More »

Pulmonary arterial hypertension caused by compression of the left lower pulmonary vein in children

Li Chen, Cheng Wang, Jiachen Li, Lizhi Lv, Yongtao Wu, Gang Li, Guofeng Xing, Xiaoyong Jing, Zhimin Liu, Qiang WangBeijing Anzhen Hospital and Capital Medical University.  Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College. China Journal of Cardiothoracic SurgeryJ Cardiothorac Surg 2026; DOI: 10.1186/s13019-026-04085-x AbstractObjectives To investigate,

Pulmonary arterial hypertension caused by compression of the left lower pulmonary vein in children Read More »

Mid-term prognosis and risk stratification in patients with post-operative pulmonary hypertension: Insights from the Japanese Association of Congenital Heart Disease Registry (JACPHR)

Naofumi F. Sumitomo, Taku Ishii, Keiko Uchida, Susumu Hosokawa, Reina Ishizaki, Yoshiyuki Furutani, Hidekazu Ishida, Shinichi Takatsuki, Kei Inai, Shigetoyo Kogaki, Hiroyuki Fukushima, Yuichi Tamura, Hiroyuki Yamagishi, Shozaburo Doi, on behalf of The Japanese Association of Congenital Heart Disease Registry (JACPHR) membersKeio University School of Medicine. Institute of Science Tokyo. Tokyo Medical University. Japanese Red

Mid-term prognosis and risk stratification in patients with post-operative pulmonary hypertension: Insights from the Japanese Association of Congenital Heart Disease Registry (JACPHR) Read More »

Catheter and echocardiographic-focused management of primary pulmonary vein stenosis in premature infants: a single center 5-year experience

Keira Nassetta Conor P. O’Halloran, Emily Hoyt, Matthew Cornicelli, Nicolas Porta, Jeremy Fox, Alan W. Nugent, Paul Tannous, Amanda HauckAnn and Robert H. Lurie Children’s Hospital of Chicago.United States Journal of PerinatologyJ Perinatol 2026;DOI: 10.1038/s41372-026-02611-2 AbstractBackground/objectives: We describe the outcomes of pulmonary vein stenosis treatment in a cohort of premature infants using an assertive percutaneous management strategy

Catheter and echocardiographic-focused management of primary pulmonary vein stenosis in premature infants: a single center 5-year experience Read More »

Prognostic value of haemodynamic and neurophysiological assessments in newborns with hypoxic-ischaemic encephalopathy undergoing whole-body therapeutic hypothermia: a systematic review and meta-analysis of short-term outcomes

Mona Noureldein, Vincent So, Lamia Hayawi, Ayman Saker, Laurent Renesme, Anne Tsampalieros, Nadya Ben FadelBirmingham Heartlands Hospital and University Hospitals Birmingham NHS Foundation Trust. Children’s Hospital of Eastern Ontario. University of Ottawa.United Kingdom and Canada Archives of Disease in Childhood Fetal and Neonatal EditionArch Dis Child Fetal Neonatal Ed 2026; DOI: 10.1136/archdischild-2025-329322 AbstractObjective: To evaluate the prognostic

Prognostic value of haemodynamic and neurophysiological assessments in newborns with hypoxic-ischaemic encephalopathy undergoing whole-body therapeutic hypothermia: a systematic review and meta-analysis of short-term outcomes Read More »

[Association between adverse outcomes during hospitalization and early postnatal weight changes in term appropriate-for-gestational-age infants with early-onset sepsis]

Shi-Cheng Zeng, Xian-Lu Zhou, Ling-Ling Xiang, Zi-Yu HuaChildren’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, and Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory DiseasesChina Chinese Journal of Contemporary PediatricsZhongguo Dang Dai Er Ke Za Zhi 2026; 28:

[Association between adverse outcomes during hospitalization and early postnatal weight changes in term appropriate-for-gestational-age infants with early-onset sepsis] Read More »

Clinical profile, survival outcomes, and predictors of mortality in neonates with persistent pulmonary hypertension: a follow-up study from Hawassa, Ethiopia

Mohammed Nasir, Mihiretu AhmedHawassa University. Bushulo Mother to Child Center.Ethiopia BioMedical Central PediatricsBMC Pediatr 2026; DOI: 10.1186/s12887-026-06904-5 AbstractIntroduction: Persistent pulmonary hypertension of the newborn (PPHN) is a failure of normal fetal-to-neonatal circulatory transition. Evidence from low-resource settings remains limited. This study evaluated clinical characteristics, treatment outcomes, mortality predictors, and time to clinical and echocardiographic resolution among

Clinical profile, survival outcomes, and predictors of mortality in neonates with persistent pulmonary hypertension: a follow-up study from Hawassa, Ethiopia Read More »

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