Filed (PHiled). Greater than 1-2 years since publication

A hypothesis: Potential contributions of metals to the pathogenesis of pulmonary artery hypertension

C. Danielle Hopkins, Caitlin Wessel, Oscar Chen, Karim El-Hersh, Dakotah Cathey, Matthew C. Cave, Lu Cai, Jiapeng HuangUniversity of Louisville School of Medicine. University of Nebraska Medical Center. United States Life SciencesLife Sci 2023; DOI: 10.1016/j.lfs.2023.122289 AbstractPulmonary artery hypertension (PAH) as the group I of give pulmonary hypertension is characterized by vasoconstriction and vascular remodeling resulting […]

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A Review of Serotonin in the Developing Lung and Neonatal Pulmonary Hypertension

Jamie L. Archambault, Cassidy A. DelaneyUniversity of Colorado.United States BiomedicinesBiomedicines 2023; 11: DOI: 10.3390/biomedicines11113049 AbstractSerotonin (5-HT) is a bioamine that has been implicated in the pathogenesis of pulmonary hypertension (PH). The lung serves as an important site of 5-HT synthesis, uptake, and metabolism with signaling primarily regulated by tryptophan hydroxylase (TPH), the 5-HT transporter (SERT), and

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Reassessing the role of milrinone in the treatment of heart failure and pulmonary hypertension in neonates and children: a systematic review and meta-analysis

Felipe Yu Matsushita, Vera Lúcia Jornada Krebs, Carolina Vieira de Campos, Paula Vieira de Vincenzi Gaiolla, Werther Brunow de CarvalhoUniversity of São Paulo. Hospital Samaritano. Brazil European Journal of PediatricsEur J Pediatr 2023; DOI: 10.1007/s00431-023-05342-0 AbstractTo evaluate milrinone’s impact on pediatric cardiac function, focusing on its specific role as an inotrope and lusitrope, while considering its

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Unilateral Absent Pulmonary Artery in Pregnancy: A Case Report and Systematic Literature Review

Lauren Marie Kucirka, Shivani Desai, Barbara LeVarge, Jamie L. Conklin, M. Elisabeth Leong, Johanna Quist-Nelsonniversity of North Carolina at Chapel Hill School of Medicine.United States American Journal of PerinatologyAm J Perinatol 2023; DOI: 10.1055/a-2217-0241 AbstractObjective: Unilateral absence of a pulmonary artery (UAPA) is a rare congenital malformation associated with hemoptysis, pulmonary hypertension, and infection. Little is known about the impact on pregnancy

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Thrombotic Microangiopathy After Hematopoietic Stem Cell and Solid Organ Transplantation: A Review for Intensive Care Physicians

Sanober Nusrat, Hugh Davis, Kira MacDougall, James N. George, Ryotaro Nakamura, Azra BorogovacUniversity of Oklahoma Health Sciences Center. City of Hope. United States Journal of Intensive Care MedicineJ Intensive Care Med 2023; DOI: 10.1177/08850666231200193 AbstractIntensive care physicians may assume the primary care of patients with transplant-associated thrombotic microangiopathy (TA-TMA), an uncommon but potentially critical complication of

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Reduced FOXF1 links unrepaired DNA damage to pulmonary arterial hypertension

Sarasa Isobe, Ramesh V. Nair, Helen Y. Kang, Lingli Wang, Jan-Renier Moonen, Tsutomu Shinohara, Aiqin Cao1, Shalina Taylor, Shoichiro Otsuki, David P. Marciano, Rebecca L. Harper, Mir S. Adil, Chongyang Zhang, Mauro Lago-Docampo, Jakob Körbelin, Jesse M. Engreitz, Michael P. Snyder, Marlene RabinovitchLucile Packard Children’s Hospital and Stanford University School of Medicine. University Medical Center

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Right lower lung midline herniation as a rare complication in an infant with heart-lung transplantation: A case report

Dohyung Kim, Kwang Ho Choi, Hyungtae Kim, Jae Hong Lee, Younga Kim, Joung-Hee ByunPusan National University Yangsan Hospital and Pusan National University School of Medicine.Republic of Korea Pediatric TransplantationPediatr Transplant 2023; DOI: 10.1111/petr.14656 AbstractBackground: Lung herniation is a rare complication of heart-lung transplantation that can be fatal owing to vascular compromise and airway obstruction. To date, only

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Characterization of the congenital diaphragmatic hernia model in C57BL/6J fetal mice: a step toward lineage tracing experiments

Fabian Doktor, Rebeca Lopes Figueira Kasra Khalaj, Aizah Ijaz, Martin Lacher, Matisse Blundell, Lisa Antounians, Augusto ZaniThe Hospital for Sick Children and University of Toronto. University of Leipzig. Canada and Germany Pediatric Surgery InternationalPediatr Surg Int 2023; 39: DOI: 10.1007/s00383-023-05583-y AbstractPurpose: Lineage tracing is key to study the fate of individual cells and their progeny especially in

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Mitochondrial hyperfusion induces metabolic remodeling in lung endothelial cells by modifying the activities of electron transport chain complexes I and III

Manivannan Yegambaram, Xutong Sun, Qing Lu, Yan Jin, Wojciech Ornatowski, Jamie Soto, Saurabh Aggarwal, Ting Wang, Kim Tieu, Haiwei Gu, Jeffrey R. Fineman, Stephen M. BlackFlorida International University. University of Arizona. University of California San Francisco.United States Free Radical Biology and MedicineFree Radic Biol Med 2023; DOI: 10.1016/j.freeradbiomed.2023.11.008 AbstractObjective: Pulmonary hypertension (PH) is a progressive disease with

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Prostaglandin-E1 infusion in persistent pulmonary hypertension of the newborn

Stephanie M. Tsoi, Hythem Nawaytou, Hassan Almeneisi, Martina Steurer, Yili Zhao, Jeffrey R. Fineman, Roberta L. KellerUniversity of California San Francisco.United States Pediatric PulmonologyPediatr Pulmonol 2023; DOI: 10.1002/ppul.26759 AbstractBackground: Neonates with persistent pulmonary hypertension of the newborn (PPHN) can present with hypoxia and right ventricular dysfunction with resultant inadequate oxygen delivery and end-organ damage. This study describes

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