Filed (PHiled). Greater than 1-2 years since publication

Common Variation in EDN1 Regulatory Regions Highlights the Role of PPARγ as a Key Regulator of Endothelin in vitro

Mauro Lago-Docampo, Carlos Solarat, Luis Méndez-Martínez, Adolfo Baloira, Diana ValverdeUniversidade de Vigo. Galicia Sur Health Research Institute . Institute of Marine Research. Complexo Hospitalario Universitario de Pontevedra.Spain Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2022; 9: DOI: 10.3389/fcvm.2022.823133 AbstractPulmonary Arterial Hypertension (PAH) is a rare disease caused by the obliteration of the pulmonary arterioles, increasing pulmonary vascular resistance

Common Variation in EDN1 Regulatory Regions Highlights the Role of PPARγ as a Key Regulator of Endothelin in vitro Read More »

Thrombospondin-1 Plays a Major Pathogenic Role in Experimental and Human Bronchopulmonary Dysplasia

Brittany Ann Ruschkowski, Yousef Esmaeil, Kate Daniel, Chantel Gaudet, Behzad Yeganeh, David Grynspan, Robert P. JankovChildren’s Hospital of Eastern Ontario Research Institute. University of Ottawa.Canada American Journal of Respiratory and Critical Care MedicineAm J Respir Crit Care Med 2022; 205: 685-699DOI: 10.1164/rccm.202104-1021OC AbstractRationale: Extremely preterm infants develop bronchopulmonary dysplasia (BPD), a chronic lung injury that lacks effective

Thrombospondin-1 Plays a Major Pathogenic Role in Experimental and Human Bronchopulmonary Dysplasia Read More »

Effects of a Long-Term Wearable Activity Tracker-Based Exercise Intervention on Cardiac Morphology and Function of Patients with Cystic Fibrosis

Maria Anifanti, Stavros Giannakoulakos, Elpis Hatziagorou, Asterios Kampouras, John Tsanakas, Asterios Deligiannis, Evangelia KouidiAristotle University of Thessaloniki and Hippokration Hospital. Greece SensorsSensors 2022; 22: DOI: 10.3390/s22134884 AbstractSeveral studies have shown that patients with cystic fibrosis (CF), even at a young age, have pulmonary and cardiac abnormalities. The main complications are cardiac right ventricular (RV) systolic and/or

Effects of a Long-Term Wearable Activity Tracker-Based Exercise Intervention on Cardiac Morphology and Function of Patients with Cystic Fibrosis Read More »

Natural history of Myhre syndrome

David Dawei Yang, Marlene Rio, Caroline Michot, Nathalie Boddaert, Wael Yacoub, Nicolas Garcelon, Briac Thierry, Damien Bonnet, Sophie Rondeau, Dominique Herve, Stephanie Guey, Francois Angoulvant, Valerie Cormier‑DaireUniversité de Paris. Hôpital Universitaire Necker-Enfants Malades. INSERM U. Hôpital Lariboisière. France Orphanet Journal of Rare DiseasesOrphanet J Rare Dis 2022; 17: DOI: 10.1186/s13023-022-02447-x AbstractBackground: Myhre syndrome (MS) is a rare

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Risk Factors of Neonatal Acute Respiratory Distress Syndrome Based on the Montreux Definition in Neonates with Sepsis: A Retrospective Case-Control Study

Ya Hu, Kinhong Chen, Fang Wang, Chun Li, Weighong Yue, Hong WeiChildren’s Hospital of Chongqing Medical University. Ministry of Education Key Laboratory of Child Development and Disorders. National Clinical Research Center for Child Health and Disorders (Chongqing). China International Science and Technology Cooperation base of Child development and Critical Disorders. Chongqing Key Laboratory of Pediatrics.China

Risk Factors of Neonatal Acute Respiratory Distress Syndrome Based on the Montreux Definition in Neonates with Sepsis: A Retrospective Case-Control Study Read More »

Clinical characteristics and outcomes in neonates with perinatal acute respiratory distress syndrome in China: A national, multicentre, cross-sectional study

Long Chen, Jie Li, Yuan Shi, Chinese Neonatal ARDS (ChiNARDS) study groupChildren’s Hospital of Chongqing Medical University. The First Affiliated Hospital of Chongqing Medical University.China eClinicalMedicineeClinicalMedicine 2022; 55: DOI: 10.1016/j.eclinm.2022.101739 AbstractBackground: Neonatal acute respiratory distress syndrome (NARDS) was defined in 2017 and the epidemiological data remain unknown. Our objective was to explore aetiological factors, clinical characteristics and

Clinical characteristics and outcomes in neonates with perinatal acute respiratory distress syndrome in China: A national, multicentre, cross-sectional study Read More »

Lung transplantation with concomitant cardiac repair for congenital hypoplasia of bilateral pulmonary arteries and patent ductus arteriosus

Che‑Chih Cheng, Ming‑Tai Lin, Shu‑Chien Huang, Hsao‑Hsun HsuKaohsiung Armed Forces General Hospital. National Taiwan University Hospital and National Taiwan University College of Medicine.Taiwan Journal of Cardiothoracic SurgeryJ Cardiothorac Surg 2022; 17: DOI: 10.1186/s13019-022-01792-z AbstractBackground: Profound pulmonary arterial hypertension with end-stage right heart failure is considered to be the main cause of death in children with un-repaired congenital

Lung transplantation with concomitant cardiac repair for congenital hypoplasia of bilateral pulmonary arteries and patent ductus arteriosus Read More »

Innovative Fetal Therapy for a Giant Congenital Pulmonary Airway Malformation with Hydrops

Denise B. Klinkner, Thomas Atwell, Ayssa Teles Abrao Trad, Matthew R. Callstrom, Mohamed Yasir Qureshi, Ellen Bendel Stenzel, Mauro Schenone, Rodrigo RuanoMayo Clinic. University of Miami.United States Fetal Diagnosis and TherapyFetal Diagn Ther 2022; 49: 250-255DOI: 10.1159/000521690 AbstractIntroduction: Congenital pulmonary airway malformations (CPAMs) complicated by hydrops portend significant morbidity and mortality, with fetal survival estimates less than

Innovative Fetal Therapy for a Giant Congenital Pulmonary Airway Malformation with Hydrops Read More »

A Protocol for Fabrication and on-Chip Cell Culture to Recreate PAH-Afflicted Pulmonary Artery on a Microfluidic Device

Tanoy Sarkar, Trieu Nguyen, Sakib M. Moinuddin, Kurt R. Stenmark, Dipongkor Saha, Fakhrul AhsanCalifornia Northstate University College of Pharmacy. University of Colorado Denver, Anschutz Medical Campus. MedLuidics.United States MicromachinesMicromachines 2022; 13: DOI: 10.3390/mi13091483 AbstractPulmonary arterial hypertension (PAH) is a rare pulmonary vascular disease that affects people of all ethnic origins and age groups including newborns. In

A Protocol for Fabrication and on-Chip Cell Culture to Recreate PAH-Afflicted Pulmonary Artery on a Microfluidic Device Read More »

Pilot study for comparative assessment of dual-energy computed tomography and single-photon emission computed tomography V/Q scanning for lung perfusion evaluation in infants

Karen I. Ramirez-Suarez, Christian A. Barrera, Hansel J. Otero, David M. Biko, Lisa J. States, Sabah Servaes, Xiaowei Zhu, James C. Davis, Josrph Piccione, Jordan B. RappChildren’s Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine. West Virginia University Medicine Children’s Hospital.United States Pediatric PulmonologyPediatr Pulmonol 2022; 57: 702-710DOI: 10.1002/ppul.25788 AbstractObjective: To evaluate clinical applications

Pilot study for comparative assessment of dual-energy computed tomography and single-photon emission computed tomography V/Q scanning for lung perfusion evaluation in infants Read More »

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