Filed (PHiled). Greater than 1-2 years since publication

Inflammatory processes may predispose children to high-altitude pulmonary edema

Anthony G. Durmowicz, Edward Nordeweir, Richard Nicholas, John T. ReevesUniversity of Colorado Health Sciences Center.United States Journal of PediatricsJ Pediatr 1997; 130: 838-480DOI: 10.1016/s0022-3476(97)80033-9 AbstractWe investigated retrospectively whether the preexistence of inflammation-producing illnesses such as viral respiratory tract infections contributed to the development of high-attitude pulmonary edema in children. We found that the large majority of […]

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Viral respiratory infection increases susceptibility of young rats to hypoxia-induced pulmonary edema

Todd C. Carpenter, John T. Reeves, Anthony G. DurmowitzUniversity of Colorado Health Sciences Center.United States Journal of Applied PhysiologyJ Appl Physiol 1998; 84: 1048-1054 DOI: 10.1152/jappl.1998.84.3.1048 AbstractRecent clinical observations of a high incidence of preexisting respiratory infections in pediatric cases of high-altitude pulmonary edema prompted us to ask whether such infections would increase the susceptibility to hypoxia-induced

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Pulmonary edema in 6 children with Down syndrome during travel to moderate altitudes

Anthony G. DurmowiczUniversity of Utah Health Science Center and Primary Children’s Medical Center.United States PediatricsPediatrics 2001; 108: 443-447DOI: 10.1542/peds.108.2.443 AbstractObjective: Children with Down syndrome (DS) are living longer and are increasingly participating in recreational activities. When a child with DS was diagnosed with high-altitude pulmonary edema (HAPE), this study was undertaken to determine whether and under what

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High-altitude pulmonary edema in children with underlying cardiopulmonary disorders and pulmonary hypertension living at altitude

Bibhuti B. Das, Robert R. Wolfe, Kak-Chen Chan, Gary L. Larsen, John T. Reeves, Dunbar IvyChildren’s Hospital, Denver.United States Archives of Pediatric and Adolescent MedicineArch Pediatr Adolesc Med 2004; 158: 1170-1176DOI: 10.1001/archpedi.158.12.1170 AbstractBackground: Pulmonary hypertension has not been described as a predisposing risk factor for high-altitude pulmonary edema (HAPE) in children. Previous studies have shown an association

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Effects of altitude and exercise on pulmonary capillary integrity: evidence for subclinical high-altitude pulmonary edema

Marlowe W. Eldridge, Ruedi K. Braun, Ken Y. Yoneda, William F. WalbyUniversity of Wisconsin.United States Journal of Applied PhysiologyJ Appl Physiol 2006; 100: 972-980 DOI: 10.1152/japplphysiol.01048.2005 AbstractStrenuous exercise may be a significant contributing factor for development of high-altitude pulmonary edema, particularly at low or moderate altitudes. Thus we investigated the effects of heavy cycle ergometer exercise (90%

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Interventions for preventing high altitude illness: Part 2. Less commonly-used drugs

Alejandro G Gonzalez Garay, Daniel Molano Franco, Víctor H Nieto Estrada, Arturo J Martí-Carvajal, Ingrid Arevalo-RodriguezNational Institute of Pediatrics.Mexico Cochrane Database of Systemic ReviewsCochrane Database Syst Rev 2018; 3: DOI: 10.1002/14651858.CD012983 AbstractBackground: High altitude illness (HAI) is a term used to describe a group of mainly cerebral and pulmonary syndromes that can occur during travel to elevations

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Pulmonary hemodynamics in children living at high altitudes

Dante Penaloza, Francisco Sime, Luis RuizUniversity Cayetano Heredia.Peru High Altitude Medicine and BiologyHigh Altit Med Biol 2008; 9: 199-207DOI: 10.1089/ham.2008.1004 AbstractThere are numerous publications on altitude-related diseases in adults. In addition, an International Consensus Statement published in 2001 deals with altitude-related illnesses occurring in lowland children who travel to high altitudes. However, despite the millions of

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Child health and living at high altitude

Susan Niermeyer, P. Andrade Mollinedo, L. HuichoUniversity of Colorado School of Medicine and Children’s Hospital of Colorado. Caja Nacional de Salud and Clínica del Sur and Clínica Alemana. Universidad Nacional Mayor de San Marcos and Universidad Peruana Cayetano Heredia.United States, Bolivia and Peru Archives of Disease in ChildrenArch Dis Child 2009; 94: 806-811DOI: 10.1136/adc.2008.141838 AbstractThe health of

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Clinical manifestations and long-term follow-up in pediatric patients living at altitude with isolated pulmonary artery of ductal origin

Shinichi Takatsuki, Jeffrey Darst, Bibhuti B. Das, Thomas E. Fagan, Robert Wolfe, David Dunbar IvyChildren’s Hospital Colorado and University of Colorado Denver.United States Pediatric CardiologyPediatr Cardiol 2012; 33: 775-781DOI: 10.1007/s00246-012-0213-z AbstractThis study’s aim was to define the clinical manifestations and long-term outcome of pediatric patients living at altitude with isolated pulmonary artery (PA) of ductal origin

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Increased hepcidin levels in high-altitude pulmonary edema

Sandro Altamura, Peter Bärtsch, Christoph Dehnert, Marco Maggiorini, Günter Weiss, Igor Theurl, Martina U. Muckenthaler, Heimo MairbäurlUniversity Hospital Heidelberg. University Hospital Zürich. Medical University of Innsbruck. Germany, Switzerland and Austria Journal of Applied PhysiologyJ App Physiol 2015; 118: 292-298 DOI: 10.1152/japplphysiol.00940.2014 AbstractLow iron availability enhances hypoxic pulmonary vasoconstriction (HPV). Considering that reduced serum iron is caused

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