Diagnostic Testing for Pulmonary Vascular Disease. Invasive Testing

Doppler Echocardiographic Features of Pulmonary Vein Stenosis in Ex-Preterm Children

Yalin Lin, Alena K. Amin, Roberta L. Keller, David F. Teitel, Hythem M. NawaytouUniversity of California, San Francisco.United States Journal of the American Society of EchocardiographyJ Am Soc Echocardiogr 2022; 35: 435-442DOI: 10.1016/j.echo.2021.12.015 AbstractBackground: Echocardiography is used to screen for the presence of pulmonary vein stenosis (PVS) in ex-preterm infants and children. However, there are no standard […]

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Outpatient prescription of pulmonary vasodilator therapy to preterm children with bronchopulmonary dysplasia

Ida Jeremiasen, Karin Tran-Lundmark, Mikaela Dolk, Estelle NaumburgLund University and Skåne University Hospital. Umeå University.Sweden Acta PaediatricaActa Paediatr 2023; 112: 409-416DOI: 10.1111/apa.16615 Abstract Aim: The use of pulmonary vasodilator therapy in children born preterm is largely unknown. Our aim was to map prescription patterns in children with bronchopulmonary dysplasia in Sweden.Methods: This was a descriptive national registry-based study

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Hemodynamic Characterization of Neonates With Congenital Diaphragmatic Hernia-Associated Pulmonary Hypertension by Cardiac Catheterization

Paula Dias Maia, Jason Gien, John P. Kinsella, Jenny Zablah, Gareth Morgan, D. Dunbar Ivy, Steven H. Abman, Benjamin S. FrankUniversity of Colorado School of Medicine.United States Journal of PediatricsJ Pediatr 2022; DOI: 10.1016/j.jpeds.2022.11.028 AbstractWe examined the results of cardiac catheterization in infants with congenital diaphragmatic hernia (CDH) from 2009 to 2020. Catheterization confirmed pulmonary arterial

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Multimodality Deep Phenotyping Methods to Assess Mechanisms of Poor Right Ventricular-Pulmonary Artery Coupling

Farhan Raza, Callyn Kozitza, Chris Lechuga, Daniel Seiter, Philip Corrado, Mohammed Merchant, Naga Dharmavaram, Claudia Korcarz, Marlowe Eldridge, Christopher Francois, Oliver Wieben, Naomi CheslerUniversity of Wisconsin, Madison. University of California, Irvine. Mayo Clinic. United States FunctionFunction 2022; 3: DOI: 10.1093/function/zqac022 AbstractDeep phenotyping of pulmonary hypertension (PH) with multimodal diagnostic exercise interventions can lead to early focused

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A novel non-invasive and echocardiography-derived method for quantification of right ventricular pressure-volume loops

Manuel J. Richter, Athiththan Yogeswaran, Faeq Husain-Sved, Istvan Vadasc, Zvomimir Rako, Emad Mojajerani, Hossein A. Ghofrani, Robert Naeije, Werner Seeger, Ulrike Herberg, Andreas Rieth, Ryan J. Tedford, Friedrich Grimminger, Henning Gall, Khodr TelloJustus-Liebig-University Giessen. Kerckhoff Heart, Rheuma and Thoracic Center. Imperial College London. Erasme University Hospital. University of Bonn. Medical University of South Carolina. Germany,

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Acute Pulmonary Vasodilator Testing and Long-Term Clinical Course in Segmental Pulmonary Vascular Disease

Liezl Domingo, H. Sonali Magdo, Ronald W. DayUniversity of Utah and Primary Children’s Hospital.United States Pediatric CardiologyPediatr Cardiol 2018; 39: 501-508DOI: 10.1007/s00246-017-1780-9 AbstractResults of acute pulmonary vasodilator testing (AVT) and the outcome of medical therapy have not been described in patients with segmental pulmonary vascular disease (SPVD). We sought to compare the pulmonary vasodilatory effects of

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Acute vasodilator testing: An opportunity to advance the precision care of pulmonary hypertension

Meghan M. Cirulis, Lynda O. Jorgensen, Ronald W. DayUniversity of Utah and Primary Children’s Hospital.United States Respiratory Medicine Case ReportsRespir Med Case Rep 2019; 28: DOI: 10.1016/j.rmcr.2019.100911 AbstractThe pulmonary arterial pressure of a child with severe pulmonary arterial hypertension immediately normalized while breathing nitric oxide during heart catheterization at 8 years of age. Her acute pulmonary

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Pulmonary artery acceleration time in young children is determined by heart rate and transpulmonary gradient but not by pulmonary blood flow: A simultaneous echocardiography-cardiac catheterization study

Christiana Tai, Anyir Hsieh, Anita J. Moon-Grady, Roberta L. Keller, David Teitel, Hythem M. NawaytouUniversity of California, San FranciscoUnited States EchocardiographyEchocardiography 2022; 39: 895-905DOI: 10.1111/echo.15397 AbstractIntroduction: Pulmonary artery acceleration time (PAAT) is considered useful for the non-invasive evaluation of pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR). PAAT is dependent on PAP, PVR, pulmonary artery compliance,

Pulmonary artery acceleration time in young children is determined by heart rate and transpulmonary gradient but not by pulmonary blood flow: A simultaneous echocardiography-cardiac catheterization study Read More »

Distinguishing exercise intolerance in early-stage pulmonary hypertension with invasive exercise hemodynamics: Rest VE /VCO2 and ETCO2 identify pulmonary vascular disease

Farhan Raza, Naga Dharmavaram MD, Timothy Hess, Ravi Dhingra, James Runo, Amy Chybowski, Callyn Kozitza, Supria Batra, Evelyn M. Horn, Naomi Chesler, Marlowe EldridgeUniversity of Wisconsin-Madison. Weill Cornell Medicine. University of California-Irvine.United States Clinical CardiologyClin Cardiol 2022; 45: 742-751DOI: 10.1002/clc.23831 AbstractBackground: Among subjects with exercise intolerance and suspected early-stage pulmonary hypertension (PH), early identification of pulmonary vascular

Distinguishing exercise intolerance in early-stage pulmonary hypertension with invasive exercise hemodynamics: Rest VE /VCO2 and ETCO2 identify pulmonary vascular disease Read More »

Non-Invasive Cardiac Output Determination Using Magnetic Resonance Imaging and Thermodilution in Pulmonary Hypertension

Lindsey A. Crowe, Léon Genecand, Anne-Lise Hachulla, Stéphane Noble, Maurice Beghetti, Jean-Paul Vallée, Frédéric LadorUniversity of Geneva and Geneva University Hospitals. Centre Universitaire Romand de Cardiologie et Chirurgie Cardiaque Pédiatrique and University of Geneva and Lausanne.Switzerland Journal of Clinical MedicineJ Clin Med 2022; 11: DOI: 10.3390/jcm11102717 AbstractMagnetic resonance imaging (MRI) can be used to measure cardiac

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