Class 5. Pulmonary Hypertension Associated with Hematological, Systemic, Metabolic, Nutritional and Other Disorders

The Epidemiology of Pulmonary Hypertension in Sub-Saharan Africa-A Systematic Report

Katarina Zeder, Lanjing Wang, Veranyuy Ngah, Armella Santi, Eric W. Robbins, Ana O. Mocumbi, Judith Namuyonga, Peter Nyasulu, Gabor Kovacs, Marc Humbert, Geoff Strange, Simon Stewart, Guoqing Diao, Bradley A. MaronUniversity of Maryland. Medical University of Graz. George Washington University. Stellenbosch University. University Eduardo Mondlane. Uganda Heart Institute and Makerere University College of Health Sciences. […]

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Etiologies of Pulmonary Arterial Hypertension in Early Infants: A 4-year Experience from a Tertiary Care Center in Southern India

Ysphaneendra Mallimoggala, Monalisa Biswas, Nitin Thyagaraja, H. Koushik, Krishnananda Nayak, Shrikiran Aroor, Varashree Bolar Suryakanth, Leslie LewisKasturba Medical College of Manipal Academy of Higher Education, Manipal College of Health Professionals and National Institute of Mental Health and Neuro Sciences. India Annals of African MedicineAnn Afr Med 2026; DOI: 10.4103/aam.aam_555_26 AbstractIntroduction: Pulmonary arterial hypertension (PAH) is relatively uncommon

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Pulmonary Hypertension with a High-Output Hemodynamic Profile in a Child with MELAS: A Case Report

Miki Kanai, Hirofumi Tsuru, Takanori Onuki, Shunsuke Nukaga, Shigehito Baba, Masanori Tsukada, Tadaaki Abe, Fujito Numano, Kei Murayama, Akihiko SaitohSaiseikai Niigata Kenoh Kikan Hospital. Niigata University School of Medicine. Juntendo University. Japan Internal MedicineIntern Med 2026; DOI: 10.2169/internalmedicine.7614-26 AbstractPulmonary hypertension (PH) is uncommon in myopathy, encephalopathy, lactic acidosis, and stroke-like (MELAS) and its hemodynamics are poorly

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Identification of Clinical Sub-Phenotypes of Sickle Cell Disease Using Latent Class Analysis

Shaina M. Willen, Ann M. Brunson, Oyebimpe O. Adesina, Ted WunUniversity of California Davis. United States American Journal of HematologyAm J Hematol 2026; DOI: 10.1002/ajh.70459 AbstractSickle cell disease (SCD), a monogenic disorder, exhibits variable severity due to genetic and environmental modifiers. Prior studies have proposed hemolytic and vaso-occlusive sub-phenotypes based on limited data. We used latent

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Cardiac Remodeling Patterns in Pediatric and Adolescent Patients with Sickle Cell Disease and Their Association with the Genotype and Clinical Severity of the Disease: A Systematic Review

Alam Eldin M. Mustafa, Niemat Mohammed Tahir AliKing Khalid University. University of Kordofan.Saudi Arabia and Sudan HealthcareHealthcare 2026; 14:DOI: 10.3390/healthcare14142180 AbstractBackground: Sickle cell disease (SCD) is the most common inherited blood disorder globally, affecting approximately 300,000 newborns annually. Cardiac remodeling, resulting from chronic anemia, vascular obstruction, and endothelial dysfunction, substantially contributes to morbidity and mortality in patients

Cardiac Remodeling Patterns in Pediatric and Adolescent Patients with Sickle Cell Disease and Their Association with the Genotype and Clinical Severity of the Disease: A Systematic Review Read More »

Long-Term Complications of Sickle Cell Disease

Luisanna M. Sánchez, Ajibike Lapite, Alicia Chang, Titilope A. FasipeIndiana Hemophilia and Thrombosis Center. Baylor College of Medicine and exas Children’s Hospital. University of Texas at Austin and Dell Children’s Hospital. United States Pediatrics in ReviewPediatr Rev 2026; 47: 394-403DOI: 10.1542/pir.2024-006446 AbstractSCD is a prevalent genetic disorder marked by chronic complications that impact quality of life

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Disease-related complications and risk factors in hemoglobin H disease in a Thai multicenter registry

Nattiya Teawtrakul, Duantida Songdej, Chattree Hantaweepant, Adisak Tantiworawit, Sasinee Hantrakool, Pornpun Sripornsawan, Pacharapan Surapolchai, Supanun Lauhasurayotin, Kitti Torcharus, Pranee Sutcharitchan, Noppacharn Uaprasert, Krissana Panrong, Napat Laoaroon, Patcharee Komvilaisak, Panachai Silpsamrit, Arunotai Meekaewkunchorn, Bunchoo Pongtanakul, Pimlak Charoenkwan & Red Blood Cell Disorders Study GroupSrinagarind Hospital and Khon Kaen University. Ramathibodi Hospital, Siriraj Hospital and Mahidol University.

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A Life Without Lemons: A Case of Severe Pulmonary Arterial Hypertension Secondary to Vitamin C Deficiency in a Child With Autism Spectrum Disorder

Beau Redwood, Simon Erickson, Lily Loughman, Zoe VettenPerth Children’s Hospital. Genetic Services of Western Australia.Australia Journal of Pediatrics and Child HealthJ Pediatr Child Health 2026; DOI: 10.1111/jpc.70448 AbstractAbstract Not Available CategoryClass V. Pulmonary Hypertension Associated with Hematological, Systemic, Metabolic, Nutritional and Other DisordersMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Disease Fresh

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Sickle cell disease-associated pulmonary hypertension: an integrated framework linking pathologies, mechanisms, and clinical phenotypes

Florence Vallelian, Dominik J. Schaer, Benoit Lechartier, Paul W. Buehler, David C. IrwinUniversity of Zurich. Lausanne University Hospital and University of Lausanne. University of Maryland. Anschutz Medical Campus School of Medicine and University of Colorado. Switzerland and United States eBioMedicineeBioMedicine 2026; DOI: 10.1016/j.ebiom.2026.106288 AbstractSickle cell disease-associated pulmonary hypertension (SCD-PH) affects approximately 10% of adults with SCD

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Prevalence and Risk Factors for Pulmonary Hypertension in Children with Sickle Cell Disease: A Prospective Observational Study from Central India

Kapil Dev Rabha, Rajkumar Kundavaram, Pooja Soni, Amber Kumar, NarendraKumar Chaudhary, Bhavna DhingraLower Assam Hospital and Research Centre. All India Institute of Medical Sciences.India Indian Journal of PediatricsInd J Pediatr 2026; DOI: 10.1007/s12098-026-06175-z AbstractAbstract Not Available CategoryClass V. Pulmonary Hypertension Associated with Hematological, Systemic, Metabolic, Nutritional and Other Disorders Age Focus: Pediatric Pulmonary Vascular Disease Fresh

Prevalence and Risk Factors for Pulmonary Hypertension in Children with Sickle Cell Disease: A Prospective Observational Study from Central India Read More »

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