Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

A machine learning approach to predict mortality and neonatal persistent pulmonary hypertension in newborns with congenital diaphragmatic hernia. A retrospective observational cohort study

Luana Conte, Ilaria Amodeo, Giorgio De Nunzio, Genny Rafaeli, Irene Borzani, Nicola Persico, Alice Griggio, Giuseppe Como, Mariarosa Colnaghi, Monica Fumagalli, Donato Cascio, Giacomo CavallaroUniversità Degli Studi Di Palermo. Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico. Laboratory of Interdisciplinary Research Applied to Medicine (DReAM). “E. De Giorgi”, University of Salento. Università Degli Studi Di Milano. […]

A machine learning approach to predict mortality and neonatal persistent pulmonary hypertension in newborns with congenital diaphragmatic hernia. A retrospective observational cohort study Read More »

Prevalence and outcomes of air leak syndrome and subtypes in neonates in the United States

Adam Beaton, Prithvi Sendi, Paul A. Martinez, Balagangadhar R. TotapallyCohen Children’s Medical Center. Nicklaus Children’s Hospital. Florida International University. United States Journal of Neonatal-Perinatal MedicineJ Neonatal Perinatal Med 2025; 17: 846-857DOI: 10.1177/19345798241308491 AbstractObjectives: To describe the prevalence, risk factors, and outcomes for neonatal air leak syndrome and its subtypes (pneumothorax, pneumomediastinum, pneumopericardium, pulmonary interstitial emphysema, and pneumoperitoneum), evaluate variables associated with the development

Prevalence and outcomes of air leak syndrome and subtypes in neonates in the United States Read More »

Fetoscopic Endoluminal Tracheal Occlusion-Synergic Therapies in the Prenatal Treatment of Congenital Diaphragmatic Hernia

Zsolt Bara, Horea Gozar, Nándor Nagy, Simona Gurzu, Zoltán Derzsi, Timea Forró, Evelyn Kovács, Ioan JungGeorge Emil Palade University of Medicine, Pharmacy, Science and Technology of Targu Mures. County Emergency Clinical Hospital. Semmelweis University. Romanian Academy of Medical Sciences.Romania and Hungary International Journal of Molecular SciencesInt J Mol Sci 2025; 26: DOI: 10.3390/ijms26041639 AbstractCongenital diaphragmatic hernia

Fetoscopic Endoluminal Tracheal Occlusion-Synergic Therapies in the Prenatal Treatment of Congenital Diaphragmatic Hernia Read More »

Growing Up with Developmental Lung Diseases: A Review for the Adult Pulmonologist

Yadira Rivera-Sanchez, Zachary W. Blair, Tyler J. Wall, Kara N. GossUniversity of Texas Southwestern Medical Center.United States ChestChest 2025; DOI: 10.1016/j.chest.2025.02.014 AbstractTopic importance: Improved childhood management strategies have decreased the early life morbidity and mortality of severe developmental lung disorders, such that an increasing number of individuals ultimately transition care to adult pulmonologists for management. Alternatively, individuals

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Are Early, Frequent Echocardiograms Necessary to Improve Outcomes of Neonates with Congenital Diaphragmatic Hernia?

Michelle J. Yang, Ryan J. Carpenter, Katie W. Russell, Stephen J. Fenton, Christian C. Yost, Bradley A. YoderUniversity of Utah School of Medicine and Primary Children’s Hospital.United States Journal of PediatricsJ Pediatr 2025; DOI: 10.1016/j.jpeds.2025.114510 AbstractObjective: To determine if timing of first postnatal echocardiogram (ECHO), early vs delayed, affects the use of extracorporeal membrane oxygenation (ECMO) and

Are Early, Frequent Echocardiograms Necessary to Improve Outcomes of Neonates with Congenital Diaphragmatic Hernia? Read More »

Bosentan as adjunctive therapy in neonates with congenital diaphragmatic hernia-associated pulmonary hypertension: a case series

Aster De Vadder, Lotte Lemloh, Bartolomeo Bo, Lennart Hale, Neil Patel, Andreas Mueller, Florian KipfmuellerChildren’s Hospital, University of Bonn. Royal Hospital for Children. Germany and United Kingdom European Journal of PediatricsEur J Pediatr 2025; 184: DOI: 10.1007/s00431-025-06019-6 AbstractCongenital diaphragmatic hernia (CDH)-associated pulmonary hypertension (PH) is associated with high morbidity and mortality. Pulmonary vasodilative management is challenging

Bosentan as adjunctive therapy in neonates with congenital diaphragmatic hernia-associated pulmonary hypertension: a case series Read More »

Severe pulmonary hypertension in a small-for-date neonate with skeletal dysplasia

Khuloud Mohamed, Mohammad A. A. Bayoumi, Muhammed Riyas Rahmath, Einas Elzubier ElmalikHamad Medical CorporationQatar British Medical Journals Case ReportsBMJ Case Rep 2025; 18: DOI: 10.1136/bcr-2024-264256 AbstractAbstract Not Available CategoryClass III. Pulmonary Hypertension Associated with Lung Hypoplasia Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication Article Access

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Infants With a Congenital Diaphragmatic Hernia Had Favourable Pulmonary Hypertension Outcomes at 1 Year of Age

Alice Dirick, Marilyne Levy, Kelly Mellul, Maxime Coignard, Naziha Khen-Dunlop, Alexandre Lapillonne Julien Stirnemann, Elsa Kermorvant-DucheminNecker-Enfants Malades Hospital. France Acta PediatricaActa Pediatr 2025; DOI: 10.1111/apa.70019 AbstractAim: Pulmonary hypertension is frequent in neonates with a congenital diaphragmatic hernia, but long-term data have been scarce. Our aim was to examine its prevalence, evolution and management and identify factors associated

Infants With a Congenital Diaphragmatic Hernia Had Favourable Pulmonary Hypertension Outcomes at 1 Year of Age Read More »

Case Report: Respiratory outcome in a preterm infant following previable rupture of membranes and persistent oligohydramnios

Akila Subramanian, Ong Kai Zhi, Arun Kumar Pugalenthi, Victor Samuel Rajadurai, Lay Kok Tan, Suresh ChandranKK Women’s and Children’s Hospital. Lee Kong Chian School of Medicine. Duke-NUS Medical School. Yong Loo Lin School of Medicine.Singapore Frontiers in PediatricsFront Pediatr 2025; 12: DOI: 10.3389/fped.2024.1457129 AbstractMid-trimester preterm premature rupture of membranes is a rare complication of pregnancy associated

Case Report: Respiratory outcome in a preterm infant following previable rupture of membranes and persistent oligohydramnios Read More »

Pulmonary Morbidity in Congenital Diaphragmatic Hernia Survivors Treated at a Non-ECMO Center From 1998 to 2015: A Cross-Sectional Study

Ulla Lei Larsen, Lone Agertoft, Anne Maria Herskind, Thomas Strøm, Palle Toft, Susanne HalkenOdense University Hospital. University of Southern Denmark. H.C. Andersen Children’s Hospital. Hospital Sønderjylland.Denmark Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.27468 AbstractIntroduction: A main feature of CDH is lung hypoplasia and the related presentation of pulmonary hypertension and cardiac dysfunction. Multiple factors influence pulmonary status

Pulmonary Morbidity in Congenital Diaphragmatic Hernia Survivors Treated at a Non-ECMO Center From 1998 to 2015: A Cross-Sectional Study Read More »

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