Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

Hidden cardiovascular morbidity in children and young adults born with congenital diaphragmatic hernia: A population-based study

Katarina Övermo Tydén, Felicia Nordenstam, Björn Frenckner, Carmen Mesas BurgosKarolinska University Hospital. Sweden Journal of Pediatric SurgeryJ Pediatr Surg 2022; 57: 510-515DOI: 10.1016/j.jpedsurg.2022.03.028 AbstractIntroduction: Congenital diaphragmatic (CDH) hernia is a rare congenital malformation with considerable mortality and morbidity in the neonatal period. The majority of the children today survive but little is known about long term cardiovascular […]

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Oxygen Saturation Index in Neonates with a Congenital Diaphragmatic Hernia: A Retrospective Cohort Study

Emily J. J. Horn-Oudshoorn, Marijn J. Vermeulen, Kelly J. Crossley, Suzan C. M. Cochius-den Otter, J. Marco Schnater, Irwin K.M. Reiss, Philip L. J. DeKoninckErasmus MC University Medical Center, Rotterdam. Monash University. Netherlands and Australia NeonatologyNeonatology 2022; 119: 111-118DOI: 10.1159/000520883 AbstractIntroduction: The oxygenation index (OI) is a marker for respiratory disease severity and adverse neonatal outcomes. The

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High altitude simulation testing in patients with congenital diaphragmatic hernia

Ashlyn E. Whitlock, Catherine A. Sheils, Jill M. Zalieckas, Gary Visner, Mary Mullen, Mollie Studley, Lindsay Lemire, Terry L. BuchmillerBoston Children’s Hospital and Harvard Medical School.United States Journal of Pediatric SurgeryJ Pediatr Surg 2022; 57: 195-198DOI: 10.1016/j.jpedsurg.2021.10.044 AbstractAim of study: Congenital Diaphragmatic Hernia (CDH) is associated with lung hypoplasia and pulmonary hypertension. Many patients receive care in

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Predicting treatment of pulmonary hypertension at discharge in infants with congenital diaphragmatic hernia

Burhan Mahmood, Karna Murthy, Natalie Rintoul, Mark Weems, Sarah Keene, Beverly Brozanski, Robert DiGeronimo, Beth Haberman, Holly Hedrick, Jason Gien, Ruth Seabrook, Noorjahan Ali, Rachel Chapman, John Daniel, Allen Harrison, Yvette Johnson, Nicolas F. M. Porta, Michael Uhing, Isabella Zaniletti, Theresa R. GroverChildren’s Hospitals Neonatal ConsortiumUnited States Journal of PerinatologyJ Perinatol 2022; 42: 45-52DOI: 10.1038/s41372-021-01249-6 AbstractObjective: To

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Upregulated TSP1 and CD47 Expression in the Lung in Nitrofen-induced Congenital Diaphragmatic Hernia

Hajime TakayasuKitasato University. University of Tsukuba.Japan Pediatrics InternationalPediatr Int 2022; DOI: 10.1111/ped.15447 AbstractBackground: Persistent pulmonary hypertension remains a major cause of mortality and morbidity in congenital diaphragmatic hernia (CDH). The secreted glycoprotein thrombospondin-1 (TSP1), a ligand for receptor CD47, is widely expressed on both systemic and pulmonary vascular cells. TSP1-CD47 signaling has been reported to be one

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Echocardiographic Assessment of Pulmonary Hypertension in Neonates with Congenital Diaphragmatic Hernia Using Pulmonary Artery Flow Characteristics

Florian Kipfmueller, Lukas Schroeder, Ulrich Gembruch, Suemeyra Akkas, Flaminia Pugnaloni, Bartolomeo Bo, Lotte Lemloh, Annegret Geipel, Christoph Berg, Andreas Heydweiller, Andreas MuellerUniversity of Bonn. Ospidale Bambinu Gesu. University Hospital Cologne.Germany and Italy Journal of Clinical MedicineJ Clin Med 2022; 11: DOI: 10.3390/jcm11113038 AbstractBackground: Assessment of pulmonary hypertension (PH) is essential in neonates with congenital diaphragmatic hernia

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Fetal endoscopic tracheal occlusion and pulmonary hypertension in moderate congenital diaphragmatic hernia

Roopali Donepudi, Michael A. Belfort, Alireza A. Shamshirsaz, Timothy C. Lee, Sundeep G. Keswani, Alice King, Nancy A. Ayres, Caraciolo J. Fernandes, Magdalena Sanz-Cortes, Ahmed A. Nassr, Andres F. Espinoza, Candace C. Style, Jimmy EspinozaBaylor College of Medicine.United States Journal of Maternal Fetal and Neonatal MedicineJ Mat Fetal Neonat Med 2022; 35: 6967-6972DOI: 10.1080/14767058.2021.1932806 AbstractObjective: To study

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Diagnosis and management of pulmonary hypertension in congenital diaphragmatic hernia

Shazia Bombal, Neil PatelStanford University and Lucille Packard Children’s Hospital. Royal Hospital for Children, Glasgow. United States and United Kingdom Seminars in Fetal and Neonatal MedicineSemin Fetal Neonatal Med 2022; 27: DOI: 10.1016/j.siny.2022.101383 AbstractCongenital diaphragmatic hernia (CDH) contributes to neonatal morbidity and mortality worldwide. Pulmonary hypertension (PH) is a key component of CDH pathophysiology and critical

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