Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

Amniotic fluid stem cell extracellular vesicles as a novel fetal therapy for pulmonary hypoplasia: a review on mechanisms and translational potential

Fabian Doktor, Lina Antounians, Rebeca Lopes Figueira, Kasra Khalaj, Miriam Duci, Augusto ZaniHospital for Sick Children and University of Toronto. Leipzig University.Canada and Germany Stem Cells Translational MedicineStem Cells Transl Med 2025; 14: DOI: 10.1093/stcltm/szae095 AbstractDisruption of developmental processes affecting the fetal lung leads to pulmonary hypoplasia. Pulmonary hypoplasia results from several conditions including congenital diaphragmatic […]

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Postnatal management of preterm infants with congenital diaphragmatic hernia

Emma Williams, Stephanie Lau, Nimrah Abbasi, Eveline Lapidus-Krol, Priscilla P. L. Chiu, Brian T. KalishHospital for Sick Children and University of Toronto. Mount Sinai Hospital. Canada Pediatric Surgery InternationalPediatr Surg Int 2025; 41: DOI: 10.1007/s00383-025-05964-5 AbstractIntroduction: Congenital diaphragmatic hernia (CDH) in the preterm population is increasingly common in the current era of fetal endoluminal tracheal occlusion (FETO)

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Spondylo-Thoracic Dysplasia: Survival, a Rare Occurrence

Upendra P. Sahu, Rufeena J, Suman Kumar, Nimisha VatsanaRajendra Institute of Medical Sciences.India CureusCureus 2024; 16: DOI: 10.7759/cureus.74894 AbstractSpondylo-thoracic dysplasia (STD) is a set of rare congenital abnormalities involving the vertebrae and thorax, leading to significant morbidity and mortality due to respiratory insufficiency and associated anomalies. Clinically, neonates present with scoliosis, vertebral segmentation defects, and severe

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Congenital heart disease and arrhythmia disorders in newborns with congenital diaphragmatic hernia: a 23-year experience at a UK university pediatric surgical centre

Wan Teng Lee, Chun Sui Kwok, Paul D. LostyUniversity of Liverpool and Alder Hey Children’s Hospital. Ramathibodi Hospital.United Kingdom and Thailand Pediatric Surgery InternationalPediatr Surg Int 2024; DOI: 10.1007/s00383-024-05927-2 AbstractPurpose: Congenital diaphragmatic hernia (CDH) is associated with congenital heart disease (CHD) and index newborns reportedly may experience cardiac arrhythmia disorders [Tella et al.-Pediatric Critical Care Medicine 2022].

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Enhancing the Survival of Congenital Diaphragmatic Hernia: Quality Improvement Initiative With a Multidisciplinary Extracorporeal Membrane Oxygenation Team Approach

Byong Sop Lee Jiyoon Jeong, Euiseok Jung, Ha Na Lee, Heeyoung Kim, Hyunhee Kwon, Soo Hyun Kim, Jung-Man Namgoong, Dae Yeon KimAsan Medical Center, Asan Medical Center Children’s Hospital and University of Ulsan College of Medicine. Republic of Korea Journal of Korean Medical ScienceJ Korean Med Sci 2024; 39: DOI: 10.3346/jkms.2024.39.e300 AbstractBackground: Extracorporeal membrane oxygenation (ECMO) is

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Echocardiographic Changes in Infants with Severe Congenital Diaphragmatic Hernia After Fetoscopic Endoluminal Tracheal Occlusion (FETO)

Catherine M. Avitabile, Sabrina Flohr, Leny Mathew, Yan Wang, Devon Ash, Juliana S. Gebb, Natalie E. Rintoul, Holly L. HedrickUniversity of Pennsylvania Perelman School of Medicine and Children’s Hospital of Philadelphia. United States Pediatric CardiologyPediatr Cardiol 2024; DOI: 10.1007/s00246-024-03735-y AbstractFetoscopic endoluminal tracheal occlusion (FETO) induces lung growth and may improve survival in congenital diaphragmatic hernia (CDH)

Echocardiographic Changes in Infants with Severe Congenital Diaphragmatic Hernia After Fetoscopic Endoluminal Tracheal Occlusion (FETO) Read More »

Treprostinil Use in the NICU

Diana LeeUniversity of Pennsylvania School of Nursing.United States Advances in Neonatal CareAdv Neonat Care 2024; 24: 554-560DOI: 10.1097/ANC.0000000000001218 AbstractBackground: Treprostinil is a prostacyclin analogue that is frequently used in the pediatric and adult population to treat pulmonary hypertension; however, it is not often a drug of choice for patients in the neonatal intensive care unit (NICU).Purpose: To evaluate

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Two-Year Outcomes in Preterm Infants Suffering from Moderate to Severe Bronchopulmonary Dysplasia with or without Associated Pulmonary Hypertension

Irina Branescu, Dragos Ovidiu Alexandru, Simona Vladareanu, Anay KulkarniCarol Davila University of Medicine and Pharmacy. St. George’s University Hospital and St George’s University. University of Medicine and Pharmacy. Royal Brompton Hospital NHS Foundation Trust.Romania and United Kingdom Current Health Sciences JournalCurr Health Sci J 2024; 50: 436-443DOI: 10.12865/CHSJ.50.03.11 AbstractObjectives: To assess the impact of pulmonary hypertension (PH)

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microRNAs in Congenital Diaphragmatic Hernia: Insights into Prenatal and Perinatal Biomarkers and Altered Molecular Pathways: microRNAs in Congenital Diaphragmatic Hernia for Pathway Analysis and Prognostic Biomarkers

James R. Bardill, Anis Karimpour-Fard, Courtney C. Breckenfelder, Carmen C. Sucharov, Caitlin R. Eason, Lauren T. Gallagher, Ludmila Khailova, Clyde J. Wright, Jason Gien, Henry L. Galan, S. Christopher DerderianUniversity of Colorado School of Medicine and Children’s Hospital Colorado. United States American Journal of Obstetrics and Gynecology Maternal and Fetal MedicineAm J Obstet Gynecol MFM

microRNAs in Congenital Diaphragmatic Hernia: Insights into Prenatal and Perinatal Biomarkers and Altered Molecular Pathways: microRNAs in Congenital Diaphragmatic Hernia for Pathway Analysis and Prognostic Biomarkers Read More »

The cardiopulmonary benefits of physiologically based cord clamping persist for at least 8 hours in lambs with a diaphragmatic hernia

Paige J. Riddington, Philip L. J. DeKoninck, Marta Thio, Calum T. Roberts, Risha Bhatia, Janneke Dekker1, Aidan J. Kashyap, Benjamin J. Amberg, Karyn A. Rodgers, Alison M. Thiel, Ilias Nitsos, Valerie A. Zahra, Ryan J. Hodges, Stuart B. Hooper, Kelly J. CrossleyHudson Institute of Medical Research. Monash University. Erasmus MC University Medical Center-Sophia Children’s Hospital.

The cardiopulmonary benefits of physiologically based cord clamping persist for at least 8 hours in lambs with a diaphragmatic hernia Read More »

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