Class 3. Pulmonary Hypertension Associated with Lung Disease

Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension: Basing Care on Physiology

Paula Dias Maia, Steven H. Abman, Erica MandellUniversity of Colorado Anschutz School of Medicine and Children’s Hospital Colorado. United States NeoreviewsNeoreviews 2024; 25: e415-e433DOI: 10.1542/neo.25-7-e415 AbstractBronchopulmonary dysplasia (BPD) is the heterogeneous chronic lung developmental disease of prematurity, which is often accompanied by multisystem comorbidities. Pulmonary vascular disease and pulmonary hypertension (PH) contribute significantly to the pathogenesis […]

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Achieved oxygen saturations and risk for bronchopulmonary dysplasia with pulmonary hypertension in preterm infants

Samuel J. Gentle, Avinash Singh, Colm P. Travers, Arie Nakhmani, Waldemar A. Carlo, Namasivayam AmbalavananUniversity of Alabama at Birmingham.United States Archives of Disease in ChildhoodArch Dis Child 2024; DOI: 10.1136/archdischild-2024-327014 AbstractObjective: Characterisation of oxygen saturation (SpO2)-related predictors that correspond with both bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) development and survival status in infants with BPD-PH may improve patient outcomes.

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The Epidemic of Congenital Syphilis in the Indigenous and Rural Populations of South Dakota

Narysse Nicolet, Amrita Bhagia, Megan Torve, Kessa Tribby, Nicole Poppinga, Kimberlee McKay, Maria M. Talavera-BarberUniversity of South Dakota Sanford School of Medicine. Monument Health. Avera McKennan Hospital and University Health CenterUnited States PediatricsPediatrics 2024; DOI: 10.1542/peds.2023-063823 AbstractFrom 2020 to 2023, South Dakota witnessed a substantial increase in cases of congenital syphilis (CS), with the highest rates

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Navigating Diagnostic and Treatment Challenges of Pulmonary Hypertension in Infants with Bronchopulmonary Dysplasia

Nidhy P. Varghese, Gabriel Altit, Megan M. Gubichuk, Roopa SiddaiahBaylor College of Medicine and Texas Children’s Hospital. Montreal Children’s Hospital and McGill University. Children’s Mercy Hospital. Penn State Health Children’s Hospital.United States and Canada Journal of Clinical MedicineJ Clin Med 2024; 13: DOI: 10.3390/jcm13123417 AbstractAdvances in perinatal intensive care have significantly enhanced the survival rates of

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Safety and Tolerability of Continuous Inhaled Iloprost Therapy for Severe Pulmonary Hypertension in Neonates and Infants

Amit V. Krishnan, Victoria Freniere, Rakesh Sahni, Diana P. Vargas Chaves, Sankaran S. Krishnan, Dimitrios Savva, Usha S. KrishnanColumbia University Irving Medical Center and New York-Presbyterian Hospital. New York Medical College.United States ChildrenChildren 2024; DOI: 10.3390/children11060703 AbstractThis is a single-center retrospective study to assess the safety and tolerability of continuous inhaled iloprost use as rescue therapy

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Elevated pulmonary capillary wedge pressure, higher blood pressure, and lower cardiac index in infants with bronchopulmonary dysplasia

Cathereine M. Avitable, Xuemei Zhang, Steve Ampah, Yan Wang, Devon Ash, Kathleen Nilan, Jennifer E. Tingo, David B. Frank, Erik A. Jensen, Krithika Lingappan, Kathleen A. GibbsThe Children’s Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania. United States Internation Journal of CardiologyInt J Cardiol 2024; DOI: 10.1016/j.ijcard.2024.132246 AbstractBackground: Left ventricular diastolic dysfunction

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Improvement in Echocardiographic and Diagnostic Biomarkers after Systemic Glucocorticoid Therapy in Infants with Pulmonary Hypertension

Brian S. Hernandez, Rod M. Shinozaki, R. Mark Grady, Andrea Drussa, Erica Jamro-Comer, Jinli Wang, Manish AggarwalWashington University School of Medicine. Loma Linda University Children’s Hospital. United States Journal of PediatricsJ Pediatr 2024; DOI: 10.1016/j.jpeds.2024.114116 AbstractObjective: To assess the effect of treating pulmonary hypertension (PH) in infants less than 1 year of age with systemic glucocorticoids while

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Neonatal outcomes of preterm infants with pulmonary hypertension: clustering based on prenatal risk factors

Seong Phil Bae, Sung Shin Kim, Jungha Yun, Hanbyul Lee, Won-Ho Hahn, Suyeon ParkSoonchunhyang University Seoul Hospital, Bucheon Hospital, and College of Medicine. Catholic University of Korea Eunpyeong St. Mary’s Hospital. Inha University Hospital. Chung-Ang University.Republic of Korea Pediatric ResearchPediatr Res 2024; DOI: 10.1038/s41390-024-03232-1 AbstractBackground: To investigate association of prenatal risk factors and neonatal outcomes of preterm

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A comprehensive study on machine learning models combining with oversampling for bronchopulmonary dysplasia-associated pulmonary hypertension in very preterm infants

Dan Wang, Shuwei Huang, Jingke Cao, Zhichun Feng, Qiannan Jiang, Wanxian Zhang, Jia Chen, Shelby Kutty, Changgen Liu, Wenyu Liao, Le Zhang, Guli Zhu, Wenhao Guo, Jie Yang, Lin Liu, Jingwei Yang, Qiuping LiSeventh Medical Center of PLA General Hospital. Second School of Clinical Medicine, Southern Medical University. Hunan Children’s Hospital. Tsinghua University. Qingdao Women

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Correlating Severity of Pulmonary Hypertension by Echocardiogram with Mortality in Premature Infants with Bronchopulmonary Dysplasia

Rachel D. Torok, Robert A. Gardner, Piers C.A. Barker, Andrew W. McCrary, Jennifer S. Li, Christoph P. Hornik, Matthew M. Laughon, Wesley M. JacksonDuke University Medical Center. University of North Carolina at Chapel Hill. United States American Journal of PerinatologyAm J Perinatol 2024; DOI: 10.1055/s-0044-1786544 AbstractObjective: Bronchopulmonary dysplasia (BPD) is the most common complication of preterm birth. Infants with BPD are at increased risk

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