Class 3. Pulmonary Hypertension Associated with Lung Disease

Type 2 immune polarization is associated with cardiopulmonary disease in preterm infants

Jason C. Lao, Christine B. Bui, Merrin A. Pang, Steven X. Cho, Ina Rudloff, Kirstin Elgass, Jan Schroder, Anton Maksimenko, Niamh E. Mangan, Malcolm R. Starkey, Elisabeth M. Skuza, Yu B. Y. Sun, Friederike Beker, Clare L. Collins, Omar F. Kamlin, Kai Konig, Atul Malhotra, Kenneth Tan, Chritiane Theda, Morag J. Young, Catriona A. McLean, […]

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Thrombospondin-1 Plays a Major Pathogenic Role in Experimental and Human Bronchopulmonary Dysplasia

Brittany Ann Ruschkowski, Yousef Esmaeil, Kate Daniel, Chantel Gaudet, Behzad Yeganeh, David Grynspan, Robert P. JankovChildren’s Hospital of Eastern Ontario Research Institute. University of Ottawa.Canada American Journal of Respiratory and Critical Care MedicineAm J Respir Crit Care Med 2022; 205: 685-699DOI: 10.1164/rccm.202104-1021OC AbstractRationale: Extremely preterm infants develop bronchopulmonary dysplasia (BPD), a chronic lung injury that lacks effective

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Effects of a Long-Term Wearable Activity Tracker-Based Exercise Intervention on Cardiac Morphology and Function of Patients with Cystic Fibrosis

Maria Anifanti, Stavros Giannakoulakos, Elpis Hatziagorou, Asterios Kampouras, John Tsanakas, Asterios Deligiannis, Evangelia KouidiAristotle University of Thessaloniki and Hippokration Hospital. Greece SensorsSensors 2022; 22: DOI: 10.3390/s22134884 AbstractSeveral studies have shown that patients with cystic fibrosis (CF), even at a young age, have pulmonary and cardiac abnormalities. The main complications are cardiac right ventricular (RV) systolic and/or

Effects of a Long-Term Wearable Activity Tracker-Based Exercise Intervention on Cardiac Morphology and Function of Patients with Cystic Fibrosis Read More »

Risk Factors of Neonatal Acute Respiratory Distress Syndrome Based on the Montreux Definition in Neonates with Sepsis: A Retrospective Case-Control Study

Ya Hu, Kinhong Chen, Fang Wang, Chun Li, Weighong Yue, Hong WeiChildren’s Hospital of Chongqing Medical University. Ministry of Education Key Laboratory of Child Development and Disorders. National Clinical Research Center for Child Health and Disorders (Chongqing). China International Science and Technology Cooperation base of Child development and Critical Disorders. Chongqing Key Laboratory of Pediatrics.China

Risk Factors of Neonatal Acute Respiratory Distress Syndrome Based on the Montreux Definition in Neonates with Sepsis: A Retrospective Case-Control Study Read More »

Clinical characteristics and outcomes in neonates with perinatal acute respiratory distress syndrome in China: A national, multicentre, cross-sectional study

Long Chen, Jie Li, Yuan Shi, Chinese Neonatal ARDS (ChiNARDS) study groupChildren’s Hospital of Chongqing Medical University. The First Affiliated Hospital of Chongqing Medical University.China eClinicalMedicineeClinicalMedicine 2022; 55: DOI: 10.1016/j.eclinm.2022.101739 AbstractBackground: Neonatal acute respiratory distress syndrome (NARDS) was defined in 2017 and the epidemiological data remain unknown. Our objective was to explore aetiological factors, clinical characteristics and

Clinical characteristics and outcomes in neonates with perinatal acute respiratory distress syndrome in China: A national, multicentre, cross-sectional study Read More »

Pilot study for comparative assessment of dual-energy computed tomography and single-photon emission computed tomography V/Q scanning for lung perfusion evaluation in infants

Karen I. Ramirez-Suarez, Christian A. Barrera, Hansel J. Otero, David M. Biko, Lisa J. States, Sabah Servaes, Xiaowei Zhu, James C. Davis, Josrph Piccione, Jordan B. RappChildren’s Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine. West Virginia University Medicine Children’s Hospital.United States Pediatric PulmonologyPediatr Pulmonol 2022; 57: 702-710DOI: 10.1002/ppul.25788 AbstractObjective: To evaluate clinical applications

Pilot study for comparative assessment of dual-energy computed tomography and single-photon emission computed tomography V/Q scanning for lung perfusion evaluation in infants Read More »

Growth and differentiation factor 15 (GDF15) levels predict adverse respiratory outcomes in premature neonates

Faeq Almudares, Joseph Hagan, Xinpu Chen, Sridevi Devaraj, Bhagavatula Moorthy, Krithika LingappanBaylor College of Medicine. Children’s Hospital of Philadelphia.United States Pediatric PulmonologyPediatr Pulmonol 2023; 58: 271-278DOI: 10.1002/ppul.26197 AbstractGrowth and differentiation factor 15 (GDF15) is a stress-responsive cytokine, and its expression increases during inflammation, hyperoxia, and senescence. Significantly, GDF15 is secreted by the placenta, and maternal levels

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Assessing the impact of gestational age of donors on the efficacy of amniotic epithelial cell-derived extracellular vesicles in experimental bronchopulmonary dysplasia

Dandan Zhu, Mirja Krause, Tamara Yawno, Gina D. Kusuma, Renate Schwab, Mehri Barabadi, Amina S. Maleken, Siow T. Chan, Rod Hunt, David Greening, Euan M. Wallace, Rebecca LimHudson Institute of Medical Research. Monash University. La Trobe Institute for Molecular Science and La Trobe University. University of Melbourne.Australia Stem Cell Research and TherapyStem Cell Res Ther

Assessing the impact of gestational age of donors on the efficacy of amniotic epithelial cell-derived extracellular vesicles in experimental bronchopulmonary dysplasia Read More »

Prospective Risk Stratification Identifies Healthcare Utilization Associated with Home Oxygen Therapy for Infants with Bronchopulmonary Dysplasia

Joanne M. Lagatta, Liyun Zhang, Ke Yan, Sara Dawson, Michael E. Msall, Namasivayam Ambalavanan, David C. BrousseauMedical College of Wisconsin. University of Chicago. University of Alabama at Birmingham.United States Journal of PediatricsJ Pediatr 2022; 251: 105-112DOI: 10.1016/j.jpeds.2022.07.040 AbstractObjective: To test whether prospective classification of infants with bronchopulmonary dysplasia identifies lower-risk infants for discharge with home oxygen who

Prospective Risk Stratification Identifies Healthcare Utilization Associated with Home Oxygen Therapy for Infants with Bronchopulmonary Dysplasia Read More »

Cardiorespiratory adaptation to low-dose dexamethasone for lung disease in extremely preterm infants: A prospective echocardiographic study

Arvind Sehgal, Marcel F. Nold, Calum T. Roberts, Samuel MenahemMonash Children’s Hospital, Monash Medical Centre and Monash University. Hudson Institute of Medical Research.Australia Journal of PhysiologyJ Physiol 2022; 600: 4361-4373DOI: 10.1113/JP282973 AbstractThe cardiovascular impact of dexamethasone (Dex) is not well understood. Most data are obtained from a 6 week, high-dose regimen, and are limited to findings

Cardiorespiratory adaptation to low-dose dexamethasone for lung disease in extremely preterm infants: A prospective echocardiographic study Read More »

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