Class 3. Pulmonary Hypertension Associated with Lung Disease

Targeted neonatal echocardiography and lung ultrasound in preterm infants with chronic lung disease with and without pulmonary hypertension, screened using a standardized algorithm

Janneth Cristina Sánchez-Becerra, Rogelio Guillén-Torres, Rosario Becerra-Becerra, Horacio Márquez-González, Daniel Ibarra-RíosNational Institute of Health and Hospital Infantil de México Federico Gómez.Mexico Frontiers in PediatricsFront Pediatr 2023; 11: DOI: 10.3389/fped.2023.1104940 AbstractIntroduction: Increased recognition of the development of chronic pulmonary hypertension (cPH) in preterm infants with chronic lung disease (CLD) has prompted enhanced monitoring for the identification of different […]

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Association of newer definitions of bronchopulmonary dysplasia with pulmonary hypertension and long-term outcomes

Jae Kyoon Hwang, Seung Han Shin, Ee-Kyung Kim, Seh Hyun Kim, Han-Suk KimHanyang University Guri Hospital. Seoul National University College of Medicine.Republic of Korea Frontiers in PediatricsFront Pediatr 2023; 11: DOI: 10.3389/fped.2023.1108925 AbstractBackground: The definition of bronchopulmonary dysplasia (BPD) has been evolved recently from definition by the National Institute of Child Health and Human Development in 2001

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Outcomes of and factors associated with the development of bronchopulmonary dysplasia with pulmonary hypertension in very low birth weight infants: A retrospective study in a medical center

Han-Pi Chang, Reyin Lien, Shih-Ming Chu, Jainn-Jim Lin, Ming-Chou ChiangChang Gung Memorial Hospital and Chang Gung University College of Medicine. New Taipei Municipal TuCheng Hospital. Taiwan Frontiers in PediatricsFront Pediatr 2023; 11: DOI: 10.3389/fped.2023.1055439 AbstractIntroduction: Bronchopulmonary dysplasia (BPD) with pulmonary hypertension (PH) leads to increased morbidity and mortality in extremely preterm infants. Recent studies have analyzed factors

Outcomes of and factors associated with the development of bronchopulmonary dysplasia with pulmonary hypertension in very low birth weight infants: A retrospective study in a medical center Read More »

Multiomics endotyping of preterm infants with bronchopulmonary dysplasia and pulmonary hypertension-A pilot study

Roopa Siddaiah, Christiana Oji‐Mmuo, Vincent P. R. Aluquin, Yuka Imamura Kawasawa, Ann Donnelly, Dustin Rousselle, Nathalie Fuentes, Eric D. Austin, Patricia SilveyraPenn State Health and Children’s Hospital. Indiana University School of Public Health. Vanderbilt University.United States Pulmonary CirculationPulm Circ 2023; 13: DOI: 10.1002/pul2.12232 Abstract Pulmonary hypertension associated with bronchopulmonary dysplasia is a severe complication of preterm

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Pharmacotherapy for Pulmonary Hypertension in Infants with Bronchopulmonary Dysplasia: Past, Present, and Future

Candice D. Fike, Judy L. AschnerUniversity of Utah Health. Joseph M. Sanzari Children’s Hospital at Hackensack University.United States PharmaceuticalsPharmaceuticals 2023; 16: DOI: 10.3390/ph16040503 AbstractApproximately 8-42% of premature infants with chronic lung disease of prematurity, bronchopulmonary dysplasia (BPD), develop pulmonary hypertension (PH). Infants with BPD-PH carry alarmingly high mortality rates of up to 47%. Effective PH-targeted pharmacotherapies

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Diagnosis and management of pulmonary hypertension in infants with bronchopulmonary dysplasia: a guide for paediatric respiratory specialists

Sarah Chan, Rossa Brugha, Sadia Quyam, Shahin MoledinaGreat Ormond Street Hospital for Children. NHS Foundation Trust. University College London, London. United Kingdom BreatheBreathe 2022; 18: DOI: 10.1183/20734735.0209-2022 AbstractPulmonary hypertension (PH) can develop in babies with bronchopulmonary dysplasia (BPD). PH is common in those with severe BPD and is associated with a high mortality rate. However, in

Diagnosis and management of pulmonary hypertension in infants with bronchopulmonary dysplasia: a guide for paediatric respiratory specialists Read More »

First Genotype-Phenotype Study in TBX4 Syndrome: Gain-of-Function Mutations Causative for Lung Disease

Matina Prapa, Mauro Lago-Docampo, Emilia M. Swietlik, David Montani, Melanie Eyries, Marc Humbert, Carrie L. Welch, Wendy K. Chung, Rolf M. F. Berger, Harm Jan Bogaard, Olivier Danhaive, Pilar Escribano-Subıas, Henning Gall, Barbara Girerd, Ignacio Hernandez-Gonzalez, Simon Holden, David Hunt, Samara M. A. Jansen, Wilhelmina Kerstjens-Frederikse, David G. Kiely, Pablo Lapunzina, John McDermott, Shahin Moledina,

First Genotype-Phenotype Study in TBX4 Syndrome: Gain-of-Function Mutations Causative for Lung Disease Read More »

Hypoxic preconditioning improves the survival and pro-angiogenic capacity of transplanted human umbilical cord mesenchymal stem cells via HIF-1α signaling in a rat model of bronchopulmonary dysplasia

Chang Hao, Jingyi You, Huijun Qiu, Ou Zhou, Jiang Liu, Wenjing Zou, Ke Yeng, Zhou Fu, Lin ZouChildren’s Hospital of Chongqing Medical University. China Biochemical and Biophysical Research CommunicationsBiochem Biophys Res Commun 2022; 605: 111-118DOI: 10.1016/j.bbrc.2022.03.044 AbstractBronchopulmonary dysplasia (BPD) is a serious chronic respiratory disease that predominates in the neonatal period. Currently, efficacious and effective specific

Hypoxic preconditioning improves the survival and pro-angiogenic capacity of transplanted human umbilical cord mesenchymal stem cells via HIF-1α signaling in a rat model of bronchopulmonary dysplasia Read More »

Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant

Motaharehsadat Heydarian, Prajakta Oak, Xin Zhang, Nona Kamgari, Alida Kindt, Markus Koschlig, Tina Pritzke, Erika Gonzalez- Rodriguez, Kai Förster, Rory E Morty, Friederike Häfner, Christoph Hübener, Andreas W Flemmer, Ali Oender Yildirim, Deepti Sudheendra, Xuefei Tian, Agnese Petrera, Holger Kirsten, Peter Ahnert, Nick Morrell, Tushar J Desai, Jennifer Sucre, Edda Spiekerkoetter, Anne HilgendorffHelmholtz Zentrum München.

Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant Read More »

Risk factors that affect the degree of bronchopulmonary dysplasia in very preterm infants: a 5-year retrospective study

Tingting Yang, Qianqian Shen, Siyu Wang, Tianfang Dong, Liang Liang, Fan Xu, Youfang He, Chunlei Li, Fang Luo, Jiahong Liang, Chunhui Tang, Jinghui YangKunming University of Science and Technology. The First People’s Hospital of Yunnan Province. Dali University. The First Hospital of Kunming. Yunnan University of Traditional Chinese Medicine. The Affiliated Hospital of Kunming University

Risk factors that affect the degree of bronchopulmonary dysplasia in very preterm infants: a 5-year retrospective study Read More »

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