Class 3. Pulmonary Hypertension Associated with Lung Disease

Does inhaled nitric oxide treatment of pulmonary hypertension in extremely premature infants improve patient outcomes?

Tyler L. King, Patrick J. McNamara, Adrianne R. BischoffUniversity of Iowa.United States Journal of PerinatologyJ Perinatol 2026; DOI: 10.1038/s41372-026-02666-1 AbstractAbstract Not Available CategoryClass III. Pulmonary Hypertension Associated with Lung DiseaseMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access […]

Does inhaled nitric oxide treatment of pulmonary hypertension in extremely premature infants improve patient outcomes? Read More »

Sildenafil for bronchopulmonary dysplasia-associated pulmonary hypertension: A systematic search and narrative synthesis

Yoshinori Katayama, Katsuya Hirata, Yutaka Nishimura, Atsuko, Nakahari, Mami Takeoka, Masahiko Watanabe, Tetsuya Isayama, Japan Evidence Based NeonatologyTakatsuki General Hospital. Osaka Women’s and Children’s Hospital. Hiroshima City Hiroshima Citizens Hospital. Jichi Medical University Saitama Medical Center. Mie University Graduate School of Medicine. National Center for Child Health and Development.Japan Pediatrics InternationalPediatr Int 2026; 68: DOI: 10.1111/ped.70385

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Postnatal Steroids in Preterm Infants: A Narrative Review Series-Part 2: Cardiovascular Impacts

Phoenix Plessas-Azurduy, Anie Lapointe, Punnanee Wutthigate, Sarah Spénard, Andréanne Villeneuve, Audrey Hébert, Eilon Shany, Justin Richardson, Neta Geva, Wadi Mawad, Tiscar Cavallé-Garrido, Marc Beltempo, Wissam Shalish, Guilherme Sant’Anna, Gabriel AltMcGill University. Université de Montréal, CHU Sainte-Justine. Mahidol University. Montreal Children’s Hospital. CHU de Québec and Laval University. Saban Children’s Hospital and Soroka Medical Center. Ben

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Mitochondria-derived peptide MOTS-c alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice by activating Nrf2 pathway

Dan Chen, Mei-hui Zhou, Wei-ying Zhu, Zhi-xuan Xing, Sheng-peng Li, Ya-xian Wu, Xiao-lin Sun, Ping Sun, Qing-feng PangWuxi School of Medicine, Jiangnan University Medical Center and Jiangnan University. Maternity and Child Health Care Affiliated Hospital, Jiaxing University. Linyi Maternal and Child Health Hospital. China European Journal of PharmacologyEur J Pharmacol 2026; DOI: 10.1016/j.ejphar.2026.178726 AbstractOxidative stress play

Mitochondria-derived peptide MOTS-c alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice by activating Nrf2 pathway Read More »

Relationships between lung ultrasound, chest CT, and echocardiographic findings in children with bronchopulmonary dysplasia: A multimodal imaging study

Andrea Maria Comisi, Giuseppe Fabio Parisi, Francesco Fabrizio Comisi, Salvatore Carnazzo, Pietro Sciacca, Alessandra Li Pomi, Sara Manti, Salvatore LeonardiSan Marco Hospital and University of Catania. Microcitemico Hospital “A. Cao” and University of Cagliari. University of Enna “Kore”. University of Messina. Italy Respiratory MedicineRespir Med 2026; DOI: 10.1016/j.rmed.2026.108775 AbstractThis study investigates the use of integrated imaging

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Pulmonary Hypertension in Infants Who Are Premature

Ana Beatriz Nevarez Gilbert, Adrianne R. BischoffUniversity of Iowa.United States NeoReviewsNeoreviews 2026; 27: e144-e156DOI: 10.1542/neo.27-3-102 AbstractPulmonary hypertension (PH) is a serious and potentially life-threatening condition in neonates, often resulting from impaired transition from fetal to postnatal circulation. Although traditionally associated with elevated pulmonary vascular resistance and hypoxemic respiratory failure, PH in infants who are preterm encompasses

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Physiology-Based Diagnosis and Management of Bronchopulmonary Dysplasia Associated Pulmonary Hypertension (BPD-PH)

Yogen Singh, Sfurti Nath, Sheen Gahlaut, Belinda ChanUniversity of California Davis Health. Warren Alpert Medical School of Brown University. Lincoln College of Oxford University.United States and United Kingdom ChildrenChildren 2026; 13: DOI: 10.3390/children13020272 AbstractBronchopulmonary dysplasia (BPD) remains a major long-term morbidity among preterm infants. As lung-protective strategies advance and survival of extremely premature neonates improves, BPD

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Titrating cumulative neonatal hyperoxia in mice to model bronchopulmonary dysplasia severities

Brooke Dir, Raveena Mishra, Nicole Hennen, Emily Mooers, Ru-jeng Teng, Ganesh Konduri, Jeffrey L. Segar, Justin Grobe, Matthew R. Hodges, Gary C. MouradianMedical College of Wisconsin. United States American Journal of Respiratory Cell and Molecular BiologyAm J Respir Cell Mol Biol 2026; DOI: 10.1093/ajrcmb/aanag031 AbstractThe severity of bronchopulmonary dysplasia (BPD) is defined by the type or

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Peri and Neonatal Risk Factors and Structural Lung Abnormalities Predict Hypoxic Challenge Test Failure in Infants With Severe Bronchopulmonary Dysplasia

Kishan D. Tsang, Daan Caudri, Citta Zaat, Gerdien A. Tramper‐Stranders, Isme M. de Kleer, Pierluigi Ciet, Irwin K. M. Reiss, Liesbeth Duijts, Mariëlle W. PijnenburgErasmus Medical Centre, Sophia Children’s Hospital and University Medical Center. Franciscus Gasthuis & Vlietland. University of Cagliari. University Children’s Hospital, University Medical Center Hamburg Eppendorf. Netherlands, Italy, Germany Pediatric PulmonologyPediatr Pulmonol

Peri and Neonatal Risk Factors and Structural Lung Abnormalities Predict Hypoxic Challenge Test Failure in Infants With Severe Bronchopulmonary Dysplasia Read More »

Predicting pulmonary hypertension in infants with bronchopulmonary dysplasia

Henry P. Foote, Minghui Sun, Benjamin Alan Goldstein, Kevin D. Hill, Rachel G. Greenberg, Samuel J. Gentle, Kanecia O. Zimmerman, Rishikesan Kameleswaran, Veeral N. Tolia, Matthew M. Laughon, Wesley Jackson, Christoph P. HornikDuke University Medical Center and Duke University. Yale University School of Medicine. Baylor University Medical Center. University of North Carolina. United States Journal

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