Class 3. Pulmonary Hypertension Associated with Airway Disease, Apnea or Hypoventilation

[Pediatric pneumological aspects in the care of children with Down Syndrome]

Hans Fuchs, Lennart Gunst, Anke Wendt, Sebastian Becker, Ruth Margarethe Grychtol, Dejan Vlajnic, Dorit Aschmann-Muehlhans, Christiane Wuerfel, Mathis Steindor, Svea Muehlberg, Florian StehlingAlbert-Ludwigs-Universität Freiburg. Charité Universitätsmedizin Berlin. Darmstädter Kinderkliniken Prinzessin Margaret. Medizinische Hochschule Hannover. Klinikum Leverkusen. Kinderkrankenhaus St. Marien. Technische Universität Dresden. Heinrich-Heine-Universität Düsseldorf. Universitäts-Kinderspital Zürich. Universität Duisburg-Essen.Germany and Switzerland Klinische PädiatrieKlin Padiatr 2025; DOI: 10.1055/a-2748-4649 […]

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Novel Pulmonary Manifestations in Pediatric Late-Onset Congenital Central Hypoventilation Syndrome: A Case Series of PHOX2B-Associated Pulmonary Hypertension and Pulmonary Alveolar Hemorrhage

Yuhong Guan, Xiaohui Wen, Xiaoyan Zhang, zhifei Xu, Shunying Zhao, Haiming YangBeijing Children’s Hospital, Capital Medical University and National Center for Children’s Health.China Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71347 AbstractAnstract Not Available CategoryClass III. Pulmonary Hypertension Associated with Airway Disease, Apnea or HypoventilationSymptoms and Findings Associated with Pulmonary Vascular Disease Age Focus: Pediatric Pulmonary Vascular

Novel Pulmonary Manifestations in Pediatric Late-Onset Congenital Central Hypoventilation Syndrome: A Case Series of PHOX2B-Associated Pulmonary Hypertension and Pulmonary Alveolar Hemorrhage Read More »

Large Airway and Lung Findings in Symptomatic Children and Young Adults With Down Syndrome

Emily DeBoer, Kristine Wolter-Warmerdam, Francis Hickey, JAson WeinmanUniversity of Colorado School of Medicine and Children’s Hospital Colorado.United States Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71339 AbstractBackground and objectives: Epidemiology studies report pulmonary disease, lung infection, and pneumonia as the largest causes of morbidity and mortality in individuals with Down syndrome (DS), but how significant airway and lung

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Left Main Bronchus Stenosis Leading to Bronchiectasis and Pulmonary Hypertension- Relieved by Stent Placement

Patrick Stafler, Nili Schamroth, Arnon Elizur, Dario Prais, Eyal Jacobi, Zvi Bar-Sever, Tamir Dagan, Einat Birk, Elchanan BruckheimerSchneider Children’s Medical Center of Israel. Tel Aviv University. Rabin Medical Center. Yitzhak Shamir Medical Center. Israel Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71251 AbstractAbstract Not Available CategoryClass III. Pulmonary Hypertension Associated with Airway Disease, Apnea or HypoventilationSurgical and

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Prematurity and obstructive sleep apnea in children: The perfect storm

Oscar Camilo Pantoja-Gomez, Juanita Agudelo-Agudelo, Elida Duenas-Meza, Sonia M. Restrepo-Gualteros, Maria J. Gutierrez, Gustavo NinoUniversidad de La Sabana. Universidad Nacional de Colombia. Johns Hopkins University. Children’s National Hospital and George Washington University School of Medicine and Health Sciences.Columbia and United States Paediatric Respiratory ReviewsPaediatr Respir Rev 2025; DOI: 10.1016/j.prrv.2025.06.001 AbstractAs survival rates for premature infants improve,

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Right cardiac failure and pulmonary hypertension secondary to tonsil hypertrophy in a 3-year-old boy: a case report

Mehdi Berrajaa, Abdeladim Babakhouya, Mohamed El MinaouiSouss-Massa University Hospital and University Ibn Zohr. Mohammed VI University Hospital.Morocco PanAfrican Medical JournalPan Afr Med J 2025; DOI: 10.11604/pamj.2025.50.2.39678 AbstractIn children, the prevalence of obstructive sleep apnoea syndrome (OSAS) is 2 to 3%. Pulmonary hypertension-related OSAS in the context of tonsil hypertrophy is a well-documented phenomenon. However, cases combining

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Images: Atypical resolution of sleep-related hypoventilation in congenital central hypoventilation syndrome

Michelle Yoo, Amit Shah, Haitham Shahrour, Hong Li, Ajay S. KasiEmory University and Children’s Healthcare of Atlanta.United States Journal of Clinical Sleep MedicineJ Clin Sleep Med 2025;DOI: 10.5664/jcsm.11644 AbstractPaired-like homeobox 2B (PHOX2B) gene variants cause congenital central hypoventilation syndrome (CCHS) characterized by abnormal ventilatory control necessitating lifelong assisted ventilation (AV). We report a 3-year-old girl who

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A Comprehensive Review of Pediatric Obstructive Sleep Apnea: From Assessment to Intervention

Ulhas Jadhav, Jay Bhanushali, Arman Sindhu, Bingu Shiv Kiran Reddy, Amit Toshniwal, Mummaneni RashmikaJawaharlal Nehru Medical College and Datta Meghe Institute of Higher Education and Research.India CureusCureus 2025; 17: DOI: 10.7759/cureus.78051 AbstractPediatric obstructive sleep apnea (OSA) is a prevalent sleep disorder characterized by upper airway obstruction during sleep, leading to oxygen desaturation and sleep disruptions. This

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Trisomy 21 and Congenital Heart Disease: Impact on Health and Functional Outcomes From Birth Through Adolescence: A Scientific Statement From the American Heart Association

Jennifer K. Peterson, Shanelle Clarke, Bruce D. Gelb, Nadine A. Kasparian, Vanna Kazazian, Karyn Pieciak, Nancy A. Pike, Shaun P. Setty, Melissa K. Uveges, Nancy A. Rudd, the American Heart Association Pediatric Cardiovascular Nursing Committee of the Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; Council on Genomic and Precision Medicine; and Council on Cardiovascular Radiology and InterventionJohns Hopkins University School of Nursing. Children’s Hospital of Wisconsin. Children’s Healthcare Atlanta and Emory University.

Trisomy 21 and Congenital Heart Disease: Impact on Health and Functional Outcomes From Birth Through Adolescence: A Scientific Statement From the American Heart Association Read More »

NLRP3 Inflammasome Triggers Inflammation of Obstructive Sleep Apnea

Xiaoting Yangzhong, Shu Hua, Yiqiong Wen, Xiaoqing Bi, Min Li, Yuanyuan Zheng, Shibo SunFirst Affiliated Hospital, Kunming Medical University.China Current Molecular MedicineCurr Mol Med 2024; DOI: 10.2174/0115665240294605240426123650 AbstractObstructive sleep apnea [OSA] is widespread in the population and affects as many as one billion people worldwide. OSA is associated with dysfunction of the brain system that controls

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