Class 3. Pulmonary Hypertension Associated with Airway Disease, Apnea or Hypoventilation

Breathing challenges in achondroplasia: a comprehensive review of pediatric respiratory complications

Veronica Fasoli, Alessia Mariani, Federica Chironi, Mara Lelii, Barbara Madini, Beatrice Andrenacci, Alessia Rocchi, M. Francesca Bedeschi, M. Gaffuri, M. Pluderi, M. Francesca PatriaUniversità Degli Studi di Milano. Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico. Italy Paediatric Respiratory ReviewsPaediatr Respir Rev 2026; DOI: 10.1016/j.prrv.2026.05.003 AbstractAchondroplasia is the most common skeletal dysplasia, characterized by disproportionate short stature […]

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Association between upper airway obstruction and pulmonary hypertension in children with Down syndrome

Kevin Guy, Amal IsaiahUniversity of Maryland School of Medicine.United States Current Opinion in Pulmonary MedicineCurr Opin Pulm Med 2026; DOI: 10.1097/MCP.0000000000001287 AbstractPurpose of review: Down syndrome (DS) is the most common nonlethal chromosomal aneuploidy, affecting 1 in 700 live births. Pulmonary hypertension (PH) occurs in approximately 25% of children with DS and contributes to a 10% mortality

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Parental knowledge and awareness of complications of recurrent adenotonsillitis and its surgical management in children in the Jazan region, Saudi Arabia: a cross-sectional study

Abdulelah A. Otaif, Ramzi M. Dighriri, Abdulrahman A. Otaif, Riyadh A. Jahlan, Osama A. Alotayf, Ali Y. Shaikh, Saud N. Alwadani, Raghad M. Alnami, Asma M. SoweediJazan University, Jazan. Armed Forces Hospital.Saudi Arabia Frontiers in PediatricsFront Pediatr 2026; DOI: 10.3389/fped.2026.1761634 AbstractBackground: Recurrent adenotonsillitis is a frequent pediatric condition with complications affecting sleep, growth, hearing, and behavior. Parental

Parental knowledge and awareness of complications of recurrent adenotonsillitis and its surgical management in children in the Jazan region, Saudi Arabia: a cross-sectional study Read More »

Respiratory Syncytial Virus Infection Triggering a Pulmonary Hypertensive Crisis in a Boy With Prader-Willi Syndrome-Associated Sleep-Disordered Breathing

Mari Tsukahara, Hideaki Yagasaki, Koichi Makino, Tomoaki Sano, Takeshi InukaUniversity of Yamanashi.Japan CureusCureus 2026; 18: DOI: 10.7759/cureus.103890 AbstractPrader-Willi syndrome (PWS) is a multisystem genetic disorder frequently complicated by sleep-disordered breathing, including obstructive sleep apnea. Respiratory infections may precipitate acute decompensation in vulnerable patients with PWS. A four-year-old boy with genetically confirmed PWS receiving growth hormone therapy

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Obstructive Sleep Apnea-Hypopnea Syndrome in Children With Down Syndrome Treated at a Tertiary Care Hospital in Northeastern Colombia

Silvia N. Suarez Mantilla, Victor Manuel Mora Bautista, Martha Lucia Africano Leon, Diana C. Vergara Arenas, Yuli E. Rojas, Sergio Serrano-GomezUniversidad Industrial de Santander. Clinica Materno Infantil San Luis. Columbia CureusCureus 2026; 18: DOI: 10.7759/cureus.102624 AbstractObstructive sleep apnea-hypopnea syndrome (OSAHS) is frequent in children with Down Syndrome (DS), associated with anatomical characteristics such as midfacial hypoplasia,

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Mechanisms underlying end-organ injury in sleep apnea

Mohammad Badran, Rene Cortese, Alex Gileles-Hillel, David GozalUniversity of Missouri. University of Kansas Medical Center. Hebrew University of Jerusalem. Joan C. Edwards School of Medicine and Marshall University.United States and Israel European Respiratory JournalEur Respir J 2026; DOI: 10.1183/13993003.02397-2025 AbstractOSA is a prevalent chronic condition characterized by repetitive upper airway collapse that promotes the occurrence of

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Multidisciplinary care of pediatric obesity and its impact on sleep: a review

Ravali Inja, Christopher CieloChildren’s Hospital of Philadelphia.United States Frontiers in SleepFront Sleep 2026; 4: DOI: 10.3389/frsle.2025.1634185 AbstractPediatric obesity has emerged as a significant global health issue with multifaceted consequences, including its impact on sleep health. Obstructive sleep apnea (OSA) and obesity hypoventilation syndrome (OHS) are among the serious sleep-related comorbidities in obese children, contributing to impaired

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High-altitude pulmonary edema in children with underlying cardiopulmonary disorders and pulmonary hypertension living at altitude

Bibhuti B. Das, Robert R. Wolfe, Kak-Chen Chan, Gary L. Larsen, John T. Reeves, Dunbar IvyChildren’s Hospital, Denver.United States Archives of Pediatric and Adolescent MedicineArch Pediatr Adolesc Med 2004; 158: 1170-1176DOI: 10.1001/archpedi.158.12.1170 AbstractBackground: Pulmonary hypertension has not been described as a predisposing risk factor for high-altitude pulmonary edema (HAPE) in children. Previous studies have shown an association

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[Pediatric pneumological aspects in the care of children with Down Syndrome]

Hans Fuchs, Lennart Gunst, Anke Wendt, Sebastian Becker, Ruth Margarethe Grychtol, Dejan Vlajnic, Dorit Aschmann-Muehlhans, Christiane Wuerfel, Mathis Steindor, Svea Muehlberg, Florian StehlingAlbert-Ludwigs-Universität Freiburg. Charité Universitätsmedizin Berlin. Darmstädter Kinderkliniken Prinzessin Margaret. Medizinische Hochschule Hannover. Klinikum Leverkusen. Kinderkrankenhaus St. Marien. Technische Universität Dresden. Heinrich-Heine-Universität Düsseldorf. Universitäts-Kinderspital Zürich. Universität Duisburg-Essen.Germany and Switzerland Klinische PädiatrieKlin Padiatr 2025; DOI: 10.1055/a-2748-4649

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Novel Pulmonary Manifestations in Pediatric Late-Onset Congenital Central Hypoventilation Syndrome: A Case Series of PHOX2B-Associated Pulmonary Hypertension and Pulmonary Alveolar Hemorrhage

Yuhong Guan, Xiaohui Wen, Xiaoyan Zhang, zhifei Xu, Shunying Zhao, Haiming YangBeijing Children’s Hospital, Capital Medical University and National Center for Children’s Health.China Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71347 AbstractAnstract Not Available CategoryClass III. Pulmonary Hypertension Associated with Airway Disease, Apnea or HypoventilationSymptoms and Findings Associated with Pulmonary Vascular Disease Age Focus: Pediatric Pulmonary Vascular

Novel Pulmonary Manifestations in Pediatric Late-Onset Congenital Central Hypoventilation Syndrome: A Case Series of PHOX2B-Associated Pulmonary Hypertension and Pulmonary Alveolar Hemorrhage Read More »

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