Class 1. Pulmonary Hypertension Associated with Congenital Cardiovascular Disease

Porto-Pulmonary Hypertension in Children: Insights From a National Registry

Sadia Quyam, Alastair Baker, Alistair Calder, Shahin MoledinaGreat Ormond Street Hospital for Children. University College London. King’s College Hospital .Inited Kingdom Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70133 AbstractPorto-pulmonary hypertension (PoPH) represents a rare but significant form of pulmonary arterial hypertension (PAH) in children. Despite its clinical importance, systematic analyses of paediatric presentations and outcomes remain limited. […]

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Efficacy and Safety of Pulmonary Vasodilator and Inodilator Drugs in Congenital Heart Disease Surgery: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

Martina Ollosu, Vincenzo Francesco Tripodiy, Carlotta Aresu, Giammarco Ledda, Francesca Manai, Chiara Marini, Mario Musu, Mariachiara Ippolitoz, Andrea Cortegianiz, Gabriele Finco, Salvatore SardoUniversity of Cagliari. “Gaetano Martino” University Hospital. University Hospital Policlinico Paolo Giaccone. Italy Journal of Cardiothoracic and Vascular AnesthesiaJ Cardiothorac Vasc Anesth 2025; DOI: 10.1053/j.jvca.2025.08.053 AbstractBackground: Perioperative management of congenital heart disease (CHD) surgery presents

Efficacy and Safety of Pulmonary Vasodilator and Inodilator Drugs in Congenital Heart Disease Surgery: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials Read More »

Pulmonary Hypertension Outcomes After Closure of Atrial Septal Defect in Infants With Developmental Lung Disease

John L. Wiegand, James A. Thompson, Bruce F. Landeck, Jamie L. Fierstein, Dina Ashour, Joana S. Machry, Amy L. Kiskaddon, Marisol Betensky, Grace A. FreireUniversity of South Florida Morsani College of Medicine. Johns Hopkins All Children’s Hospital. United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70164 AbstractPulmonary hypertension (PHTN) in infants with developmental lung disease, such

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Microvascular preservation & cardiomyocyte hyperplasia underlie adaptive right ventricle development in congenital heart disease-pulmonary arterial hypertension

Michael A. Smith, Eleana S. Guardado, Jason Boehme, Sanjeev A. Datar, Emin Maltepe, Naveen Swami, Gary W Raff, Aaron Bodansky, Prakash Chelladurai, Joseph Moreno, Annelise Prince, Nevan Powers, Guo N. Huang, Vinicio de Jesus Perez, Jeffrey R. FinemanUniversity of California, San Francisco. Stanford University. United States American Journal of Physiology Heart and Circulatory PhysiologyAm J

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How Is Pulmonary Hypertension Characterised and Treated in Children With Trisomy 21? Observations From the TOPP Registry (Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension)

Tilman Humpl, Rolf M. F. Berger, Damien Bonnet, Maurice Beghetti, Dunbar Ivy, for the TOPP InvestigatorsDistrict Hospital of Loerrach Germany. Beatrix Children’s Hospital. Hôpital Necker Enfants Malades. Children’s University Hospital. Childrens Hospital Colorado and University of Colorado School of Medicine.Germany, Netherlands, France, Switzterland and United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70146 AbstractPulmonary hypertension is

How Is Pulmonary Hypertension Characterised and Treated in Children With Trisomy 21? Observations From the TOPP Registry (Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension) Read More »

Surviving trisomy 18: A case report of a 5-year-old girl

Mohamad A. Banat, Ramzi Mujahed, Sama S. Yaseen, Nada A. Makhalfeh, Shahed O. Rajabi, Baraa Abu Aisheh, Rama N. BasheerPalestine Polytechnic University. Princess Alia Governmental Hospital.Palestine MedicineMedicine 2025; 104: DOI: 10.1097/MD.0000000000044225 AbstractRationale: Trisomy 18, often known as Edwards syndrome. It is a common chromosomal disorder characterized by the presence of an extra chromosome 18. Unfortunately, survival past

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Early postnatal right-to-left patent ductus arteriosus shunting and severe outcomes in neonates with congenital diaphragmatic hernia: a retrospective cohort study

Jung Il Kwak, Juhee Park, Mi Jin Kim, Kyusang Yoo, Bo Kyeong Jin, Tae-Gyeong Kim, Joo Hyung Roh, Ha Na Lee, Keon Hee Seol, Chae Young Kim, Soo Hyun Kim, Jiyoon Jeong, Byong Sop Lee, Euiseok JungAsan Medical Center Children’s Hospital and University of Ulsan College of Medicine. BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-05986-x

Early postnatal right-to-left patent ductus arteriosus shunting and severe outcomes in neonates with congenital diaphragmatic hernia: a retrospective cohort study Read More »

Large Patent Ductus Arteriosus in an Adult With Severe Pulmonary Hypertension and Polycythemia: PDA With Severe Pulmonary Hypertension

Tyler L. Langenfeld, Maram Sati, Martin L. Bocks, Arpit K. AgarwalRainbow Babies and Children’s Hospital. United States Journal of the American College of CardiologyJACC Case Rep 2025; 30: DOI: 10.1016/j.jaccas.2025.104677 AbstractBackground: Patent ductus arteriosus (PDA) is one of the most common cardiac abnormalities in children, but in rare cases it can go undiagnosed into adulthood until symptoms

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General and Emergency Presentations of Children with Congenital Heart Defect and Factors Affecting it as Seen in A Tertiary Health Institution in Enugu

I. O. Arodiwe, I. A. Nwafor, F. A. Ujunwa, B. O. Edulu, J. M. Chinawa, T. A. Oguonu, N. Ezemba, J. C. EzeUniversity of Nigeria, Enugu Campus.Nigeria West Africa Journal of MedicineWest Africa J Med 2025; 42: 202-207DOI: Not Available AbstractBackground and objectives: The pattern of emergency presentations in children with congenital heart disease (CHD) is

General and Emergency Presentations of Children with Congenital Heart Defect and Factors Affecting it as Seen in A Tertiary Health Institution in Enugu Read More »

Case Report: Non-reactive vasoreactivity testing in a patient with patent ductus arteriosus with pulmonary hypertension: is there still a way to turn things around?

Sisca Natalia Siagian, Elsa Hedia Panjaitan, Pandu Prasetyo NugrohoUniversitas Indonesia.Indonesia Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2025; 12: DOI: 10.3389/fcvm.2025.1569963 AbstractBackground: Recent guidelines recommend patent ductus arteriosus (PDA) closure in adults based on hemodynamic criteria, such as pulmonary vascular resistance (PVR) and flow ratio (Qp:Qs). However, additional parameters like acute vasoreactivity testing (AVT) and closure testing, though

Case Report: Non-reactive vasoreactivity testing in a patient with patent ductus arteriosus with pulmonary hypertension: is there still a way to turn things around? Read More »

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