Class 1. Pulmonary Hypertension Associated with Congenital Cardiovascular Disease

Cause of death in children with heart disease: a cohort study

Neil Derridj, Daphné Madec, Olivier Raisky, Sophie Malekzadeh-Milani, Diala Khraiche, Antoine Legendre, Lucile Houyel, Zahra Belhadjer, Franck Iserin, Mathilde Méot, Marilyne Levy, Bertrand Stos, Daniela Laux, Victor Waldmann, Vanessa Lopez, Ayman Haydar, Segolene Bernheim, Régis Gaudin, Fanny Bajolle, Damien Bonnet, Members of M3C Necker Collaborative GroupHôpital Universitaire Necker-Enfants Malades. Paris Cité University. France Archives of […]

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Atrial Septal Defects: From Embryology to Pediatric Pulmonary Hypertension

Elzbieta Bartoszewska, Anna Chrapkowska, Oliwia Zielinska, Maria Mordalska, Julia Lizon, Zuzanna Zalewska, Marek WasicionekWroclaw Medical University. Poland Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14217698 AbstractAtrial septal defect (ASD) is characterized by an abnormal opening between the left (LA) and right atria (RA). Even though it’s one of the most prevalent congenital heart defects,

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Inhaled iloprost and 2D phase-contrast cardiac MRI in pulmonary vascular reversibility: an adolescent case of anomalous right pulmonary artery from the ascending aorta

Mete Han Kızılkaya, Mehmet Salih Bilal, Terman Gumus, Alpay ÇelikerUniversity School of Medicine. Medicana Health Group. Koc University School of Medicine. Turkey Cardiology in the YoungCardiol Young 2025; DOI: 10.1017/S1047951125109670 AbstractThe anomalous origin of the right pulmonary artery from the ascending aorta is a rare congenital anomaly usually diagnosed in infancy. When diagnosed later during adolescence,

Inhaled iloprost and 2D phase-contrast cardiac MRI in pulmonary vascular reversibility: an adolescent case of anomalous right pulmonary artery from the ascending aorta Read More »

Pulmonary Vascular Endothelial Dysfunction Is Induced by Nonpulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model

Jonathan Hyde, Michael A. Smith, Naveen Swami, John H. Hwang, Yenchun Chao, Jason Boehme,Gary W. Raff, Casper Noah Nilsson, Wenhui Gong, Gail H. Deutsch, Eric G. Johnson, Ting Wang,Stephen M. Black, Sanjeev A. Datar, Emin Maltepe, Jeffrey R. FinemanUniversity of California, San Francisco. Copenhagen University Hospital. University of Washington. University of California, Davis School of

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Phenoxybenzamine: Old Wine in a Bright New Bottle-Taming the wild side of Phenoxybenzamine

R. Benedict Raj, Srinath Reddy Narahari, Vasudev Vemala, Jyotiprakash ReddyAster Ramesh Hospitals.India Journal of Pharmacy and BioAllied SciencesJ Pharm Bioall Sci 2025; 17 (Suppl 3): S2135-S2137DOI: 10.4103/jpbs.jpbs_868_25 AbstractBackground: Phenoxybenzamine (PBZ), a long-acting α-blocker, was once widely used in pediatric cardiac surgeries but fell out of favor due to concerns about systemic hypotension. In the context of developing

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Treatment options for children with pulmonary arterial hypertension associated with congenital heart disease

Julie Wacker, Raphael Joye, Maurice BeghettiGeneva University Hospitals.Switzerland Expert Review of Respiratory MedicineExpert Rev Respir Med 2025; DOI: 10.1080/17476348.2025.2581340 AbstractIntroduction: Pulmonary hypertension associated with congenital heart disease (PAH-CHD) represents one of the leading causes of pediatric pulmonary hypertension. Within this entity, patients can be classified into distinct subgroups, each characterized by specific clinical features, pathophysiological mechanisms, and

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Persistence of pulmonary hypertension in patients with ventricular septal defect after intracardiac repair: insights from a long-term follow-up study

Yuko Walisaka, Kei Inai, Gen Harada, Seiji Asagai, Eriko ShimadaTokyo Women’s Medical University.Japan Cardiology in the YoungCardiol Young 2025; DOI: 10.1017/S1047951125110159 AbstractBackground: Ventricular septal defect is the most common CHD and is complicated by pulmonary hypertension in about 5% of cases. Although long-term outcomes after repair are generally good, persistent pulmonary hypertension has been reported, especially before

Persistence of pulmonary hypertension in patients with ventricular septal defect after intracardiac repair: insights from a long-term follow-up study Read More »

Successful percutaneous closure of ventricular septal defects associated with pulmonary hypertension using different atrial septal defect Occluders: A report of two cases

José Luis Colín-Ortiz, Rogelio Zúñiga-Gordillo, Linda Fabiola Pérez-Pérez, Carlos Balcázar-Ochoa, Roberto Tepatzi-Carranco, Rosa María García-MejíaHospital of Poblano Child. Southern General Hospital of Puebla. Tlaxcala’s Children Hospital.Mexico Journal of Cardiology CasesJ Cardiol Cases 2025; 32: 171-174DOI: 10.1016/j.jccase.2025.06.010 AbstractWe present two cases of children with muscular ventricular septal defects (mVSD) and severe pulmonary hypertension. Both children successfully underwent

Successful percutaneous closure of ventricular septal defects associated with pulmonary hypertension using different atrial septal defect Occluders: A report of two cases Read More »

A multimodal multipath AI system for assessing PAH after VSD correction on echocardiography and chest radiography images

Gang Luo, Huashu Liu, Zhixin Li, Zhixian Ji, Silin PanWomen and Children’s Hospital, Qingdao Central Hospital and Qindao Medical College of Qingdao University. China Scientific ReportsSci Rep 2025; 15: DOI: 10.1038/s41598-025-19584-5 AbstractDeveloping a novel artificial intelligence (AI) system that can automatically detect pulmonary arterial hypertension (PAH) after correcting the ventricular septal defect (VSD) and to help

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Comparative assessment of nutritional status in unoperated children with Congenital Heart Defects: Insights from a tertiary pediatric cardiac center in India

Radha Joshi, Manasi Bhoite, Poonam Mandhare, Shaoni Nath, Sudhir Kapoor1, Rishikesh Wadke, Ragini PandeySri Sathya Sai Sanjeevani Research Foundation and Centre for Child Heart Care and Training in Paediatric Cardiac Skills. India Public Library of Science Global Public HealthPLOS Glob Publi Health 2025; 5: DOI: 10.1371/journal.pgph.0005260 AbstractCongenital Heart Defects (CHD) are structural cardiac malformations ranging from

Comparative assessment of nutritional status in unoperated children with Congenital Heart Defects: Insights from a tertiary pediatric cardiac center in India Read More »

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