Class 1. Pulmonary Hypertension Associated with Congenital Cardiovascular Disease

Pulmonary Hypertension Outcomes After Closure of Atrial Septal Defect in Infants With Developmental Lung Disease

John L. Wiegand, James A. Thompson, Bruce F. Landeck, Jamie L. Fierstein, Dina Ashour, Joana S. Machry, Amy L. Kiskaddon, Marisol Betensky, Grace A. FreireUniversity of South Florida Morsani College of Medicine. Johns Hopkins All Children’s Hospital. United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70164 AbstractPulmonary hypertension (PHTN) in infants with developmental lung disease, such […]

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Microvascular preservation & cardiomyocyte hyperplasia underlie adaptive right ventricle development in congenital heart disease-pulmonary arterial hypertension

Michael A. Smith, Eleana S. Guardado, Jason Boehme, Sanjeev A. Datar, Emin Maltepe, Naveen Swami, Gary W Raff, Aaron Bodansky, Prakash Chelladurai, Joseph Moreno, Annelise Prince, Nevan Powers, Guo N. Huang, Vinicio de Jesus Perez, Jeffrey R. FinemanUniversity of California, San Francisco. Stanford University. United States American Journal of Physiology Heart and Circulatory PhysiologyAm J

Microvascular preservation & cardiomyocyte hyperplasia underlie adaptive right ventricle development in congenital heart disease-pulmonary arterial hypertension Read More »

How Is Pulmonary Hypertension Characterised and Treated in Children With Trisomy 21? Observations From the TOPP Registry (Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension)

Tilman Humpl, Rolf M. F. Berger, Damien Bonnet, Maurice Beghetti, Dunbar Ivy, for the TOPP InvestigatorsDistrict Hospital of Loerrach Germany. Beatrix Children’s Hospital. Hôpital Necker Enfants Malades. Children’s University Hospital. Childrens Hospital Colorado and University of Colorado School of Medicine.Germany, Netherlands, France, Switzterland and United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70146 AbstractPulmonary hypertension is

How Is Pulmonary Hypertension Characterised and Treated in Children With Trisomy 21? Observations From the TOPP Registry (Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension) Read More »

Surviving trisomy 18: A case report of a 5-year-old girl

Mohamad A. Banat, Ramzi Mujahed, Sama S. Yaseen, Nada A. Makhalfeh, Shahed O. Rajabi, Baraa Abu Aisheh, Rama N. BasheerPalestine Polytechnic University. Princess Alia Governmental Hospital.Palestine MedicineMedicine 2025; 104: DOI: 10.1097/MD.0000000000044225 AbstractRationale: Trisomy 18, often known as Edwards syndrome. It is a common chromosomal disorder characterized by the presence of an extra chromosome 18. Unfortunately, survival past

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Early postnatal right-to-left patent ductus arteriosus shunting and severe outcomes in neonates with congenital diaphragmatic hernia: a retrospective cohort study

Jung Il Kwak, Juhee Park, Mi Jin Kim, Kyusang Yoo, Bo Kyeong Jin, Tae-Gyeong Kim, Joo Hyung Roh, Ha Na Lee, Keon Hee Seol, Chae Young Kim, Soo Hyun Kim, Jiyoon Jeong, Byong Sop Lee, Euiseok JungAsan Medical Center Children’s Hospital and University of Ulsan College of Medicine. BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-05986-x

Early postnatal right-to-left patent ductus arteriosus shunting and severe outcomes in neonates with congenital diaphragmatic hernia: a retrospective cohort study Read More »

Large Patent Ductus Arteriosus in an Adult With Severe Pulmonary Hypertension and Polycythemia: PDA With Severe Pulmonary Hypertension

Tyler L. Langenfeld, Maram Sati, Martin L. Bocks, Arpit K. AgarwalRainbow Babies and Children’s Hospital. United States Journal of the American College of CardiologyJACC Case Rep 2025; 30: DOI: 10.1016/j.jaccas.2025.104677 AbstractBackground: Patent ductus arteriosus (PDA) is one of the most common cardiac abnormalities in children, but in rare cases it can go undiagnosed into adulthood until symptoms

Large Patent Ductus Arteriosus in an Adult With Severe Pulmonary Hypertension and Polycythemia: PDA With Severe Pulmonary Hypertension Read More »

General and Emergency Presentations of Children with Congenital Heart Defect and Factors Affecting it as Seen in A Tertiary Health Institution in Enugu

I. O. Arodiwe, I. A. Nwafor, F. A. Ujunwa, B. O. Edulu, J. M. Chinawa, T. A. Oguonu, N. Ezemba, J. C. EzeUniversity of Nigeria, Enugu Campus.Nigeria West Africa Journal of MedicineWest Africa J Med 2025; 42: 202-207DOI: Not Available AbstractBackground and objectives: The pattern of emergency presentations in children with congenital heart disease (CHD) is

General and Emergency Presentations of Children with Congenital Heart Defect and Factors Affecting it as Seen in A Tertiary Health Institution in Enugu Read More »

Case Report: Non-reactive vasoreactivity testing in a patient with patent ductus arteriosus with pulmonary hypertension: is there still a way to turn things around?

Sisca Natalia Siagian, Elsa Hedia Panjaitan, Pandu Prasetyo NugrohoUniversitas Indonesia.Indonesia Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2025; 12: DOI: 10.3389/fcvm.2025.1569963 AbstractBackground: Recent guidelines recommend patent ductus arteriosus (PDA) closure in adults based on hemodynamic criteria, such as pulmonary vascular resistance (PVR) and flow ratio (Qp:Qs). However, additional parameters like acute vasoreactivity testing (AVT) and closure testing, though

Case Report: Non-reactive vasoreactivity testing in a patient with patent ductus arteriosus with pulmonary hypertension: is there still a way to turn things around? Read More »

Utility of inhaled nitric oxide for pulmonary hypertension in cyanotic congenital heart disease: a cohort study with propensity score matching

Xiaofeng Wang, Chenyu Li, Shilin Wang, Zhiyuan Zhu, Qinnan Chen, Ruihuan Shen, Xu WangNational Center for Cardiovascular Disease and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College. Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences amd Affiliated Cardiovascular Hospital of Kunming Medical University. Sir Run Run Shaw Hospital and Zhejiang University

Utility of inhaled nitric oxide for pulmonary hypertension in cyanotic congenital heart disease: a cohort study with propensity score matching Read More »

Factors Influencing Prolonged Hospital Stay in Surgically Treated Children and Adolescents with Left-to-Right Shunt Congenital Heart Disease: Evidence From a Hospital in Southern China

Liudan Huang, Yuhua Zhang, Shaobo JiangMeizhou People’s Hospital and Meizhou Academy of Medical Sciences.China Therapeutics and Clinical Risk ManagementTher Clin Risk Manag 2025; DOI: 10.2147/TCRM.S533273 AbstractBackground: Congenital heart disease(CHD) is a congenital malformation caused by abnormal development of the heart and large blood vessels, and left-to-right shunt CHD is a relatively common type. Surgical treatment has the

Factors Influencing Prolonged Hospital Stay in Surgically Treated Children and Adolescents with Left-to-Right Shunt Congenital Heart Disease: Evidence From a Hospital in Southern China Read More »

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