Class 1. Persistent Pulmonary Hypertension of the Newborn

Association between immediate oxygenation response and survival in preterm infants receiving rescue inhaled nitric oxide therapy for hypoxemia from pulmonary hypertension: A systematic review and meta-analysis

Michelle Baczynski, Bonny Jasani, Charmaine De Castro, Carlo Dani, Nimish V. Subhedar, Praveen Chandrasekharan, Satvan Lakshminrusimha, Patrick J. McNamara, Adrianne R. Bishchoff, Amish JainMount Sinai Hospital. Hospital for Sick Children. Careggi University Hospital of Florence and University of Florence. Liverpool Women’s Hospital. University at Buffalo. UC Davis Children’s Hospital. University of Iowa. Canada, Italy, United

Association between immediate oxygenation response and survival in preterm infants receiving rescue inhaled nitric oxide therapy for hypoxemia from pulmonary hypertension: A systematic review and meta-analysis Read More »

Meconium aspiration syndrome: a comprehensive review

Ahmed Osman, Cecilie Halling, Mary Crume, Hayat Al Tabosh, Namrita Odackal, Molly K. BallThe Ohio State University and Nationwide Children’s Hospital. United States Journal of PerinatologyJ Perinatol 2023; DOI: 10.1038/s41372-023-01708-2 AbstractMeconium aspiration syndrome (MAS) is a complex respiratory disease that continues to be associated with significant morbidities and mortality. The pathophysiological mechanisms of MAS include airway

Meconium aspiration syndrome: a comprehensive review Read More »

Pulmonary hypertension associated with acute or chronic lung diseases in the preterm and term neonate and infant. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK

Anne Hilgendorff, Christian Apitz, Damien Bonnet, Georg HansmannDr von Haunersche Children’s Hospital. Children’s Hospital, University of Ulm. Hôpital Necker Enfants Malades, APHP, Université Paris Descartes. Hannover Medical School. Germany and France HeartHeart 2016; 102 Suppl 2: ii49-56DOI: 10.1136/heartjnl-2015-308591 AbstractPersistent pulmonary hypertension of the newborn (PPHN) is the most common neonatal form and mostly reversible after a few days

Pulmonary hypertension associated with acute or chronic lung diseases in the preterm and term neonate and infant. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK Read More »

Genome-wide association study identifies WWC2 as a possible locus associated with persistent pulmonary hypertension of the newborn in the Thai population

Narongsak Nakwan, Punna Kunhapan, Tassamonwan Chaiyasung, Nusara Satproedprai, Kamonnut Singkhamanan, Surakameth Mahasirimongkol, Chariyawan CharalsawadiPrince of Songkla University. Hat Yai Hospital. Ministry of Public Health. Thailand Translational PediatricsTransl Pediatr 2023; DOI: 10.21037/tp-22-280 AbstractBackground: There is known to be significant genetic involvement in persistent pulmonary hypertension of the newborn (PPHN), but to date there is not a clear understanding

Genome-wide association study identifies WWC2 as a possible locus associated with persistent pulmonary hypertension of the newborn in the Thai population Read More »

Omphalocele, Exstrophy of Cloaca, Imperforate Anus, and Spinal Defects Complex: A Case Report

Suraj Singh, Anuj Kayastha, Anupama Thapa, Bijay Thapa, Sulochana DahalKanti Children’s HospitalNepal Journal of the Nepal Medical AssociationJ Nepal Med Assoc 2022; 61: 375-378DOI: 10.31729/jnma.8048 AbstractOmphalocele, exstrophy of cloaca, imperforate anus, and spinal defects complex is a rare malformation complex that includes omphalocele, cloacal exstrophy, imperforate anus and spinal defects with the incidence of 1 in

Omphalocele, Exstrophy of Cloaca, Imperforate Anus, and Spinal Defects Complex: A Case Report Read More »

The use of milrinone in neonates with persistent pulmonary hypertension of the newborn – a randomised controlled trial pilot study (MINT 1)

Afif EL-Khuffash, Patrick J. McNamara, Colm Breatnach, Neidin Bussmann, Aisling Smith, Oliver Feeney, Elizabeth Tully, Joanna Griffin, Willem P. de Boode, Brian Cleary, Orla Franklin, Eugene DempseyThe Rotunda Hospital. Royal College of Surgeons in Ireland. University of Iowa. Radboud University Medical Center. Our Lady’s Children’s Hospital Crumlin. University College Cork.Ireland, United States and Netherlands Journal

The use of milrinone in neonates with persistent pulmonary hypertension of the newborn – a randomised controlled trial pilot study (MINT 1) Read More »

Case-based discussion: neonates on extracorporeal membrane oxygenation for undiagnosed recalcitrant pulmonary hypertension-management challenges

John A. King, Ajay Desai, Tom Semple, Andrew G. Nicholson, Andrew Bush, Samantha SonnappaRoyal Brompton Hospital. Imperial College London.United Kingdom ThoraxThorax 2023; 78: 107-109DOI: 10.1136/thorax-2021-217857 AbstractWe present two neonates requiring extracorporeal membrane oxygenation for undiagnosed recalcitrant pulmonary hypertension, highlighting the clinical and ethical dilemmas in management of very rare diseases. CategoryClass I. Persistent Pulmonary Hypertension of

Case-based discussion: neonates on extracorporeal membrane oxygenation for undiagnosed recalcitrant pulmonary hypertension-management challenges Read More »

Evaluation of newborns with Down syndrome with weight less than 1500 g in the neonatal intensive care unit: A Japanese multicentre study

Shuji Ishida, Hidehiko Nakanishi, Yukako Kosaka, Ayano Yamaguchi, Mari Ooka, the Neonatal Research NetworkKitasato University Hospital. Japan Journal pf Paediatrics and Child HealthJ Paediatr Child Health 2023; DOI: 10.1111/jpc.16418 AbstractAim: This study aimed to clarify the characteristics and their mortality-related factors in very low birthweight infants with Down syndrome (DS) in Japan.Methods: This retrospective case-control study enrolled newborns

Evaluation of newborns with Down syndrome with weight less than 1500 g in the neonatal intensive care unit: A Japanese multicentre study Read More »

Neonatal mortality and morbidity in Down syndrome in the time of prenatal aneuploidy testing: a retrospective cohort study

Maurike Dorothea de Groot‑van der Mooren, Brigitta Catharina Scheerman, Lukas Augustinus Johannes Rammeloo, Hester van Wieringen, Anne‑Marie van Wermeskerken, Roos van der Plas, Peter de Winter, Michel Emile Weijerman, Martina Cornelia Cornel, Anton Hubertus van KaamAmsterdam UMC Location University of Amsterdam. Amsterdam Public Health Research Institute. Amsterdam Reproduction & Development Research Institute. St. Antonius Ziekenhuis. Flevoziekenhuis, Hospitaalweg 1. Spaarne Gasthuis. KU Leuven. Alrijne Hospital. Netherlands and Belgium European Journal of PediatricsEur J Pediatr 2023; 182: 319-328DOI: 10.1007/s00431-022-04686-3 AbstractThe total uptake of prenatal

Neonatal mortality and morbidity in Down syndrome in the time of prenatal aneuploidy testing: a retrospective cohort study Read More »

Comparison of the efficacy of inhaled versus infused milrinone in the management of persistent pulmonary hypertension of the newborn in resource-limited settings: A randomized clinical trial

Farhad Abolhasan Choobdar, Peyman Shahhosseini, Zahra Vahedi, Nastaran Khosravi, Nasrin Khalesi, Maral GhassemzadehAli-Asghar Children’s Hospital, Firouzabadi Hospital and Iran University of Medical Sciences. Hakim Children’s Hospital and Tehran University of Medical Sciences.Iran Pediatric PulmonologyPediatr Pulmonol 2023; DOI: 10.1002/ppul.26451 AbstractBackground: The standard treatment for persistent pulmonary hypertension of the newborn (PPHN) is inhaled nitric oxide (iNO), which is

Comparison of the efficacy of inhaled versus infused milrinone in the management of persistent pulmonary hypertension of the newborn in resource-limited settings: A randomized clinical trial Read More »

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