Class 1. Persistent Pulmonary Hypertension of the Newborn

Case-based discussion: neonates on extracorporeal membrane oxygenation for undiagnosed recalcitrant pulmonary hypertension-management challenges

John A. King, Ajay Desai, Tom Semple, Andrew G. Nicholson, Andrew Bush, Samantha SonnappaRoyal Brompton Hospital. Imperial College London.United Kingdom ThoraxThorax 2023; 78: 107-109DOI: 10.1136/thorax-2021-217857 AbstractWe present two neonates requiring extracorporeal membrane oxygenation for undiagnosed recalcitrant pulmonary hypertension, highlighting the clinical and ethical dilemmas in management of very rare diseases. CategoryClass I. Persistent Pulmonary Hypertension of […]

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Evaluation of newborns with Down syndrome with weight less than 1500 g in the neonatal intensive care unit: A Japanese multicentre study

Shuji Ishida, Hidehiko Nakanishi, Yukako Kosaka, Ayano Yamaguchi, Mari Ooka, the Neonatal Research NetworkKitasato University Hospital. Japan Journal pf Paediatrics and Child HealthJ Paediatr Child Health 2023; DOI: 10.1111/jpc.16418 AbstractAim: This study aimed to clarify the characteristics and their mortality-related factors in very low birthweight infants with Down syndrome (DS) in Japan.Methods: This retrospective case-control study enrolled newborns

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Neonatal mortality and morbidity in Down syndrome in the time of prenatal aneuploidy testing: a retrospective cohort study

Maurike Dorothea de Groot‑van der Mooren, Brigitta Catharina Scheerman, Lukas Augustinus Johannes Rammeloo, Hester van Wieringen, Anne‑Marie van Wermeskerken, Roos van der Plas, Peter de Winter, Michel Emile Weijerman, Martina Cornelia Cornel, Anton Hubertus van KaamAmsterdam UMC Location University of Amsterdam. Amsterdam Public Health Research Institute. Amsterdam Reproduction & Development Research Institute. St. Antonius Ziekenhuis. Flevoziekenhuis, Hospitaalweg 1. Spaarne Gasthuis. KU Leuven. Alrijne Hospital. Netherlands and Belgium European Journal of PediatricsEur J Pediatr 2023; 182: 319-328DOI: 10.1007/s00431-022-04686-3 AbstractThe total uptake of prenatal

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Comparison of the efficacy of inhaled versus infused milrinone in the management of persistent pulmonary hypertension of the newborn in resource-limited settings: A randomized clinical trial

Farhad Abolhasan Choobdar, Peyman Shahhosseini, Zahra Vahedi, Nastaran Khosravi, Nasrin Khalesi, Maral GhassemzadehAli-Asghar Children’s Hospital, Firouzabadi Hospital and Iran University of Medical Sciences. Hakim Children’s Hospital and Tehran University of Medical Sciences.Iran Pediatric PulmonologyPediatr Pulmonol 2023; DOI: 10.1002/ppul.26451 AbstractBackground: The standard treatment for persistent pulmonary hypertension of the newborn (PPHN) is inhaled nitric oxide (iNO), which is

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Sildenafil Improves Pulmonary Vascular Remodeling in a Rat Model of Persistent Pulmonary Hypertension of the Newborn

Lili Kang, Xianghong Liu, Zilong Li, Xiao Mei Li, Yujie Han, Chen Liu, Cuifen Zhao, Xiaoying LiQilu Children’s Hospital of ShanDong University. Qilu Hospital and Cheeloo College of MedicineChina Journal of Cardiovascular PharmacologyJ Cardiovasc Pharmacol 2023; 81: 232-239DOI: 10.1097/FJC.0000000000001373 AbstractPersistent pulmonary hypertension of the newborn (PPHN) is characterized by pulmonary arterial remodeling mainly because of apoptosis

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Correlation of ABO blood groups with treatment response and efficacy in infants with persistent pulmonary hypertension of the newborn treated with inhaled nitric oxide

Yi Guan, Ya Jin, Yongxue Lu, Dang Ao, Pingjiao Gu, Jiyan Yang, Guosheng Liu, Shasha HanThe First Affiliated Hospital of Jinan University. The First People’s Hospital of Foshan. The Affiliated Hospital of Guangdong Medical University. Foshan Women and Children Hospital. Guangdong Women and Children Hospital. China BioMed Central Pregnancy and ChildbirthBMC Pregnancy Childbirth 2023; 23:

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Short-term Outcome and Predictors of Survival Among Neonates with Moderate or Severe Hypoxic Ischemic Encephalopathy: Data From the Indian Neonatal Collaborative

Chanchal Kumar, Guruprasad Peruri, Nishad Plakkal, Tejo Pretap Oleti, Abhishek Somasekhara Aradhya, Baswaraj Tandur, Deepak Chawla, Suman Rao, Mangalabharathi Sundaram, Nandkishor S. Kabra, Ashish A. Mehta, Sandeep Kadam Bijan Saha, Srinivas Murki, Praveen KumarJawaharlal Institute of Postgraduate Medical Education and Research. Fernandez Hospital. Ovum Woman and Child Speciality Hospital. Princess Durru Shehvar Children’s Hospital. Government

Short-term Outcome and Predictors of Survival Among Neonates with Moderate or Severe Hypoxic Ischemic Encephalopathy: Data From the Indian Neonatal Collaborative Read More »

Severe Congenital Syphilis in the Neonatal Intensive Care Unit: A Retrospective Case Series

Samia Aleem, LaShawndra Walker, Chi D. Hornik, Michael J. Smith, Chad A. Grotegut, Kristin E. D. WeimerDuke University. Wake Forest Baptist Health.United States Pediatric Infectious Disease JournalPediatr Infect Dis J 2022; 41: 335-339DOI: 10.1097/INF.0000000000003370 AbstractBackground: There has been a 291% relative increase in congenital syphilis (CS) cases in the United States from 2015 to 2019. Although the

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Identification of the Key Pathways and Genes in Hypoxia Pulmonary Arterial Hypertension Following Intrauterine Growth Retardation

Weifen Zhu, Ziming Zhang, Weiwei Gui, Zheng Shen, Yixin Chen, Xueyao Yin, Li Liang, Lin LiThe Affiliated Sir Run Run Shaw Hospital, Children’s Hospital and The First Affiliated Hospital of Zhejiang University.China Frontiers in Molecular BiosciencesFront Mol Biosci 2022; DOI: 10.3389/fmolb.2022.789736 AbstractHigh-throughput sequencing and weighted gene co-expression network analysis (WGCNA) were used to identify susceptibility modules

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Bleeding Complications in Neonates Receiving Extracorporeal Membrane Oxygenation and Controlled Hypothermia

Swosti Joshi, Vilmaris Quinones Cardona, Erica Poletto, Ogechukwu MenkitiDrexel University College of Medicine Philadelphia. Saint Christopher’s Hospital for Children.United States American Journal of PerinatologyAm J Perinatol 2022; DOI: 10.1055/a-1786-8688 AbstractObjective: Safety and efficacy data on controlled hypothermia (CH) for neonates with moderate to severe hypoxic ischemic encephalopathy has been extrapolated to a subgroup of these patients who

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