Class 1. Persistent Pulmonary Hypertension of the Newborn

Study on the comparison between Bosentan and Macitentan in the treatment of persistent pulmonary hypertension of the newborns, simultaneously on sildenafil: A randomized double-blinded non-inferiority parallel clinical trial

Mandana Kashaki, Arash Mohazzab, Mohammad Radgoudarzi, Arash Bordbar, Sama DabbaghIran University of Medical Sciences. Shahid Akbar Abadi Hospital. Iran Pediatrics and NeonatologyPediatr Neonatol 2024; DOI: 10.1016/j.pedneo.2023.12.007 AbstractBackground: Persistent Pulmonary Hypertension of the newborn (PPHN) is characterized by sustained elevated Pulmonary Artery Pressure (PAP). Drug resistance and the adverse effects of current therapeutic agents warrant investigation of other […]

Study on the comparison between Bosentan and Macitentan in the treatment of persistent pulmonary hypertension of the newborns, simultaneously on sildenafil: A randomized double-blinded non-inferiority parallel clinical trial Read More »

Transitional Hemodynamics in Neonates Born Through Meconium-Stained Amniotic Fluid: A Prospective Observational Study

Kamal Joshi, Mayank Priyadarshi, Yash Shrivastava, Suman Chaurasia, Poonam Signh, Nowneet Kumar Bhat, Sriparna BasuAll India Institute of Medical Sciences. India Pediatric CardiologyPediatr Cardiol 2024; DOI: 10.1007/s00246-024-03521-w AbstractNeonates born through meconium-stained amniotic fluid (MSAF) are at increased risk of altered cardiopulmonary transition at birth. There is a paucity of literature evaluating the transitional hemodynamics in these

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Enhancing Neonatal Care: The Vital Role of Pulse Oximetry in the Early Screening of Critical Congenital Heart Diseases and Respiratory Diseases in Rural Areas

Prajyoth M. Gaonkar, Saurabh R. Mutha, Isha M. SanghaniPunyashlok Ahilyadevi Holkar Government Medical College.India CureusCureus 2024; 16: DOI: 10.7759/cureus.58398 AbstractBackground: Pulse oximetry screening (POS) is acknowledged globally as a noninvasive method to detect critical congenital heart diseases (CCHDs) and respiratory illnesses. However, its value for early diagnosis and treatment remains unrecognized in many hospitals with limited

Enhancing Neonatal Care: The Vital Role of Pulse Oximetry in the Early Screening of Critical Congenital Heart Diseases and Respiratory Diseases in Rural Areas Read More »

Persistent Pulmonary Hypertension of the Newborn: Should Sildenafil and Inhaled Nitric Oxide at Medium Concentration Be the Standard of Treatment?

Ivan D. Florez, Luisa Parra-RodasUniversidad de Antioquia. McMaster University. Clínica Las Américas-AUNA. Universidad Pontificia Bolivariana.Columbia and Canada Critical Care MedicineCrit Care Med 2024; 52: 995-997DOI: 10.1097/CCM.0000000000006278 AbstractAbstract Not Available (Editorial) CategoryClass I. Persistent Pulmonary Hypertension of the NewbornMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Filed (PHiled).

Persistent Pulmonary Hypertension of the Newborn: Should Sildenafil and Inhaled Nitric Oxide at Medium Concentration Be the Standard of Treatment? Read More »

Milrinone in persistent pulmonary hypertension of newborn: a scoping review

Radu Galis, Diane Mudura, Paula Trif, Shivashankar Diggikar, Arun Prasath, Maria Livia Ognean, Jan Mazela, Adrian Lacatusu, Rangasamy Ramanathan, Boris W. Kramer, Yogen SinghEmergency County Hospital Bihor. Poznan University of Medical Sciences. University of Oradea. Oyster Woman and Child Hospital. University of Texas Southwestern. Lucian Blaga University Sibiu. Clinical County Emergency Hospital Sibiu. Emergency County

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A Nomogram Prediction Model for Persistent Pulmonary Hypertension of the Newborn in Neonates Hospitalized for the First Time After Birth

Yan Zhang, Juan Wen, Min Zeng, Limei Zhang, Yusheng PangFirst Affiliated Hospital of Guangxi Medical University. Women’s Hospital of Nanjing Medical University and Nanjing Women and Children’s Healthcare Hospital.China Pediatric Emergency CarePediatr Emerg Care 2024; DOI: 10.1097/PEC.0000000000003167 AbstractObjective: Persistent pulmonary hypertension of the newborn (PPHN) is one of the critical neonatal diseases associated with high morbidity and

A Nomogram Prediction Model for Persistent Pulmonary Hypertension of the Newborn in Neonates Hospitalized for the First Time After Birth Read More »

Effect of prone positioning ventilation on pulmonary function in neonates during venous-arterial extracorporeal membrane oxygenation

Kai-Peng Sun, Si-Jia Zhou, Xiu-Hua Chen, Yi-Rong Zheng, Qiang ChenFujian Children’s Hospital (Fujian Branch of Shanghai Children’s Medical Center) and Fujian Medical University.China Translational PediatricsTransl Pediatr 2024; 13: 575-583DOI: 10.21037/tp-23-485 AbstractBackground: The use of extracorporeal membrane oxygenation (ECMO) technology has significantly decreased mortality rates associated with neonatal pulmonary hypertension and respiratory failure. Prone positioning ventilation (PPV) is

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Persistent Pulmonary Hypertension of Newborns Secondary to Labile Hypoxemia Associated With Cyanosis: A Case Series

Anushka P. Bhagwat, H. V. Sharath, Nikita H. Seth, Saurabh N. PuriDatta Meghe Institute of Higher Education and Research.India CureusCureus 2024; 16:DOI: 10.7759/cureus.54016 AbstractPersistent pulmonary hypertension of the newborn (PPHN) is a condition that can be fatal, marked by increased pulmonary vascular resistance that causes blood to shunt from the right to the left. Six infants

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Occurrence of hyperoxia during iNO treatment for persistent pulmonary hypertension of the newborn: a cohort study

Justine de Jager, Fleur Brouwer, Jeroen Reijman, Roel L. F. van der Palen, Sylke J. Steggerda, Remco Visser, Arjan B. te Pas, Janneke DekkerLeiden University Medical Center.Netherlands European Journal of PediatricsEur J Pediatr 2024;DOI: 10.1007/s00431-024-05506-6 AbstractHigh concentrations of oxygen are often needed to optimize oxygenation in infants with persistent pulmonary hypertension (PPHN), but this can also

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Neonatal persistent pulmonary hypertension related to a novel TBX4 mutation: case report and review of the literature

Chiara Maddaloni, Sara Ronci, Domenico Umberto De Rose, Iliana Bersani, Francesca Campi, Matteo Di Nardo, Francesca Stoppa, Rachele Adorisio, Antonio Amodeo, Alessandra Toscano, Maria Cristina Digilio, Antonio Novelli, Giovanni Chello, Annabella Braguglia, Andrea Dotta, Flaminia Calzolar“Bambino Gesù” Children’s Hospital IRCCS. Monaldi Hospital.Italy Italian Journal of PediatricsItal J Pediatr 2024; 50:DOI: 10.1186/s13052-024-01575-3 AbstractTBX4 gene, located on human

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